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Volumn 39, Issue 6, 2010, Pages 801-818

Neuroendocrine tumors: A critical appraisal of management strategies

Author keywords

neuroendocrine tumors; overall survival; progression free survival; somatostatin analogs; tumor proliferation

Indexed keywords

ALPHA INTERFERON; ANGIOPEPTIN; OCTREOTIDE; SOMATOSTATIN DERIVATIVE;

EID: 77955207094     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3181ea5839     Document Type: Article
Times cited : (27)

References (89)
  • 1
    • 70350442637 scopus 로고    scopus 로고
    • Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors: A report from the PROMID Study Group
    • Rinke A, Muller HH, Schade-Brittinger C, et al. Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors: a report from the PROMID Study Group. J Clin Oncol. 2009;27(28): 4656Y4663.
    • (2009) J Clin Oncol , vol.27 , Issue.28 , pp. 4656-4663
    • Rinke, A.1    Muller, H.H.2    Schade-Brittinger, C.3
  • 3
    • 18844422974 scopus 로고    scopus 로고
    • Current status of gastrointestinal carcinoids
    • Modlin IM, Kidd M, Latich I, et al. Current status of gastrointestinal carcinoids. Gastroenterology. 2005;128(6):1717Y1751.
    • (2005) Gastroenterology , vol.128 , Issue.6 , pp. 1717-1751
    • Modlin, I.M.1    Kidd, M.2    Latich, I.3
  • 4
    • 18844457312 scopus 로고    scopus 로고
    • Enteroendocrine tumors other than carcinoid: A review of clinically significant advances
    • Warner RR. Enteroendocrine tumors other than carcinoid: a review of clinically significant advances. Gastroenterology. 2005;128(6): 1668Y1684.
    • (2005) Gastroenterology , vol.128 , Issue.6 , pp. 1668-1684
    • Warner, R.R.1
  • 5
    • 33644656922 scopus 로고    scopus 로고
    • The role of cytoreductive hepatic surgery as an adjunct to the management of metastatic neuroendocrine carcinomas
    • Hodul P, Malafa M, Choi J, et al. The role of cytoreductive hepatic surgery as an adjunct to the management of metastatic neuroendocrine carcinomas. Cancer Control. 2006;13(1):61Y71.
    • (2006) Cancer Control , vol.13 , Issue.1 , pp. 61-71
    • Hodul, P.1    Malafa, M.2    Choi, J.3
  • 6
    • 33646265386 scopus 로고    scopus 로고
    • Treatment of advanced carcinoid tumors
    • Lal A, Chen H. Treatment of advanced carcinoid tumors. Curr Opin Oncol. 2006;18(1):9Y15.
    • (2006) Curr Opin Oncol , vol.18 , Issue.1 , pp. 9-15
    • Lal, A.1    Chen, H.2
  • 7
    • 24344434242 scopus 로고    scopus 로고
    • Palliative management strategies of advanced gastrointestinal carcinoid neoplasms
    • Sartori P, Mussi C, Angelini C, et al. Palliative management strategies of advanced gastrointestinal carcinoid neoplasms. Langenbecks Arch Surg. 2005;390(5):391Y396.
    • (2005) Langenbecks Arch Surg , vol.390 , Issue.5 , pp. 391-396
    • Sartori, P.1    Mussi, C.2    Angelini, C.3
  • 8
    • 0036688512 scopus 로고    scopus 로고
    • Effect of surgery on the outcome of midgut carcinoid disease with lymph node and liver metastases
    • Hellman P, Lundstrom T, Ohrvall U, et al. Effect of surgery on the outcome of midgut carcinoid disease with lymph node and liver metastases. World J Surg. 2002;26(8):991Y997.
    • (2002) World J Surg , vol.26 , Issue.8 , pp. 991-997
    • Hellman, P.1    Lundstrom, T.2    Ohrvall, U.3
  • 9
    • 33845595332 scopus 로고    scopus 로고
    • Operative resection of primary carcinoid neoplasms in patients with liver metastases yields significantly better survival
    • Givi B, Pommier SJ, Thompson AK, et al. Operative resection of primary carcinoid neoplasms in patients with liver metastases yields significantly better survival. Surgery. 2006;140(6):891Y897.
    • (2006) Surgery , vol.140 , Issue.6 , pp. 891-897
    • Givi, B.1    Pommier, S.J.2    Thompson, A.K.3
  • 11
    • 13944277784 scopus 로고    scopus 로고
    • Somatostatin analogsVfrom new molecules to new applications
    • Pawlikowski M, Melen-Mucha G. Somatostatin analogsVfrom new molecules to new applications. Curr Opin Pharmacol. 2004;4(6):608Y613.
    • (2004) Curr Opin Pharmacol , vol.4 , Issue.6 , pp. 608-613
    • Pawlikowski, M.1    Melen-Mucha, G.2
  • 12
    • 0026787125 scopus 로고
    • Octreotide treatment of acromegaly. A randomized, multicenter study
    • Ezzat S, Snyder PJ, Young WF, et al. Octreotide treatment of acromegaly. A randomized, multicenter study. Ann Intern Med. 1992;117(9):711Y718.
    • (1992) Ann Intern Med , vol.117 , Issue.9 , pp. 711-718
    • Ezzat, S.1    Snyder, P.J.2    Young, W.F.3
  • 13
    • 0022508840 scopus 로고
    • Endocrine profile of a long-acting somatostatin derivative SMS 201-995. Study in normal volunteers following subcutaneous administration
    • del Pozo E, Neufeld M, Schluter K, et al. Endocrine profile of a long-acting somatostatin derivative SMS 201-995. Study in normal volunteers following subcutaneous administration. Acta Endocrinol (Copenh). 1986;111(4):433Y439.
