A WLM protein with SUMO-directed protease activity

Molecular and Cellular Biology

Volumn 30, Issue 15, 2010, Pages 3734-3736

  Su, Dan ^a   Hochstrasser, Mark ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; LYSINE; PROTEIN; PROTEINASE; SUMO PROTEIN; UNCLASSIFIED DRUG; WSS1 PROTEIN; SUMO 1 PROTEIN;

CARBOXY TERMINAL SEQUENCE; CHEMICAL ANALYSIS; ENZYME ACTIVITY; ENZYME REGULATION; IN VITRO STUDY; NONHUMAN; NOTE; PRIORITY JOURNAL; YEAST; ARTICLE; METABOLISM;

PROTEINS; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SUMO-1 PROTEIN;

EID: 77955298985     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00673-10     Document Type: Note

References (11)

1. Biggins, S., N. Bhalla, A. Chang, D. L. Smith, and A. W. Murray. 2001. Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159:453-470. (Pubitemid 33035092)
2. Denuc, A., and G. Marfany. 2010. SUMO and ubiquitin paths converge. Biochem. Soc. Trans. 38:34-39.
3. Geoffroy, M. C., and R. T. Hay. 2009. An additional role for SUMO in ubiquitin-mediated proteolysis. Nat. Rev. Mol. Cell Biol. 10:564-568.
4. Hannich, J. T., A. Lewis, M. B. Kroetz, S. J. Li, H. Heide, A. Emili, and M. Hochstrasser. 2005. Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J. Biol. Chem. 280:4102-4110.
5. Iyer, L. M., E. V. Koonin, and L. Aravind. 2004. Novel predicted peptidases with a potential role in the ubiquitin signaling pathway. Cell Cycle 3:1440-1450.
6. Li, S. J., and M. Hochstrasser. 2000. The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol. Cell. Biol. 20:2367-2377.
7. Mullen, J. R., and S. J. Brill. 2008. Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates. J. Biol. Chem. 283: 19912-19921.
8. Mullen, J. R., C.-F. Chen, and S. J. Brill. 2010. Wss1 is a SUMO-dependent isopeptidase that interacts genetically with the Slx5-Slx8 SUMO-targeted ubiquitin ligase. Mol. Cell. Biol. 30:3737-3748.
9. Perry, J. J., J. A. Tainer, and M. N. Boddy. 2008. A SIM-ultaneous role for SUMO and ubiquitin. Trends Biochem. Sci. 33:201-208.
10. Xie, Y., O. Kerscher, M. B. Kroetz, H. F. McConchie, P. Sung, and M. Hochstrasser. 2007. The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J. Biol. Chem. 282:34176-34184.
11. Yao, T., and R. E. Cohen. 2002. A cryptic protease couples deubiquitination and degradation by the proteasome. Nature 419:403-407.