메뉴 건너뛰기




Volumn 21, Issue 4, 2010, Pages 347-353

A 3-factor epistatic model predicts digital ulcers in Italian scleroderma patients

Author keywords

Cytokine; Digital ulcers; Epistasis; HLA; Petri nets; Systemic sclerosis

Indexed keywords

CYTOKINE; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2;

EID: 77955311023     PISSN: 09536205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejim.2010.05.010     Document Type: Article
Times cited : (8)

References (46)
  • 1
    • 0036124419 scopus 로고    scopus 로고
    • Systemic Sclerosis Study Group of the Italian Society of Rheumatology (SIR-GSSSc). Systemic sclerosis: Demographic, clinical, and serologic features and survival in 1,012 Italian patients
    • C. Ferri, G. Valentini, F. Cozzi, M. Sebastiani, C. Michelassi, and G. La Montagna Systemic Sclerosis Study Group of the Italian Society of Rheumatology (SIR-GSSSc). Systemic sclerosis: demographic, clinical, and serologic features and survival in 1,012 Italian patients Medicine (Baltimore) 81 2002 139 153
    • (2002) Medicine (Baltimore) , vol.81 , pp. 139-153
    • Ferri, C.1    Valentini, G.2    Cozzi, F.3    Sebastiani, M.4    Michelassi, C.5    La Montagna, G.6
  • 2
    • 67650470968 scopus 로고    scopus 로고
    • Clinical features of scleroderma patients with or without prior or current ischemic digital ulcers: Post-hoc analysis of a nationwide multicenter cohort (ItinerAIR-Sclerodermie)
    • K.P. Tiev, E. Diot, P. Clerson, F. Dupuis-Siméon, E. Hachulla, and P.Y. Hatron Clinical features of scleroderma patients with or without prior or current ischemic digital ulcers: post-hoc analysis of a nationwide multicenter cohort (ItinerAIR-Sclerodermie) J Rheumatol 36 2009 1470 1476
    • (2009) J Rheumatol , vol.36 , pp. 1470-1476
    • Tiev, K.P.1    Diot, E.2    Clerson, P.3    Dupuis-Siméon, F.4    Hachulla, E.5    Hatron, P.Y.6
  • 3
    • 34248379222 scopus 로고    scopus 로고
    • Clinical risk assessment of organ manifestations in systemic sclerosis: A report from the EULAR Scleroderma Trials and Research group database
    • U.A. Walker, A. Tyndall, L. Czirják, C. Denton, D. Farge-Bancel, and O. Kowal-Bielecka Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database Ann Rheum Dis 66 2007 754 763
    • (2007) Ann Rheum Dis , vol.66 , pp. 754-763
    • Walker, U.A.1    Tyndall, A.2    Czirják, L.3    Denton, C.4    Farge-Bancel, D.5    Kowal-Bielecka, O.6
  • 4
    • 36849082610 scopus 로고    scopus 로고
    • Natural history of ischemic digital ulcers in systemic sclerosis: Single-center retrospective longitudinal study
    • E. Hachulla, P. Clerson, D. Launay, M. Lambert, S. Morell-Dubois, and V. Queyrel Natural history of ischemic digital ulcers in systemic sclerosis: single-center retrospective longitudinal study J Rheumatol 34 2007 2423 2430
    • (2007) J Rheumatol , vol.34 , pp. 2423-2430
    • Hachulla, E.1    Clerson, P.2    Launay, D.3    Lambert, M.4    Morell-Dubois, S.5    Queyrel, V.6
  • 5
    • 62649152815 scopus 로고    scopus 로고
    • Comparison of patients with and without digital ulcers in systemic sclerosis: Detection of possible risk factors
    • C. Sunderkötter, I. Herrgott, C. Brückner, P. Moinzadeh, C. Pfeiffer, and J. Gerss Comparison of patients with and without digital ulcers in systemic sclerosis: detection of possible risk factors Br J Dermatol 160 2009 835 843
    • (2009) Br J Dermatol , vol.160 , pp. 835-843
    • Sunderkötter, C.1    Herrgott, I.2    Brückner, C.3    Moinzadeh, P.4    Pfeiffer, C.5    Gerss, J.6
  • 6
    • 67349203559 scopus 로고    scopus 로고
    • A score of risk factors associated with ischemic digital ulcers in patients affected by systemic sclerosis treated with iloprost