    • (1986) Acta Endocrinol (Copenh) , vol.111 , Issue.4 , pp. 433-439
    • Del Pozo, E.1    Neufeld, M.2    Schluter, K.3
  • 14
    • 0030210915 scopus 로고    scopus 로고
    • Sandostatin LAR (microencapsulated octreotide acetate) in acromegaly: Pharmacokinetic and pharmacodynamic relationships
    • Grass P, Marbach P, Bruns C, et al. Sandostatin LAR (microencapsulated octreotide acetate) in acromegaly: pharmacokinetic and pharmacodynamic relationships. Metabolism. 1996;45 (8 suppl 1):27Y30.
    • (1996) Metabolism , vol.45 , Issue.8 SUPPL. 1 , pp. 27-30
    • Grass, P.1    Marbach, P.2    Bruns, C.3
  • 15
    • 0025424426 scopus 로고
    • Pharmacokinetics of the long-acting somatostatin analogue octreotide (SMS 201-995) in acromegaly
    • Nicholls J, Wynick D, Domin J, et al. Pharmacokinetics of the long-acting somatostatin analogue octreotide (SMS 201-995) in acromegaly. Clin Endocrinol (Oxf). 1990;32(5):545Y550.
    • (1990) Clin Endocrinol (Oxf) , vol.32 , Issue.5 , pp. 545-550
    • Nicholls, J.1    Wynick, D.2    Domin, J.3
  • 16
    • 0033053184 scopus 로고    scopus 로고
    • Octreotide acetate long-acting formulation versus open-label subcutaneous octreotide acetate in malignant carcinoid syndrome
    • Rubin J, Ajani J, Schirmer W, et al. Octreotide acetate long-acting formulation versus open-label subcutaneous octreotide acetate in malignant carcinoid syndrome. J Clin Oncol. 1999;17(2):600Y606.
    • (1999) J Clin Oncol , vol.17 , Issue.2 , pp. 600-606
    • Rubin, J.1    Ajani, J.2    Schirmer, W.3
  • 17
    • 10744220389 scopus 로고    scopus 로고
    • Lanreotide 60 mg, a new long-acting formulation: Effectiveness in the chronic treatment of acromegaly
    • Attanasio R, Baldelli R, Pivonello R, et al. Lanreotide 60 mg, a new long-acting formulation: effectiveness in the chronic treatment of acromegaly. J Clin Endocrinol Metab. 2003;88(11):5258Y5265.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.11 , pp. 5258-5265
    • Attanasio, R.1    Baldelli, R.2    Pivonello, R.3
  • 18
    • 0028905403 scopus 로고
    • Intramuscular injections of slow-release lanreotide (BIM 23014) in acromegalic patients previously treated with continuous subcutaneous infusion of octreotide (SMS 201-995)
    • Caron P, Cogne M, Gusthiot-Joudet B, et al. Intramuscular injections of slow-release lanreotide (BIM 23014) in acromegalic patients previously treated with continuous subcutaneous infusion of octreotide (SMS 201-995). Eur J Endocrinol. 1995;132(3):320Y325.
    • (1995) Eur J Endocrinol , vol.132 , Issue.3 , pp. 320-325
    • Caron, P.1    Cogne, M.2    Gusthiot-Joudet, B.3
  • 19
    • 0028048378 scopus 로고
    • Pharmacokinetic and pharmacodynamic properties of a long-acting formulation of the new somatostatin analogue, lanreotide, in normal healthy volunteers
    • Kuhn JM, Legrand A, Ruiz JM, et al. Pharmacokinetic and pharmacodynamic properties of a long-acting formulation of the new somatostatin analogue, lanreotide, in normal healthy volunteers. Br J Clin Pharmacol. 1994;38(3):213Y219.
    • (1994) Br J Clin Pharmacol , vol.38 , Issue.3 , pp. 213-219
    • Kuhn, J.M.1    Legrand, A.2    Ruiz, J.M.3
  • 20
    • 2342485029 scopus 로고    scopus 로고
    • Octreotide long-acting repeatable and lanreotide Autogel are equally effective in controlling growth hormone secretion in acromegalic patients
    • van Thiel SW, Romijn JA, Biermasz NR, et al. Octreotide long-acting repeatable and lanreotide Autogel are equally effective in controlling growth hormone secretion in acromegalic patients. Eur J Endocrinol. 2004;150(4):489Y495.
    • (2004) Eur J Endocrinol , vol.150 , Issue.4 , pp. 489-495
    • Van Thiel, S.W.1    Romijn, J.A.2    Biermasz, N.R.3
  • 21
    • 69749110763 scopus 로고    scopus 로고
    • ENETS consensus guidelines for the standards of care in neuroendocrine tumors: Biotherapy
    • Oberg K, Ferone D, Kaltsas G, et al. ENETS consensus guidelines for the standards of care in neuroendocrine tumors: biotherapy. Neuroendocrinology. 2009;90(2):209Y213.
    • (2009) Neuroendocrinology , vol.90 , Issue.2 , pp. 209-213
    • Oberg, K.1    Ferone, D.2    Kaltsas, G.3
  • 22
    • 37349068642 scopus 로고    scopus 로고
    • Poorly-differentiated endocrine carcinomas of midgut and hindgut origin
    • Ahlman H, Nilsson O, McNicol AM, et al. Poorly-differentiated endocrine carcinomas of midgut and hindgut origin. Neuroendocrinology. 2008;87(1):40Y46.
