Mechanism of anti-hyperglycemic action of Vatairea macrocarpa (Leguminosae): Investigation in peripheral tissues

Journal of Ethnopharmacology

Volumn 131, Issue 1, 2010, Pages 135-139

  Baviloni, Paula Domingues ^a   dos Santos, Maísa Pavani ^a   Aiko, Gustavo Mitsuo ^a   de Lima Reis, Silvia Regina ^a   Latorraca, Márcia Queiroz ^a   da Silva, Virginia Claudia ^a   Dall'Oglio, Evandro Luiz ^a   de Sousa Júnior, Paulo Teixeira ^a   Lopes, Carbene França ^a   Baviera, Amanda Martins ^a   Kawashita, Nair Honda ^a  

^a FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

Author keywords

Diabetes mellitus; Gluconeogenesis; Insulin signaling; Leguminosae; Protein kinases; Vatairea macrocarp

Indexed keywords

INSULIN; INSULIN RECEPTOR; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PLANT EXTRACT; PROTEIN KINASE B; UNCLASSIFIED DRUG; VATAIREA MACROCARPA EXTRACT;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARK; CONTROLLED STUDY; DIABETES CONTROL; DRUG MECHANISM; EXTENSOR DIGITORUM LONGUS MUSCLE; GLYCEMIC CONTROL; HYPERGLYCEMIA; LEGUME; LIVER; MALE; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STREPTOZOCIN DIABETES; VATAIREA MACROCARPA;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; FABACEAE; HYPOGLYCEMIC AGENTS; INSULIN; LIVER; MALE; MUSCLE, SKELETAL; PLANT BARK; PLANT EXTRACTS; PLANT STEMS; RATS; RATS, WISTAR;

ANIMALIA; FABACEAE; RATTUS; VATAIREA; VATAIREA MACROCARPA;

EID: 77955329181     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.06.015     Document Type: Article

References (21)

1. American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care 2007, 30:S42-S47.
2. Balasubramanyam M., Mohan V. Insulin signaling in diabetes: cascades and complexities. Advanced Biotechnology 2004, 2:24-27.
3. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976, 72:248-254.
4. Bryant N.J., Govers R., James D.E. Regulated transport of the glucose transporter GLUT4. Nature Reviews: Molecular Cell Biology 2002, 3:267-277.
5. Carvalho A.R. Popular use, chemical composition and trade of Cerrado's medicinal plants (Goias, Brazil). Environment, Development and Sustainability 2004, 6:307-316.
6. Chi T.C., Chen W.P., Chi T.L., Kuo T.F., Lee S.S., Cheng J.T., Su M.J. Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats. Life Sciences 2007, 80:1713-1720.
7. 13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes. The Journal of Clinical Investigation 1994, 94:2369-2376.
8. Guarim Neto G., Morais R.G. Medicinal plant resources in the Cerrado of Mato Grosso. Acta Botanica Brasilica 2003, 17:561-584.
9. Jesus N.Z., Lima J.C., Silva R.M., Espinosa M.M., Martins D.T. Ethnobotanical survey of plants popularly used as anti-ulcer and anti-inflammatory in Pirizal, Nossa Senhora do Livramento/Mato Grosso, Brazil. Brazilian Journal of Pharmacognosy 2009, 19:130-139.
10. Kahn B.B. Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance. Cell 1998, 92:593-596.
11. Kawahito S., Kitahata H., Oshita S. Problems associated with glucose toxicity: role of hyperglycemia-induced oxidative stress. World Journal of Gastroenterology 2009, 15:4137-4142.
12. Kikkawa R. Chronic complications in diabetes mellitus. British Journal of Nutrition 2000, 84:S183-S185.
13. Mohammad S., Taha A., Akhtar K., Bamezai R.N., Baquer N.Z. In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats. Canadian Journal of Physiology and Pharmacology 2006, 84:647-654.
14. Oliveira H.C., Santos M.P., Grigulo R., Lima L.L., Martins D.T., Lima J.C., Stoppiglia L.F., Lopes C.F., Kawashita N.H. Antidiabetic activity of Vatairea macrocarpa extract in rats. Journal of Ethnopharmacology 2008, 115:515-519.
15. Saltiel A.R. New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 2001, 104:517-529.
16. Schinner S., Scherbaum W.A., Bornstein S.R., Barthel A. Molecular mechanisms of insulin resistance. Diabetic Medicine 2005, 22:674-682.
17. Shalam M.D., Harish M.S., Farhana S.A. Prevention of dexamethasone- and fructose-induced insulin resistance in rats by SH-01D, a herbal preparation. Indian Journal of Pharmacology 2006, 38:419-422.
18. Shaw J.E., Sicree R.A., Zimmet P.Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research and Clinical Practice 2010, 87:4-14.
19. Velho G., Petersen K.F., Perseghin G., Hwang J.H., Rothman D.L., Pueyo M.E., Cline G.W., Froguel P., Shulman G.I. Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects. The Journal of Clinical Investigation 1996, 98:1755-1761.
20. White M.F., Khan C.R. The insulin signaling system. The Journal of Biological Chemistry 1994, 269:1-4.
21. Word Health Organization Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Report of WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus 1999, World Health Organization, Geneva.