    • P. Caramaschi, N. Martinelli, A. Volpe, S. Pieropan, I. Tinazzi, and G. Patuzzo A score of risk factors associated with ischemic digital ulcers in patients affected by systemic sclerosis treated with iloprost Clin Rheumatol 28 2009 807 813
    • (2009) Clin Rheumatol , vol.28 , pp. 807-813
    • Caramaschi, P.1    Martinelli, N.2    Volpe, A.3    Pieropan, S.4    Tinazzi, I.5    Patuzzo, G.6
  • 8
    • 31144471309 scopus 로고    scopus 로고
    • Digital ulcers in patients with systemic sclerosis
    • L. Chung, and D. Fiorentino Digital ulcers in patients with systemic sclerosis Autoimmun Rev 5 2008 125 128
    • (2008) Autoimmun Rev , vol.5 , pp. 125-128
    • Chung, L.1    Fiorentino, D.2
  • 9
    • 14144253975 scopus 로고    scopus 로고
    • Increased plasma soluble CD40 ligand concentrations in systemic sclerosis and association with pulmonary arterial hypertension and digital ulcers
    • Y. Allanore, D. Borderie, C. Meune, H. Lemaréchal, S. Weber, and O.G. Ekindjian Increased plasma soluble CD40 ligand concentrations in systemic sclerosis and association with pulmonary arterial hypertension and digital ulcers Ann Rheum Dis 64 2005 481 483
    • (2005) Ann Rheum Dis , vol.64 , pp. 481-483
    • Allanore, Y.1    Borderie, D.2    Meune, C.3    Lemaréchal, H.4    Weber, S.5    Ekindjian, O.G.6
  • 11
    • 49149114916 scopus 로고    scopus 로고
    • Bosentan in systemic sclerosis
    • G.A. Heresi, and O.A. Minai Bosentan in systemic sclerosis Drugs Today (Barc) 44 2008 415 428
    • (2008) Drugs Today (Barc) , vol.44 , pp. 415-428
    • Heresi, G.A.1    Minai, O.A.2
  • 12
    • 0037444005 scopus 로고    scopus 로고
    • Interindividual variations in constitutive interleukin-10 messenger RNA and protein levels and their association with genetic polymorphisms
    • A. Suarez, P. Castro, R. Alonso, L. Mozo, and C. Gutierrez Interindividual variations in constitutive interleukin-10 messenger RNA and protein levels and their association with genetic polymorphisms Transplantation 75 2003 711 717
    • (2003) Transplantation , vol.75 , pp. 711-717
    • Suarez, A.1    Castro, P.2    Alonso, R.3    Mozo, L.4    Gutierrez, C.5
  • 13
    • 0026652591 scopus 로고
    • A TaqI polymorphism in the human interleukin-1β (IL-1β) gene correlates with IL-1β secretion in vitro
    • F. Pociot, J. Molvig, L. Wogensen, H. Worsaae, and J. Nerup A TaqI polymorphism in the human interleukin-1β (IL-1β) gene correlates with IL-1β secretion in vitro Eur J Clin Invest 22 1995 396 402
    • (1995) Eur J Clin Invest , vol.22 , pp. 396-402
    • Pociot, F.1    Molvig, J.2    Wogensen, L.3    Worsaae, H.4    Nerup, J.5
  • 14
    • 0032189103 scopus 로고    scopus 로고
    • The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
    • D. Fishman, G. Faulds, R. Jeffery, V. Mohamed-Ali, J.S. Yudkin, and S. Humphries The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis J Clin Invest 102 1998 1369 1376
    • (1998) J Clin Invest , vol.102 , pp. 1369-1376
    • Fishman, D.1    Faulds, G.2    Jeffery, R.3    Mohamed-Ali, V.4    Yudkin, J.S.5    Humphries, S.6
  • 15
    • 0035960384 scopus 로고    scopus 로고
    • Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes
    • S.C. Hoffmann, E.M. Stanley, E. Darrin Cox, N. Craighead, B.S. DiMercurio, and D.E. Koziol Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes Transplantation 72 2001 1444 1450
    • (2001) Transplantation , vol.72 , pp. 1444-1450
    • Hoffmann, S.C.1    Stanley, E.M.2    Darrin Cox, E.3    Craighead, N.4    Dimercurio, B.S.5    Koziol, D.E.6
  • 16
    • 33745022850 scopus 로고    scopus 로고
    • Cytokine gene polymorphism in human disease: On-line databases
    • M.V. Hollegaard, and J.L. Bidwell Cytokine gene polymorphism in human disease: on-line databases Genes Immun 7 2006 269 276