    • (2008) Neuroendocrinology , vol.87 , Issue.1 , pp. 40-46
    • Ahlman, H.1    Nilsson, O.2    McNicol, A.M.3
  • 23
    • 33847625870 scopus 로고    scopus 로고
    • Consensus guidelines for the management of patients with digestive neuroendocrine tumors: Why such guidelines and how we went about It
    • Rindi G, de Herder WW, O'Toole D, et al. Consensus guidelines for the management of patients with digestive neuroendocrine tumors: why such guidelines and how we went about It. Neuroendocrinology. 2006;84(3):155Y157.
    • (2006) Neuroendocrinology , vol.84 , Issue.3 , pp. 155-157
    • Rindi, G.1    De Herder, W.W.2    O'Toole, D.3
  • 24
    • 27644563564 scopus 로고    scopus 로고
    • Effect of octreotide LAR dose and weight on octreotide blood levels in patients with neuroendocrine tumors
    • Woltering EA, Mamikunian PM, Zietz S, et al. Effect of octreotide LAR dose and weight on octreotide blood levels in patients with neuroendocrine tumors. Pancreas. 2005;31(4):392Y400.
    • (2005) Pancreas , vol.31 , Issue.4 , pp. 392-400
    • Woltering, E.A.1    Mamikunian, P.M.2    Zietz, S.3
  • 25
    • 49649124111 scopus 로고    scopus 로고
    • Clinical value of monitoring plasma octreotide levels during chronic octreotide long-acting repeatable therapy in carcinoid patients
    • Woltering EA, Salvo VA, O'Dorisio TM, et al. Clinical value of monitoring plasma octreotide levels during chronic octreotide long-acting repeatable therapy in carcinoid patients. Pancreas. 2008;37(1):94Y100.
    • (2008) Pancreas , vol.37 , Issue.1 , pp. 94-100
    • Woltering, E.A.1    Salvo, V.A.2    O'Dorisio, T.M.3
  • 26
    • 58149347686 scopus 로고    scopus 로고
    • Comments on BClinical value of monitoring plasma octreotide levels during chronic octreotide long-acting repeatable therapy in carcinoid patients
    • author reply 336Y337
    • Schran HF, Hager DF. Comments on BClinical value of monitoring plasma octreotide levels during chronic octreotide long-acting repeatable therapy in carcinoid patients[. Pancreas. 2008;37(3): 334Y335; author reply 336Y337.
    • (2008) Pancreas , vol.37 , Issue.3 , pp. 334-335
    • Schran, H.F.1    Hager, D.F.2
  • 27
    • 77957343448 scopus 로고    scopus 로고
    • A prospective trial on the effect of body mass index and sex on plasma octreotide levels in patients undergoing long-term octreotide LAR therapy
    • Joseph S, Li G, Lindholm E, et al. A prospective trial on the effect of body mass index and sex on plasma octreotide levels in patients undergoing long-term octreotide LAR therapy. Pancreas. 2010.
    • (2010) Pancreas
    • Joseph, S.1    Li, G.2    Lindholm, E.3
  • 28
    • 70350647326 scopus 로고    scopus 로고
    • Biochemical testing for neuroendocrine tumors
    • Vinik AI, Silva MP, Woltering G, et al. Biochemical testing for neuroendocrine tumors. Pancreas. 2009;38(8):876Y889.
    • (2009) Pancreas , vol.38 , Issue.8 , pp. 876-889
    • Vinik, A.I.1    Silva, M.P.2    Woltering, G.3
  • 29
    • 72949085528 scopus 로고    scopus 로고
    • Review article: Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours
    • Modlin IM, Pavel M, Kidd M, et al. Review article: somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours. Aliment Pharmacol Ther. 2010;31(2):169Y188.
    • (2010) Aliment Pharmacol Ther , vol.31 , Issue.2 , pp. 169-188
    • Modlin, I.M.1    Pavel, M.2    Kidd, M.3
  • 30
    • 19944430318 scopus 로고    scopus 로고
    • Rapid and sustained relief from the symptoms of carcinoid syndrome: Results from an open 6-month study of the 28-day prolonged-release formulation of lanreotide
    • Ruszniewski P, Ish-Shalom S, Wymenga M, et al. Rapid and sustained relief from the symptoms of carcinoid syndrome: results from an open 6-month study of the 28-day prolonged-release formulation of lanreotide. Neuroendocrinology. 2004;80(4):244Y251.
    • (2004) Neuroendocrinology , vol.80 , Issue.4 , pp. 244-251
    • Ruszniewski, P.1    Ish-Shalom, S.2    Wymenga, M.3
  • 31
    • 3442884868 scopus 로고    scopus 로고
    • Consensus report on the use of somatostatin analogs for the management of neuroendocrine tumors of the gastroenteropancreatic system
    • Oberg K, Kvols L, Caplin M, et al. Consensus report on the use of somatostatin analogs for the management of neuroendocrine tumors of the gastroenteropancreatic system. Ann Oncol. 2004;15(6):966Y973.
    • (2004) Ann Oncol , vol.15 , Issue.6 , pp. 966-973
    • Oberg, K.1    Kvols, L.2    Caplin, M.3
  • 33
    • 0037434851 scopus 로고    scopus 로고
    • Factors associated with progression of carcinoid heart disease
    • Moller JE, Connolly HM, Rubin J, et al. Factors associated with progression of carcinoid heart disease. N Engl J Med. 2003;348(11):1005Y1015.
    • (2003) N Engl J Med , vol.348 , Issue.11 , pp. 1005-1015
    • Moller, J.E.1    Connolly, H.M.2    Rubin, J.3
  • 34
    • 43749108350 scopus 로고    scopus 로고
    • The role of somatostatin analogues in the treatment of neuroendocrine tumours
    • Grozinsky-Glasberg S, Grossman AB, Korbonits M. The role of somatostatin analogues in the treatment of neuroendocrine tumours. Mol Cell Endocrinol. 2008;286(1Y2):238Y250.
