PH-dependent interactions of human islet amyloid polypeptide segments with insulin studied by replica exchange molecular dynamics simulations

Journal of Physical Chemistry B

Volumn 114, Issue 31, 2010, Pages 10176-10183

  Jiang, Ping ^a   Wei, Lei ^a   Pervushin, Konstantin ^a   Mu, Yuguang ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOCHEMISTRY; COMPLEXATION; GLYCOPROTEINS; INSULIN; MOLECULAR DYNAMICS; PEPTIDES;

ACIDIC PH; AMYLOID DEPOSITION; AMYLOIDOGENESIS; COEXPRESSED; EXPERIMENTAL DATA; HELICAL MOTIFS; HUMAN ISLETS; IN-VIVO; INTERMOLECULAR CONTACTS; NEUTRAL PH; PEPTIDE INHIBITORS; PH VALUE; PH-DEPENDENT; POINT MUTATIONS; POLAR INTERACTIONS; POSITIVELY CHARGED; REPLICA-EXCHANGE MOLECULAR DYNAMICS SIMULATIONS; STACKING INTERACTION; TYPE II;

BINDING SITES;

EID: 77955321505     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp101811u     Document Type: Article

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