    • (2006) Genes Immun , vol.7 , pp. 269-276
    • Hollegaard, M.V.1    Bidwell, J.L.2
  • 18
    • 34250307119 scopus 로고    scopus 로고
    • Interleukin-1 gene complex polymorphisms in systemic sclerosis patients with severe restrictive lung physiology
    • L. Beretta, F. Bertolotti, F. Cappiello, M. Barili, M. Masciocchi, and K. Toussoun Interleukin-1 gene complex polymorphisms in systemic sclerosis patients with severe restrictive lung physiology Hum Immunol 68 2007 603 609
    • (2007) Hum Immunol , vol.68 , pp. 603-609
    • Beretta, L.1    Bertolotti, F.2    Cappiello, F.3    Barili, M.4    Masciocchi, M.5    Toussoun, K.6
  • 19
    • 33947604076 scopus 로고    scopus 로고
    • Proximal interleukin-10 gene polymorphisms in Italian patients with systemic sclerosis
    • L. Beretta, F. Cappiello, M. Barili, and R. Scorza Proximal interleukin-10 gene polymorphisms in Italian patients with systemic sclerosis Tissue Antigens 69 2007 305 312
    • (2007) Tissue Antigens , vol.69 , pp. 305-312
    • Beretta, L.1    Cappiello, F.2    Barili, M.3    Scorza, R.4
  • 20
    • 34548169544 scopus 로고    scopus 로고
    • No evidence for a role of the proximal IL-6 G/C-174 single nucleotide polymorphism in Italian patients with systemic sclerosis
    • L. Beretta, A. Santaniello, F. Cappiello, M. Barili, and R. Scorza No evidence for a role of the proximal IL-6 G/C-174 single nucleotide polymorphism in Italian patients with systemic sclerosis J Cell Mol Med 11 2007 896 898
    • (2007) J Cell Mol Med , vol.11 , pp. 896-898
    • Beretta, L.1    Santaniello, A.2    Cappiello, F.3    Barili, M.4    Scorza, R.5
  • 21
    • 47249132572 scopus 로고    scopus 로고
    • Ability of epistatic interactions of cytokine single-nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients
    • L. Beretta, F. Cappiello, J.H. Moore, M. Barili, C.S. Greene, and R. Scorza Ability of epistatic interactions of cytokine single-nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients Arthritis Rheum 59 2008 974 983
    • (2008) Arthritis Rheum , vol.59 , pp. 974-983
    • Beretta, L.1    Cappiello, F.2    Moore, J.H.3    Barili, M.4    Greene, C.S.5    Scorza, R.6
  • 22
    • 41549104833 scopus 로고    scopus 로고
    • Interleukin-1 gene complex single nucleotide polymorphisms in systemic sclerosis: A further step ahead
    • L. Beretta, F. Cappiello, J.H. Moore, and R. Scorza Interleukin-1 gene complex single nucleotide polymorphisms in systemic sclerosis: a further step ahead Hum Immunol 69 2008 187 192
    • (2008) Hum Immunol , vol.69 , pp. 187-192
    • Beretta, L.1    Cappiello, F.2    Moore, J.H.3    Scorza, R.4
  • 23
    • 33748414062 scopus 로고    scopus 로고
    • HLA-B35 upregulates the production of endothelin-1 in HLA-transfected cells: A possible pathogenetic role in pulmonary hypertension
    • A. Santaniello, G. Salazar, S. Lenna, R. Antonioli, G. Colombo, and L. Beretta HLA-B35 upregulates the production of endothelin-1 in HLA-transfected cells: a possible pathogenetic role in pulmonary hypertension Tissue Antigens 68 2006 239 244
    • (2006) Tissue Antigens , vol.68 , pp. 239-244
    • Santaniello, A.1    Salazar, G.2    Lenna, S.3    Antonioli, R.4    Colombo, G.5    Beretta, L.6
  • 24
    • 33847762833 scopus 로고    scopus 로고
    • HLA-B35 influences the apoptosis rate in human peripheral blood mononucleated cells and HLA-transfected cells
    • G. Salazar, G. Colombo, S. Lenna, R. Antonioli, L. Beretta, and A. Santaniello HLA-B35 influences the apoptosis rate in human peripheral blood mononucleated cells and HLA-transfected cells Hum Immunol 68 2007 181 191
    • (2007) Hum Immunol , vol.68 , pp. 181-191
    • Salazar, G.1    Colombo, G.2    Lenna, S.3    Antonioli, R.4    Beretta, L.5    Santaniello, A.6