    • (2008) Mol Cell Endocrinol , vol.286 , Issue.1 Y2 , pp. 238-250
    • Grozinsky-Glasberg, S.1    Grossman, A.B.2    Korbonits, M.3
  • 35
    • 53849134827 scopus 로고    scopus 로고
    • Somatostatin analogues in the control of neuroendocrine tumours: Efficacy and mechanisms
    • Grozinsky-Glasberg S, Shimon I, Korbonits M, et al. Somatostatin analogues in the control of neuroendocrine tumours: efficacy and mechanisms. Endocr Relat Cancer. 2008;15(3):701Y720.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.3 , pp. 701-720
    • Grozinsky-Glasberg, S.1    Shimon, I.2    Korbonits, M.3
  • 36
    • 0033756265 scopus 로고    scopus 로고
    • The antitumoral effect of the long-acting somatostatin analog lanreotide in neuroendocrine tumors
    • Ducreux M, Ruszniewski P, Chayvialle JA, et al. The antitumoral effect of the long-acting somatostatin analog lanreotide in neuroendocrine tumors. Am J Gastroenterol. 2000;95(11):3276Y3281.
    • (2000) Am J Gastroenterol , vol.95 , Issue.11 , pp. 3276-3281
    • Ducreux, M.1    Ruszniewski, P.2    Chayvialle, J.A.3
  • 37
    • 64549123947 scopus 로고    scopus 로고
    • The antiproliferative effect of somatostatin analogs: Clinical relevance in patients with neuroendocrine gastro-entero-pancreatic tumours
    • Verslype C, Carton S, Borbath I, et al. The antiproliferative effect of somatostatin analogs: clinical relevance in patients with neuroendocrine gastro-entero-pancreatic tumours. Acta Gastroenterol Belg. 2009; 72(1):54Y58.
    • (2009) Acta Gastroenterol Belg , vol.72 , Issue.1 , pp. 54-58
    • Verslype, C.1    Carton, S.2    Borbath, I.3
  • 38
    • 33750980417 scopus 로고    scopus 로고
    • Lanreotide Autogel every 6 weeks compared with lanreotide microparticles every 3 weeks in patients with well differentiated neuroendocrine tumors: A phase III Study
    • Bajetta E, Procopio G, Catena L, et al. Lanreotide Autogel every 6 weeks compared with lanreotide microparticles every 3 weeks in patients with well differentiated neuroendocrine tumors: a phase III Study. Cancer. 2006;107(10):2474Y2481.
    • (2006) Cancer , vol.107 , Issue.10 , pp. 2474-2481
    • Bajetta, E.1    Procopio, G.2    Catena, L.3
  • 39
    • 4344699187 scopus 로고    scopus 로고
    • High-dose treatment with a long-acting somatostatin analogue in patients with advanced midgut carcinoid tumours
    • Welin SV, Janson ET, Sundin A, et al. High-dose treatment with a long-acting somatostatin analogue in patients with advanced midgut carcinoid tumours. Eur J Endocrinol. 2004;151(1):107Y112.
    • (2004) Eur J Endocrinol , vol.151 , Issue.1 , pp. 107-112
    • Welin, S.V.1    Janson, E.T.2    Sundin, A.3
  • 40
    • 70350448492 scopus 로고    scopus 로고
    • Is it time to widen the use of somatostatin analogs in neuroendocrine tumors?
    • Oberg KE. Is it time to widen the use of somatostatin analogs in neuroendocrine tumors? J Clin Oncol. 2009;27(28):4635Y4636.
    • (2009) J Clin Oncol , vol.27 , Issue.28 , pp. 4635-4636
    • Oberg, K.E.1
  • 41
    • 75749136964 scopus 로고    scopus 로고
    • Antitumor effect of somatostatin analogs in neuroendocrine tumors
    • author reply e43Ye44
    • Chua YJ, Michael M, Zalcberg JR, et al. Antitumor effect of somatostatin analogs in neuroendocrine tumors. J Clin Oncol. 2010;28(3):e41Ye42; author reply e43Ye44.
    • (2010) J Clin Oncol , vol.28 , Issue.3
    • Chua, Y.J.1    Michael, M.2    Zalcberg, J.R.3
  • 42
    • 41349108697 scopus 로고    scopus 로고
    • Gastric endocrine tumors type I: Treatment with long-acting somatostatin analogs
    • Campana D, Nori F, Pezzilli R, et al. Gastric endocrine tumors type I: treatment with long-acting somatostatin analogs. Endocr Relat Cancer. 2008;15(1):337Y342.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.1 , pp. 337-342
    • Campana, D.1    Nori, F.2    Pezzilli, R.3
  • 43
    • 33751001270 scopus 로고    scopus 로고
    • Rationale for the use of somatostatin analogs as antitumor agents
    • Susini C, Buscail L. Rationale for the use of somatostatin analogs as antitumor agents. Ann Oncol. 2006;17(12):1733Y1742.
    • (2006) Ann Oncol , vol.17 , Issue.12 , pp. 1733-1742
    • Susini, C.1    Buscail, L.2
  • 44
    • 0023055355 scopus 로고
    • Somatostatin analogue (SMS 201-995) in the management of gastroenteropancreatic tumors and diarrhea syndromes
    • Vinik AI, Tsai ST, Moattari AR, et al. Somatostatin analogue (SMS 201-995) in the management of gastroenteropancreatic tumors and diarrhea syndromes. Am J Med. 1986;81(6B):23Y40.
    • (1986) Am J Med , vol.81 , Issue.6 B , pp. 23-40
    • Vinik, A.I.1    Tsai, S.T.2    Moattari, A.R.3
  • 45
    • 0025873494 scopus 로고
    • Growth of human breast cancer cell lines is inhibited by the somatostatin analog BIM23014
    • Prevost G, Foehrle E, Thomas F, et al. Growth of human breast cancer cell lines is inhibited by the somatostatin analog BIM23014. Endocrinology. 1991;129(1):323Y329.
