Cox-2 gene expression in chemically induced skin papillomas cannot predict subsequent tumor fate

Molecular Oncology

Volumn 4, Issue 4, 2010, Pages 347-356

  Ishikawa, Tomo O ^a   Jain, Naveen K ^a   Herschman, Harvey R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cyclooxygenase; DMBA TPA; Gene expression; Knock in mouse; Luciferase; Skin cancer

Indexed keywords

CYCLOOXYGENASE 2; DIMETHYLBENZ[A]ANTHRACENE; FIREFLY LUCIFERASE;

ARTICLE; C57BL 6 MOUSE; CARCINOGENESIS; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SKIN PAPILLOMA;

MUS;

EID: 77955278978     PISSN: 15747891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molonc.2010.06.004     Document Type: Article

References (26)

1. An K.P., Athar M., Tang X., Katiyar S.K., Russo J., Beech J., Aszterbaum M., Kopelovich L., Epstein E.H., Mukhtar H., et al. Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: implications for therapeutic approaches. Photochem. Photobiol. 2002, 76(1):73-80.
2. Brecher A.R. The role of cyclooxygenase-2 in the pathogenesis of skin cancer. J. Drugs Dermatol. 2002, 1(1):44-47.
3. Collaco A.M., Geusz M.E. Monitoring immediate-early gene expression through firefly luciferase imaging of HRS/J hairless mice. BMC Physiol. 2003, 3:8.
4. Fischer S.M., Furstenberger G., Marks F., Slaga T.J. Events associated with mouse skin tumor promotion with respect to arachidonic acid metabolism: a comparison between SENCAR and NMRI mice. Cancer Res. 1987, 47(12):3174-3179.
5. Fischer S.M., Lo H.H., Gordon G.B., Seibert K., Kelloff G., Lubet R.A., Conti C.J. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol. Carcinog. 1999, 25(4):231-240.
6. Fischer S.M., Pavone A., Mikulec C., Langenbach R., Rundhaug J.E. Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis. Mol. Carcinog. 2007, 46(5):363-371.
7. Hennings H., Glick A.B., Lowry D.T., Krsmanovic L.S., Sly L.M., Yuspa S.H. FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin. Carcinogenesis 1993, 14(11):2353-2358.
8. Howe L.R., Dannenberg A.J. A role for cyclooxygenase-2 inhibitors in the prevention and treatment of cancer. Semin. Oncol. 2002, 29(3 Suppl. 11):111-119.
9. Ishikawa T., Jain N.K., Taketo M.M., Herschman H.R. Imaging cyclooxygenase-2 (Cox-2) gene expression in living animals with a luciferase knock-in reporter gene. Mol. Imaging Biol. 2006, 8(3):171-187.
10. Ishikawa T., Jain N., Herschman H.R. Feedback regulation of cyclooxygenase-2 transcription ex vivo and in vivo. Biochem. Biophys. Res. Commun. 2009, 378(3):534-538.
11. Ishikawa T., Kumar J.P., Machado H.B., Wong K., Kusewitt D., Huang S., Fischer S.M., Herschman H.R. Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis. Mol. Oncol. 2010, 4(2):119-125.
12. Johnson T.W., Anderson K.E., Lazovich D., Folsom A.R. Association of aspirin and nonsteroidal anti-inflammatory drug use with breast cancer. Cancer Epidemiol. Biomarkers Prev. 2002, 11(12):1586-1591.
13. Kemp C.J. Multistep skin cancer in mice as a model to study the evolution of cancer cells. Semin. Cancer Biol. 2005, 15(6):460-473.
14. Marks F., Furstenberger G., Muller-Decker K. Arachidonic acid metabolism as a reporter of skin irritancy and target of cancer chemoprevention. Toxicol. Lett. 1998, 96-97:111-118.
15. McCawley L.J., Wright J., LaFleur B.J., Crawford H.C., Matrisian L.M. Keratinocyte expression of MMP3 enhances differentiation and prevents tumor establishment. Am. J. Pathol. 2008, 173(5):1528-1539.
16. Muller-Decker K., Kopp-Schneider A., Marks F., Seibert K., Furstenberger G. Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2. Mol. Carcinog. 1998, 23(1):36-44.
17. Muller-Decker K., Reinerth G., Krieg P., Zimmermann R., Heise H., Bayerl C., Marks F., Furstenberger G. Prostaglandin-H-synthase isozyme expression in normal and neoplastic human skin. Int. J. Cancer 1999, 82(5):648-656.
18. Muller-Decker K., Scholz K., Marks F., Furstenberger G. Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis. Mol. Carcinog. 1995, 12(1):31-41.
19. Oshima M., Dinchuck J.E., Kargman S.L., Oshima H., Hancock B., Kwong E., Trzaskos J.M., Evans J.F., Taketo M.M. Suppression of intestinal polyposis in ApcD716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996, 87:803-809.
20. Quintanilla M., Brown K., Ramsden M., Balmain A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 1986, 322(6074):78-80.
21. Rauch D., Gross S., Harding J., Niewiesk S., Lairmore M., Piwnica-Worms D., Ratner L. Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors. Blood 2009, 113(7):1493-1500.
22. Scholz K., Furstenberger G., Muller-Decker K., Marks F. Differential expression of prostaglandin-H synthase isoenzymes in normal and activated keratinocytes in vivo and in vitro. Biochem. J. 1995, 309(Pt 1):263-269.
23. Smalley W.E., DuBois R.N. Colorectal cancer and nonsteroidal anti-inflammatory drugs. Adv. Pharmacol. 1997, 39:1-20.
24. Steinbach G., Lynch P.M., Phillips R.K., Wallace M.H., Hawk E., Gordon G.B., Wakabayashi N., Saunders B., Shen Y., Fujimura T., et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N. Engl. J. Med. 2000, 342(26):1946-1952.
25. Subbaramaiah K., Dannenberg A.J. Cyclooxygenase 2: a molecular target for cancer prevention and treatment. Trends Pharmacol. Sci. 2003, 24(2):96-102.
26. Tiano H.F., Loftin C.D., Akunda J., Lee C.A., Spalding J., Sessoms A., Dunson D.B., Rogan E.G., Morham S.G., Smart R.C., et al. Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis. Cancer Res. 2002, 62(12):3395-3401.