  • 25
    • 0033850582 scopus 로고    scopus 로고
    • Anti-topoisomerase II alpha autoantibodies in systemic sclerosis-association with pulmonary hypertension and HLA-B35
    • B. Grigolo, I. Mazzetti, R. Meliconi, S. Bazzi, R. Scorza, and M. Candela Anti-topoisomerase II alpha autoantibodies in systemic sclerosis-association with pulmonary hypertension and HLA-B35 Clin Exp Immunol 121 2000 539 543
    • (2000) Clin Exp Immunol , vol.121 , pp. 539-543
    • Grigolo, B.1    Mazzetti, I.2    Meliconi, R.3    Bazzi, S.4    Scorza, R.5    Candela, M.6
  • 26
    • 0018887574 scopus 로고
    • Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutics Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma)
    • Anon
    • Anon Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutics Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma) Arthritis Rheum 23 1980 581 590
    • (1980) Arthritis Rheum , vol.23 , pp. 581-590
  • 27
    • 0034937852 scopus 로고    scopus 로고
    • Criteria for the classification of early systemic sclerosis
    • E.C. LeRoy, and T.A. Medsger Jr. Criteria for the classification of early systemic sclerosis J Rheumatol 28 2001 1573 1576
    • (2001) J Rheumatol , vol.28 , pp. 1573-1576
    • Leroy, E.C.1    Medsger Jr., T.A.2
  • 28
    • 0028920576 scopus 로고
    • Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease-modifying interventions. The American College of Rheumatlogy Committee on Design and Outcomes in Clinical Trials in Systemic Sclerosis
    • B. White, E.A. Bauer, L.A. Goldsmith, M.C. Hochberg, L.M. Katz, and J.H. Korn Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease-modifying interventions. The American College of Rheumatlogy Committee on Design and Outcomes in Clinical Trials in Systemic Sclerosis Sem Arthritis Rheum 38 1995 351 360
    • (1995) Sem Arthritis Rheum , vol.38 , pp. 351-360
    • White, B.1    Bauer, E.A.2    Goldsmith, L.A.3    Hochberg, M.C.4    Katz, L.M.5    Korn, J.H.6
  • 30
    • 34548184865 scopus 로고    scopus 로고
    • Polymorphism of immunoglobulin enhancer element HS1, 2A: Allele*2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency
    • D. Frezza, V. Giambra, B. Tolusso, M. De Santis, S. Bosello, and S. Vettori Polymorphism of immunoglobulin enhancer element HS1, 2A: allele*2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency Ann Rheum Dis 66 2007 1210 1215
    • (2007) Ann Rheum Dis , vol.66 , pp. 1210-1215
    • Frezza, D.1    Giambra, V.2    Tolusso, B.3    De Santis, M.4    Bosello, S.5    Vettori, S.6
  • 32
    • 0032040872 scopus 로고    scopus 로고
    • HLA class II region sequences
    • S.G.E. Marsh HLA class II region sequences Tissue Antigens 51 1998 467 507
    • (1998) Tissue Antigens , vol.51 , pp. 467-507
    • Marsh, S.G.E.1
  • 33
    • 0034973569 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction reveals high-order interactions among estrogen metabolism genes in sporadic breast cancer
    • M.D. Ritchie, L.W. Hahn, N. Roodi, L.R. Bailey, W.D. Dupont, and F.F. Parl Multifactor dimensionality reduction reveals high-order interactions among estrogen metabolism genes in sporadic breast cancer Am J Hum Genet 69 2001 138 147
    • (2001) Am J Hum Genet , vol.69 , pp. 138-147
    • Ritchie, M.D.1    Hahn, L.W.2    Roodi, N.3    Bailey, L.R.4    Dupont, W.D.5    Parl, F.F.6
  • 34
    • 0037433052 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction software for detecting gene-gene and gene-enviroment interactions
    • L.W. Hahn, M.D. Ritchie, and J.H. Moore Multifactor dimensionality reduction software for detecting gene-gene and gene-enviroment interactions Bioinformatics 19 2003 376 382
    • (2003) Bioinformatics , vol.19 , pp. 376-382