    • (1991) Endocrinology , vol.129 , Issue.1 , pp. 323-329
    • Prevost, G.1    Foehrle, E.2    Thomas, F.3
  • 46
    • 0027818856 scopus 로고
    • Somatostatin analogs for diagnosis and treatment of cancer
    • Weckbecker G, Raulf F, Stolz B, et al. Somatostatin analogs for diagnosis and treatment of cancer. Pharmacol Ther. 1993; 60(2):245Y264.
    • (1993) Pharmacol Ther , vol.60 , Issue.2 , pp. 245-264
    • Weckbecker, G.1    Raulf, F.2    Stolz, B.3
  • 47
    • 0028670841 scopus 로고
    • Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas
    • Weckbecker G, Tolcsvai L, Stolz B, et al. Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas. Cancer Res. 1994;54(24):6334Y6337.
    • (1994) Cancer Res , vol.54 , Issue.24 , pp. 6334-6337
    • Weckbecker, G.1    Tolcsvai, L.2    Stolz, B.3
  • 48
    • 0026069006 scopus 로고
    • Somatostatin analogues inhibit angiogenesis in the chick chorioallantoic membrane
    • Woltering EA, Barrie R, O'Dorisio TM, et al. Somatostatin analogues inhibit angiogenesis in the chick chorioallantoic membrane. J Surg Res. 1991;50(3):245Y251.
    • (1991) J Surg Res , vol.50 , Issue.3 , pp. 245-251
    • Woltering, E.A.1    Barrie, R.2    O'Dorisio, T.M.3
  • 49
    • 0030996856 scopus 로고    scopus 로고
    • Somatostatin analogs: Angiogenesis inhibitors with novel mechanisms of action
    • Woltering EA, Watson JC, Alperin-Lea RC, et al. Somatostatin analogs: angiogenesis inhibitors with novel mechanisms of action. Invest New Drugs. 1997;15(1):77Y86.
    • (1997) Invest New Drugs , vol.15 , Issue.1 , pp. 77-86
    • Woltering, E.A.1    Watson, J.C.2    Alperin-Lea, R.C.3
  • 50
    • 0027369834 scopus 로고
    • Inhibition of angiogenesis by somatostatin and somatostatin-like compounds is structurally dependent
    • Barrie R,Woltering EA, Hajarizadeh H, et al. Inhibition of angiogenesis by somatostatin and somatostatin-like compounds is structurally dependent. J Surg Res. 1993;55(4):446Y450.
    • (1993) J Surg Res , vol.55 , Issue.4 , pp. 446-450
    • Barrie, R.1    Woltering, E.A.2    Hajarizadeh, H.3
  • 51
    • 0028051321 scopus 로고
    • Postreceptor signal transduction mechanisms involved in octreotide-induced inhibition of angiogenesis
    • Patel PC, Barrie R, Hill N, et al. Postreceptor signal transduction mechanisms involved in octreotide-induced inhibition of angiogenesis. Surgery. 1994;116(6):1148Y1152.
    • (1994) Surgery , vol.116 , Issue.6 , pp. 1148-1152
    • Patel, P.C.1    Barrie, R.2    Hill, N.3
  • 52
    • 0031019186 scopus 로고    scopus 로고
    • Inhibition of experimental angiogenesis by the somatostatin analogue octreotide acetate (SMS 201-995)
    • Danesi R, Agen C, Benelli U, et al. Inhibition of experimental angiogenesis by the somatostatin analogue octreotide acetate (SMS 201-995). Clin Cancer Res. 1997;3(2):265Y272.
    • (1997) Clin Cancer Res , vol.3 , Issue.2 , pp. 265-272
    • Danesi, R.1    Agen, C.2    Benelli, U.3
  • 53
    • 0029814429 scopus 로고    scopus 로고
    • The effects of the somatostatin analog octreotide on angiogenesis in vitro
    • Danesi R, Del Tacca M. The effects of the somatostatin analog octreotide on angiogenesis in vitro. Metabolism. 1996; 45(8 suppl 1):49Y50.
    • (1996) Metabolism , vol.45 , Issue.8 SUPPL. 1 , pp. 49-50
    • Danesi, R.1    Del Tacca, M.2
  • 54
    • 85047690366 scopus 로고    scopus 로고
    • Development of a novel in vitro human tissue-based angiogenesis assay to evaluate the effect of antiangiogenic drugs
    • discussion 798Y800
    • Woltering EA, Lewis JM, Maxwell PJT, et al. Development of a novel in vitro human tissue-based angiogenesis assay to evaluate the effect of antiangiogenic drugs. Ann Surg. 2003;237(6):790Y798; discussion 798Y800.
    • (2003) Ann Surg , vol.237 , Issue.6 , pp. 790-798
    • Woltering, E.A.1    Lewis, J.M.2    Pjt, M.3
  • 55
    • 0034934877 scopus 로고    scopus 로고
    • Growing vascular endothelial cells express somatostatin subtype 2 receptors
    • Watson JC, Balster DA, Gebhardt BM, et al. Growing vascular endothelial cells express somatostatin subtype 2 receptors. Br J Cancer. 2001;85(2):266Y272.
    • (2001) Br J Cancer , vol.85 , Issue.2 , pp. 266-272
    • Watson, J.C.1    Balster, D.A.2    Gebhardt, B.M.3
  • 56
    • 0041836171 scopus 로고    scopus 로고
    • Development of targeted somatostatin-based antiangiogenic therapy: A review and future perspectives
    • Woltering EA. Development of targeted somatostatin-based antiangiogenic therapy: a review and future perspectives. Cancer Biother Radiopharm. 2003;18(4):601Y609.
