Biochemical and cellular effects of inhibiting Nedd8 conjugation

Biochemical and Biophysical Research Communications

Volumn 398, Issue 3, 2010, Pages 588-593

  Leck, Yee Chin ^a   Choo, Yin Yin ^a   Tan, Chia Yee ^a   Smith, Peter G ^b   Hagen, Thilo ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Actin cytoskeleton; Cullin RING E3 ligases; Nedd8; Neddylation; Protein degradation; RhoA; Ubc12; Ubiquitin

Indexed keywords

ACTIN; CULLIN; GUANOSINE TRIPHOSPHATASE; MLN 4924; NEDD8 PROTEIN; PROTEIN INHIBITOR; PROTEIN P27; PROTEIN UBC12; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; CELL STRAIN HEK293; CELL STRUCTURE; CONJUGATION; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATORY MECHANISM;

ACTINS; CELL LINE; CULLIN PROTEINS; CYCLOPENTANES; CYTOSKELETON; HELA CELLS; HUMANS; PYRIMIDINES; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINS;

EID: 77955273232     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.06.128     Document Type: Article

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