    • Hahn, L.W.1    Ritchie, M.D.2    Moore, J.H.3
  • 35
    • 34548802636 scopus 로고    scopus 로고
    • Tuning ReliefF for genome-wide genetic analysis
    • J.H. Moore, and B.C. White Tuning ReliefF for genome-wide genetic analysis Lect Notes Comput Sci 4447 2007 166 175
    • (2007) Lect Notes Comput Sci , vol.4447 , pp. 166-175
    • Moore, J.H.1    White, B.C.2
  • 36
    • 12844277447 scopus 로고    scopus 로고
    • Connecting the dots between genes, biochemistry, and disease susceptibility: Systems biology modeling in human genetics
    • J.H. Moore, E.M. Boczkob, and M.L. Summar Connecting the dots between genes, biochemistry, and disease susceptibility: systems biology modeling in human genetics Mol Genet Metab 84 2005 104 111
    • (2005) Mol Genet Metab , vol.84 , pp. 104-111
    • Moore, J.H.1    Boczkob, E.M.2    Summar, M.L.3
  • 37
    • 24644493356 scopus 로고    scopus 로고
    • Learning Petri net models of non-linear gene interactions
    • M. Mayo Learning Petri net models of non-linear gene interactions ByoSystems 82 2005 74 82
    • (2005) ByoSystems , vol.82 , pp. 74-82
    • Mayo, M.1
  • 38
    • 77955337037 scopus 로고    scopus 로고
    • Evolving concurrent Petri net models of epistasis
    • M. Mayo, and L. Beretta Evolving concurrent Petri net models of epistasis LNAI 5991 2010 166 175
    • (2010) LNAI , vol.5991 , pp. 166-175
    • Mayo, M.1    Beretta, L.2
  • 40
    • 37749022477 scopus 로고    scopus 로고
    • Clinical burden of digital vasculopathy in limited and diffuse cutaneous systemic sclerosis
    • S.I. Nihtyanova, G.M. Brough, C.M. Black, and C.P. Denton Clinical burden of digital vasculopathy in limited and diffuse cutaneous systemic sclerosis Ann Rheum Dis 67 2008 120 123
    • (2008) Ann Rheum Dis , vol.67 , pp. 120-123
    • Nihtyanova, S.I.1    Brough, G.M.2    Black, C.M.3    Denton, C.P.4
  • 41
    • 0026560191 scopus 로고
    • Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: Analysis of IL-6 production and IL-6R expression
    • A. Kitani, M. Hara, T. Hirose, K. Suzuki, M. Kawakami, and Y. Kawaguchi Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression Clin Exp Immunol 88 1992 75 83
    • (1992) Clin Exp Immunol , vol.88 , pp. 75-83
    • Kitani, A.1    Hara, M.2    Hirose, T.3    Suzuki, K.4    Kawakami, M.5    Kawaguchi, Y.6
  • 42
    • 55049118394 scopus 로고    scopus 로고
    • Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction
    • H. Ogura, M. Murakami, Y. Okuyama, M. Tsuruoka, C. Kitabayashi, and M. Kanamoto Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction Immunity 29 2008 628 636
    • (2008) Immunity , vol.29 , pp. 628-636
    • Ogura, H.1    Murakami, M.2    Okuyama, Y.3    Tsuruoka, M.4    Kitabayashi, C.5    Kanamoto, M.6
  • 45
    • 0025190231 scopus 로고
    • IL-2 dependence of the promotion of human B cell differentiation by IL-6 (BSF-2)
    • J.B. Splawski, L.M. McAnally, and P.E. Lipsky IL-2 dependence of the promotion of human B cell differentiation by IL-6 (BSF-2) J Immunol 144 1990 562 569
    • (1990) J Immunol , vol.144 , pp. 562-569
    • Splawski, J.B.1    McAnally, L.M.2    Lipsky, P.E.3
  • 46
    • 0034659754 scopus 로고    scopus 로고
    • Analysis of soluble and cell surface factors regulating anti-DNA topoisomerase i autoantibody production demonstrates synergy between Th1 and Th2 autoreactive T cells
    • M. Kuwana, T.A. Medsger Jr., and T.M. Wright Analysis of soluble and cell surface factors regulating anti-DNA topoisomerase I autoantibody production demonstrates synergy between Th1 and Th2 autoreactive T cells J Immunol 164 2000 6138 6146
    • (2000) J Immunol , vol.164 , pp. 6138-6146
    • Kuwana, M.1    Medsger Jr., T.A.2    Wright, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.