    • (2003) Cancer Biother Radiopharm , vol.18 , Issue.4 , pp. 601-609
    • Woltering, E.A.1
  • 57
    • 0029784011 scopus 로고    scopus 로고
    • Effect of a somatostatin analog (octreotide acetate) on the growth of retinal pigment epithelial cells in culture
    • Luo Q, Peyman GA, Conway MD, et al. Effect of a somatostatin analog (octreotide acetate) on the growth of retinal pigment epithelial cells in culture. Curr Eye Res. 1996;15(9):909Y913.
    • (1996) Curr Eye Res , vol.15 , Issue.9 , pp. 909-913
    • Luo, Q.1    Peyman, G.A.2    Conway, M.D.3
  • 58
    • 2442663041 scopus 로고    scopus 로고
    • Diabetes mellitus and retinopathy
    • Gargiulo P, Giusti C, Pietrobono D, et al. Diabetes mellitus and retinopathy. Dig Liver Dis. 2004;36(suppl 1):S101YS105.
    • (2004) Dig Liver Dis , vol.36 , Issue.SUPPL. 1
    • Gargiulo, P.1    Giusti, C.2    Pietrobono, D.3
  • 59
    • 0036315404 scopus 로고    scopus 로고
    • Somatostatin analogs inhibit neonatal retinal neovascularization
    • Higgins RD, Yan Y, Schrier BK. Somatostatin analogs inhibit neonatal retinal neovascularization. Exp Eye Res. 2002;74(5):553Y559.
    • (2002) Exp Eye Res , vol.74 , Issue.5 , pp. 553-559
    • Higgins, R.D.1    Yan, Y.2    Schrier, B.K.3
  • 60
    • 0027215419 scopus 로고
    • Somatostatin analogue phase i trials in neuroendocrine neoplasms
    • Anthony L, Johnson D, Hande K, et al. Somatostatin analogue phase I trials in neuroendocrine neoplasms. Acta Oncol. 1993;32(2):217Y223.
    • (1993) Acta Oncol , vol.32 , Issue.2 , pp. 217-223
    • Anthony, L.1    Johnson, D.2    Hande, K.3
  • 61
    • 0035985284 scopus 로고    scopus 로고
    • The clinical role of somatostatin analogues as antineoplastic agents: Much ado about nothing?
    • Hejna M, Schmidinger M, Raderer M. The clinical role of somatostatin analogues as antineoplastic agents: much ado about nothing? Ann Oncol. 2002;13(5):653Y668.
    • (2002) Ann Oncol , vol.13 , Issue.5 , pp. 653-668
    • Hejna, M.1    Schmidinger, M.2    Raderer, M.3
  • 62
    • 33747615699 scopus 로고    scopus 로고
    • Role of somatostatin analogs in the clinical management of non-neuroendocrine solid tumors
    • Kvols LK, Woltering EA. Role of somatostatin analogs in the clinical management of non-neuroendocrine solid tumors. Anticancer Drugs. 2006;17(6):601Y608.
    • (2006) Anticancer Drugs , vol.17 , Issue.6 , pp. 601-608
    • Kvols, L.K.1    Woltering, E.A.2
  • 63
    • 33845491265 scopus 로고    scopus 로고
    • Medical progress: Acromegaly
    • Melmed S. Medical progress: acromegaly. N Engl J Med. 2006;355(24):2558Y2573.
    • (2006) N Engl J Med , vol.355 , Issue.24 , pp. 2558-2573
    • Melmed, S.1
  • 64
    • 0024573688 scopus 로고
    • Use of somatostatin analog in management of carcinoid syndrome
    • Vinik A, Moattari AR. Use of somatostatin analog in management of carcinoid syndrome. Dig Dis Sci. 1989;34(suppl 3):14SY27S.
    • (1989) Dig Dis Sci , vol.34 , Issue.SUPPL. 3
    • Vinik, A.1    Moattari, A.R.2
  • 65
    • 0037233574 scopus 로고    scopus 로고
    • Expression of somatostatin receptor subtypes 1 to 5 in tumor tissue and intratumoral vessels in malignant endocrine pancreatic tumors
    • Fjallskog ML, Ludvigsen E, Stridsberg M, et al. Expression of somatostatin receptor subtypes 1 to 5 in tumor tissue and intratumoral vessels in malignant endocrine pancreatic tumors. Med Oncol. 2003;20(1):59Y67.
    • (2003) Med Oncol , vol.20 , Issue.1 , pp. 59-67
    • Fjallskog, M.L.1    Ludvigsen, E.2    Stridsberg, M.3
  • 66
    • 2342509665 scopus 로고    scopus 로고
    • The effect of drug dose and drug exposure time on the binding, internalization, and cytotoxicity of radiolabeled somatostatin analogs
    • Anthony CT, Hughey S, Lyons J, et al. The effect of drug dose and drug exposure time on the binding, internalization, and cytotoxicity of radiolabeled somatostatin analogs. J Surg Res. 2004;119(1):1Y13.
    • (2004) J Surg Res , vol.119 , Issue.1 , pp. 1-13
    • Anthony, C.T.1    Hughey, S.2    Lyons, J.3
  • 67
    • 77952756362 scopus 로고    scopus 로고
    • Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients
    • Reubi JC, Waser B, Cescato R, et al. Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients. J Clin Endocrinol Metab. 2010;95(5):2343Y2350.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.5 , pp. 2343-2350
    • Reubi, J.C.1    Waser, B.2    Cescato, R.3
  • 68
    • 0028203634 scopus 로고
    • Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: Mediation by human somatostatin receptor subtypes SSTR1 and SSTR2
    • Buscail L, Delesque N, Esteve JP, et al. Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc Natl Acad Sci U S A. 1994;91(6):2315Y2319.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.6 , pp. 2315-2319
    • Buscail, L.1    Delesque, N.2    Esteve, J.P.3
  • 69
    • 0031941299 scopus 로고    scopus 로고
    • Mechanisms of antineoplastic action of somatostatin analogs
    • Pollak MN, Schally AV. Mechanisms of antineoplastic action of somatostatin analogs. Proc Soc Exp Biol Med. 1998;217(2): 143Y152.
