Suppression of PTP1B in gastric cancer cells in vitro induces a change in the genome-wide expression profile and inhibits gastric cancer cell growth

Cell Biology International

Volumn 34, Issue 7, 2010, Pages 747-753

  Wang, Jinguo ^a   Chen, Xuehua ^a   Liu, Bingya ^a   Zhu, Zhenggang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cell growth; Gastric cancer; Microarray analysis; Proliferation; PTP1B; Small interfering RNA

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE 1B; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL IMMORTALIZATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC TRANSFECTION; GROWTH INHIBITION; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH MUCOSA; WESTERN BLOTTING; ANIMAL; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; PATHOLOGY; REPRODUCIBILITY; STOMACH TUMOR; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; HUMANS; MICROARRAY ANALYSIS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; REPRODUCIBILITY OF RESULTS; RNA, SMALL INTERFERING; STOMACH NEOPLASMS;

EID: 77955316472     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20090447     Document Type: Article

References (33)

1. Alberts SR, Cervantes A, van de Velde CJ. Gastric cancer: epidemiology, pathology and treatment. Ann Oncol 2003;14:ii31-6.
2. Baehs S, Herbst A, Thieme SE, Perschl C, Behrens A, Scheel S et al. Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells. Cancer Lett 2009;276:152-9.
3. Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG et al. Neuronal PTP1B regulates body weight, adiposity and leptin action. Nat Med 2006;12:917-24.
4. Bentires-Alj M, Neel BG. Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer. Cancer Res 2007;67:2420-24.
5. Bjorge JD, Pang A, Fujita DJ. Identification of PTP1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines. J Biol Chem 2000;275:41439-46.
6. Brown-Shimer S, Johnson KA, Hill DE, Bruskin AM. Effect of protein tyrosine phosphatase 1B expression on transformation by the human neu oncogene. Cancer Res 1992;52:478-82.
7. Chernoff J, Schievella AR, Jost CA, Erikson RL, Neel BG. Cloning of a cDNA for a major human protein-tyrosine-phosphatase. Proc Natl Acad Sci USA 1990;87:2735-9.
8. Cimino D, Fuso L, Sfiligoi C, Biglia N, Ponzone R, Maggiorotto F et al. Identification of new genes associated with breast cancer progression by gene expression analysis of predefined sets of neoplastic tissues. Int J Cancer 2008;123:1327-38.
9. Conacci-Sorrell M, Kaplan A, Raveh S, Gavert N, Sakurai T, Ben-Ze'ev A. The shed ectodomain of Nr-CAM stimulates cell proliferation and motility, and confers cell transformation. Cancer Res 2005;65: 11605-12.
10. Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z et al. HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. J Biol Chem 2005;280:40066-73.
11. Ding L, Wang Z, Yan J, Yang X, Liu A, Qiu W et al. Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-blike signaling pathway. J Clin Invest 2009;119:349-61.
12. Dong W, Tu S, Xie J, Sun P, Wu Y, Wang L. Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer. Biochem Biophys Res Commun 2009;387:132-8.
13. Dubé N, Cheng A, Tremblay ML. The role of protein tyrosine phosphatase 1B in Ras signaling. Proc Natl Acad Sci USA 2004;101:1834-9.
14. Elchebly M, Payette P, Michaliszyn E, Cromlish W, Collins S, Loy AL et al. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science 1999;283:1544-8.
15. Gil-Puig C, Seoane S, Blanco M, Macia M, Garcia-Caballero T, Segura C et al. Pit-1 is expressed in normal and tumorous human breast and regulates GH secretion and cell proliferation. Eur J Endocrinol 2005;153:335-44.
16. Hou W, Medynski D, Wu S, Lin X, Li LY. VEGI-192, a new isoform of TNFSF15, specifically eliminates tumor vascular endothelial cells and suppresses tumor growth. Clin Cancer Res 2005;11:5955-602.
17. Julien SG, Dubé N, Read M, Penney J, Paquet M, Han Y et al. Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis. Nat Genet 2007;39:338-46.
18. LaMontagne KR, Jr, Hannon G, Tonks NK. Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of rat-1 fibroblasts and promotes differentiation of K562 cells. Proc Natl Acad Sci USA 1998;95:14094-9.
19. Leung WL, Wu MS, Kakugawa Y, Kim JJ, Yeoh KG, Goh KL et al. Screening for gastric cancer in Asia: current evidence and practice. Lancet Oncol 2008;9:279-87.
20. Madden SL, Galella EA, Riley D, Bertelsen AH, Beaudry GA. Induction of cell growth regulatory genes by p53. Cancer Res 1996;56:5384-90.
21. Miao J, Wang Z, Provencher H, Muir B, Dahiya S, Carney E et al. HOXB13 promotes ovarian cancer progression. Proc Natl Acad Sci USA 2007;104:17093-8.
22. Nanney LB, Davidson MK, Gates RE, Kano M, King LE, Jr. Altered distribution and expression of protein tyrosine phosphatases in normal human skin as compared to squamous cell carcinomas. J Cutan Pathol 1997;24:521-32.
23. Pillozzi S, Brizzi MF, Balzi M, Crociani O, Cherubini A, Guasti L et al. HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors. Leukemia 2002;16:1791-8.
24. Shen Y, Jia Z, Nagele RG, Ichikawa H, Goldberg GS. Src uses Cas to suppress Fhl1 in order to promote nonanchored growth and migration of tumor cells. Cancer Res 2006;66:1543-52.
25. Tubiana M. Tumor cell proliferation kinetics and tumor growth rate. Acta Oncol 1989;28:113-21.
26. Van Huijsduijnen RH, Bombrun A, Swinnen D. Selecting protein tyrosine phosphatases as drug targets. Drug Discov Today 2002;7:1013-9.
27. Wang Y, Qu Y, Li J, Chen X, Liu B, Gu Q et al. In vitro and in vivo evidence of metallopanstimulin-1 in gastric cancer progression and tumorigenicity. Clin Cancer Res 2006;12:4965-73.
28. Warabi M, Nemoto T, Ohashi K, Kitagawa M, Hirokawa K. Expression of protein tyrosine phosphatases and its significance in esophageal cancer. Exp Mol Pathol 2000;68:187-95.
29. Wiener JR, Hurteau JA, Kerns BJ, Whitaker RS, Conaway MR, Berchuck A et al. Overexpression of the tyrosine phosphatase PTP1B is associated with human ovarian carcinomas. Am J Obstet Gynecol 1994;170:1177-83.
30. Wu K, Li A, Rao M, Liu M, Dailey V, Yang Y et al. DACH1 is a cell fate determination factor that inhibits Cyclin D1 and breast tumor growth. Mol Cell Biol 2006;26:7116-29.
31. Yang SH, Seo MY, Jeong HJ, Jeung HC, Shin J, Kim SC et al. Gene copy number change events at chromosome 20 and their association with recurrence in gastric cancer patients. Clin Cancer Res 2005;11:612-20.
32. Zhang ZY. Protein tyrosine phosphatases: prospects for therapeutics. Curr Opin Chem Biol 2001;5:416-23.
33. Zhu S, Bjorge JD, Fujita DJ. PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation. Cancer Res 2007;67:10129-37.