    • (1998) Proc Soc Exp Biol Med , vol.217 , Issue.2 , pp. 143-152
    • Pollak, M.N.1    Schally, A.V.2
  • 70
    • 0026041670 scopus 로고
    • The role of somatostatin and its analogs in the diagnosis and treatment of tumors
    • Lamberts SW, Krenning EP, Reubi JC. The role of somatostatin and its analogs in the diagnosis and treatment of tumors. Endocr Rev. 1991;12(4):450Y482.
    • (1991) Endocr Rev , vol.12 , Issue.4 , pp. 450-482
    • Lamberts, S.W.1    Krenning, E.P.2    Reubi, J.C.3
  • 71
    • 0035084694 scopus 로고    scopus 로고
    • Antiproliferative effect of somatostatin and analogs
    • Bousquet C, Puente E, Buscail L, et al. Antiproliferative effect of somatostatin and analogs. Chemotherapy. 2001;47(suppl 2):30Y39.
    • (2001) Chemotherapy , vol.47 , Issue.SUPPL. 2 , pp. 30-39
    • Bousquet, C.1    Puente, E.2    Buscail, L.3
  • 72
    • 0033756159 scopus 로고    scopus 로고
    • Lanreotide-induced modulation of 5-fluorouracil or mitomycin C cytotoxicity in human colon cancer cell lines: A preclinical study
    • Tesei A, Ricotti L, De Paola F, et al. Lanreotide-induced modulation of 5-fluorouracil or mitomycin C cytotoxicity in human colon cancer cell lines: a preclinical study. J Chemother. 2000;12(5):421Y430.
    • (2000) J Chemother , vol.12 , Issue.5 , pp. 421-430
    • Tesei, A.1    Ricotti, L.2    De Paola, F.3
  • 73
    • 0025799996 scopus 로고
    • The interrelationship between the anti-mitotic action of the somatostatin analog octreotide and that of cytostatic drugs and suramin
    • Lamberts SW, van Koetsveld P, Hofland LJ. The interrelationship between the anti-mitotic action of the somatostatin analog octreotide and that of cytostatic drugs and suramin. Int J Cancer. 1991;48(6): 938Y941.
    • (1991) Int J Cancer , vol.48 , Issue.6 , pp. 938-941
    • Lamberts, S.W.1    Van Koetsveld, P.2    Hofland, L.J.3
  • 74
    • 26244432792 scopus 로고    scopus 로고
    • SMS 201-995 enhances S-phase block induced by 5-fluorouracil in a human colorectal cancer cell line
    • Massari D, Trobonjac Z, Rukavina D, et al. SMS 201-995 enhances S-phase block induced by 5-fluorouracil in a human colorectal cancer cell line. Anticancer Drugs. 2005;16(9):989Y996.
    • (2005) Anticancer Drugs , vol.16 , Issue.9 , pp. 989-996
    • Massari, D.1    Trobonjac, Z.2    Rukavina, D.3
  • 75
    • 0027361903 scopus 로고
    • A somatostatin analogue (SMS 201-995) alters the toxicity of 5-fluorouracil in Swiss mice
    • Lee JM, Erlich RB, Bruckner HW, et al. A somatostatin analogue (SMS 201-995) alters the toxicity of 5-fluorouracil in Swiss mice. Anticancer Res. 1993;13(5A):1453Y1456.
    • (1993) Anticancer Res , vol.13 , Issue.5 A , pp. 1453-1456
    • Lee, J.M.1    Erlich, R.B.2    Bruckner, H.W.3
  • 76
    • 41349119602 scopus 로고    scopus 로고
    • Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors
    • Moreno A, Akcakanat A, Munsell MF, et al. Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors. Endocr Relat Cancer. 2008;15(1): 257Y266.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.1 , pp. 257-266
    • Moreno, A.1    Akcakanat, A.2    Munsell, M.F.3
  • 77
    • 73949088959 scopus 로고    scopus 로고
    • Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: A phase II trial
    • Yao JC, Lombard-Bohas C, Baudin E, et al. Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial. J Clin Oncol. 2010;28(1):69Y76.
    • (2010) J Clin Oncol , vol.28 , Issue.1 , pp. 69-76
    • Yao, J.C.1    Lombard-Bohas, C.2    Baudin, E.3
  • 78
    • 0025636501 scopus 로고
    • Antitumor effects of analogs of LH-RH and somatostatin: Experimental and clinical studies
    • Schally AV, Srkalovic G, Szende B, et al. Antitumor effects of analogs of LH-RH and somatostatin: experimental and clinical studies. J Steroid Biochem Mol Biol. 1990;37(6):1061Y1067.
    • (1990) J Steroid Biochem Mol Biol , vol.37 , Issue.6 , pp. 1061-1067
    • Schally, A.V.1    Srkalovic, G.2    Szende, B.3
  • 79
    • 77954793635 scopus 로고    scopus 로고
    • Updated safety and efficacy results of the phase III trial of sunitinib (SU) versus placebo (PBO) for treatment of pancreatic neuroendocrine tumors (NET)
    • Niccoli P, Raoul J, Bang Y, et al. Updated safety and efficacy results of the phase III trial of sunitinib (SU) versus placebo (PBO) for treatment of pancreatic neuroendocrine tumors (NET). J Clin Oncol. 2010;28(suppl):7s.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Niccoli, P.1    Raoul, J.2    Bang, Y.3
  • 80
    • 77954792867 scopus 로고    scopus 로고
    • Patient-reported outcomes (PROs) in patients (pts) with pancreatic neuroendocrine tumors (NET) receiving sunitinib (SU) in a phase III trial
    • Vinik A, Bang Y, Raoul J, et al. Patient-reported outcomes (PROs) in patients (pts) with pancreatic neuroendocrine tumors (NET) receiving sunitinib (SU) in a phase III trial. J Clin Oncol. 2010;28(suppl):7s.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Vinik, A.1    Bang, Y.2    Raoul, J.3
  • 81
    • 0033783951 scopus 로고    scopus 로고
    • Octreotide acetate long-acting release in patients with metastatic neuroendocrine tumors pretreated with lanreotide
    • Ricci S, Antonuzzo A, Galli L, et al. Octreotide acetate long-acting release in patients with metastatic neuroendocrine tumors pretreated with lanreotide. Ann Oncol. 2000;11(9):1127Y1130.
    • (2000) Ann Oncol , vol.11 , Issue.9 , pp. 1127-1130
    • Ricci, S.1    Antonuzzo, A.2    Galli, L.3
  • 82
    • 0037900591 scopus 로고    scopus 로고
    • Randomized clinical trial of the effect of interferon alpha on survival in patients with disseminated midgut carcinoid tumours
    • Kolby L, Persson G, Franzen S, et al. Randomized clinical trial of the effect of interferon alpha on survival in patients with disseminated midgut carcinoid tumours. Br J Surg. 2003;90(6):687Y693.
    • (2003) Br J Surg , vol.90 , Issue.6 , pp. 687-693
    • Kolby, L.1    Persson, G.2    Franzen, S.3
  • 83
    • 33750510023 scopus 로고    scopus 로고
    • A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas
    • Duran I, Kortmansky J, Singh D, et al. A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas. Br J Cancer. 2006;95(9):1148Y1154.
    • (2006) Br J Cancer , vol.95 , Issue.9 , pp. 1148-1154
    • Duran, I.1    Kortmansky, J.2    Singh, D.3
  • 84
    • 49149114782 scopus 로고    scopus 로고
    • Activity of sunitinib in patients with advanced neuroendocrine tumors
    • Kulke MH, Lenz HJ, Meropol NJ, et al. Activity of sunitinib in patients with advanced neuroendocrine tumors. J Clin Oncol. 2008;26(20):3403Y3410.
    • (2008) J Clin Oncol , vol.26 , Issue.20 , pp. 3403-3410
    • Kulke, M.H.1    Lenz, H.J.2    Meropol, N.J.3
  • 85
    • 21044451724 scopus 로고    scopus 로고
    • Radiolabeled somatostatin analog [177Lu-DOTA0,Tyr3]octreotate in patients with endocrine gastroenteropancreatic tumors
    • Kwekkeboom DJ, Teunissen JJ, Bakker WH, et al. Radiolabeled somatostatin analog [177Lu-DOTA0,Tyr3]octreotate in patients with endocrine gastroenteropancreatic tumors. J Clin Oncol. 2005;23(12):2754Y2762.
    • (2005) J Clin Oncol , vol.23 , Issue.12 , pp. 2754-2762
    • Kwekkeboom, D.J.1    Teunissen, J.J.2    Bakker, W.H.3
  • 86
    • 34547218122 scopus 로고    scopus 로고
    • Peptide receptor radionuclide therapy with 177Lu-octreotate in patients with foregut carcinoid tumours of bronchial, gastric and thymic origin
    • van Essen M, Krenning EP, Bakker WH, et al. Peptide receptor radionuclide therapy with 177Lu-octreotate in patients with foregut carcinoid tumours of bronchial, gastric and thymic origin. Eur J Nucl Med Mol Imaging. 2007;34(8):1219Y1227.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , Issue.8 , pp. 1219-1227
    • Van Essen, M.1    Krenning, E.P.2    Bakker, W.H.3
  • 87
    • 43749091955 scopus 로고    scopus 로고
    • Treatment with the radiolabeled somatostatin analog [177 Lu-DOTA 0,Tyr3]octreotate: Toxicity, efficacy, and survival
    • Kwekkeboom DJ, de Herder WW, Kam BL, et al. Treatment with the radiolabeled somatostatin analog [177 Lu-DOTA 0,Tyr3]octreotate: toxicity, efficacy, and survival. J Clin Oncol. 2008;26(13):2124Y2130.
    • (2008) J Clin Oncol , vol.26 , Issue.13 , pp. 2124-2130
    • Kwekkeboom, D.J.1    De Herder, W.W.2    Kam, B.L.3
  • 88
    • 0035871378 scopus 로고    scopus 로고
    • A phase II study of high-dose paclitaxel in patients with advanced neuroendocrine tumors
    • Ansell SM, Pitot HC, Burch PA, et al. A phase II study of high-dose paclitaxel in patients with advanced neuroendocrine tumors. Cancer. 2001;91(8):1543Y1548.
    • (2001) Cancer , vol.91 , Issue.8 , pp. 1543-1548
    • Ansell, S.M.1    Pitot, H.C.2    Burch, P.A.3
  • 89
    • 34249818466 scopus 로고    scopus 로고
    • Temozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors
    • Ekeblad S, Sundin A, Janson ET, et al. Temozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors. Clin Cancer Res. 2007;13(10):2986Y2991.
    • (2007) Clin Cancer Res , vol.13 , Issue.10 , pp. 2986-2991
    • Ekeblad, S.1    Sundin, A.2    Janson, E.T.3


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