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Volumn 15, Issue 1, 2008, Pages 257-266

Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; OCTREOTIDE; PROTEIN KINASE B; RAPAMYCIN; SOMATOSTATIN DERIVATIVE;

EID: 41349119602     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/ERC-07-0202     Document Type: Article
Times cited : (129)

References (30)
  • 3
    • 0035111692 scopus 로고    scopus 로고
    • Somatostatin inhibits Akt phosphorylation and cell cycle entry, but not p42/p44 mitogen-activated protein (MAP) kinase activation in normal and tumoral pancreatic acinar cells
    • Charland S, Boucher MJ, Houde M & Rivard N 2001 Somatostatin inhibits Akt phosphorylation and cell cycle entry, but not p42/p44 mitogen-activated protein (MAP) kinase activation in normal and tumoral pancreatic acinar cells. Endocrinology 142 121-128.
    • (2001) Endocrinology , vol.142 , pp. 121-128
    • Charland, S.1    Boucher, M.J.2    Houde, M.3    Rivard, N.4
  • 4
    • 33751162384 scopus 로고    scopus 로고
    • Therapeutic targets: MTOR and related pathways
    • Dancey JE 2006 Therapeutic targets: MTOR and related pathways. Cancer Biology and Therapy 5 1065-1073.
    • (2006) Cancer Biology and Therapy , vol.5 , pp. 1065-1073
    • Dancey, J.E.1
  • 5
    • 0035171928 scopus 로고    scopus 로고
    • The clinical management of neuroendocrine tumors with long-acting repeatable (LAR) octreotide: Comparison with standard subcutaneous octreotide therapy
    • Dogliotti L, Tampellini M, Stivanello M, Gorzegno G & Fabiani L 2001 The clinical management of neuroendocrine tumors with long-acting repeatable (LAR) octreotide: comparison with standard subcutaneous octreotide therapy. Annals of Oncology 12 S105-S109.
    • (2001) Annals of Oncology , vol.12
    • Dogliotti, L.1    Tampellini, M.2    Stivanello, M.3    Gorzegno, G.4    Fabiani, L.5
  • 11
    • 6044259204 scopus 로고    scopus 로고
    • Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells
    • Mondesire WH, Jian W, Zhang H, Ensor J, Hung MC, Mills GB & Meric-Bernstam F 2004 Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells. Clinical Cancer Research 10 7031-7042.
    • (2004) Clinical Cancer Research , vol.10 , pp. 7031-7042
    • Mondesire, W.H.1    Jian, W.2    Zhang, H.3    Ensor, J.4    Hung, M.C.5    Mills, G.B.6    Meric-Bernstam, F.7
  • 14
    • 0033809990 scopus 로고    scopus 로고
    • Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells
    • Perren A, Komminoth P, Saremaslani P, Matter C, Feurer S, Lees JA, Heitz PU & Eng C 2000 Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells. American Journal of Pathology 157 1097-1103.
    • (2000) American Journal of Pathology , vol.157 , pp. 1097-1103
    • Perren, A.1    Komminoth, P.2    Saremaslani, P.3    Matter, C.4    Feurer, S.5    Lees, J.A.6    Heitz, P.U.7    Eng, C.8
  • 15
    • 0033783951 scopus 로고    scopus 로고
    • Octreotide acetate long-acting release in patients with metastatic neuroendocrine tumors pretreated with lanreotide
    • Ricci S, Antonuzzo A, Galli L, Ferdeghini M, Bodei L, Orlandini C & Conte PF 2000 Octreotide acetate long-acting release in patients with metastatic neuroendocrine tumors pretreated with lanreotide. Annals of Oncology 11 1127-1130.
    • (2000) Annals of Oncology , vol.11 , pp. 1127-1130
    • Ricci, S.1    Antonuzzo, A.2    Galli, L.3    Ferdeghini, M.4    Bodei, L.5    Orlandini, C.6    Conte, P.F.7
  • 18
    • 27644534999 scopus 로고    scopus 로고
    • Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade
    • Shi Y, Yan H, Frost P, Gera J & Lichtenstein A 2005 Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade. Molecular Cancer Therapeutics 4 1533-1540.
    • (2005) Molecular Cancer Therapeutics , vol.4 , pp. 1533-1540
    • Shi, Y.1    Yan, H.2    Frost, P.3    Gera, J.4    Lichtenstein, A.5
  • 19
    • 23844438209 scopus 로고    scopus 로고
    • Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition
    • Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H & Khuri FR 2005 Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. Cancer Research 65 7052-7058.
    • (2005) Cancer Research , vol.65 , pp. 7052-7058
    • Sun, S.Y.1    Rosenberg, L.M.2    Wang, X.3    Zhou, Z.4    Yue, P.5    Fu, H.6    Khuri, F.R.7
  • 20
    • 33751001270 scopus 로고    scopus 로고
    • Rationale for the use of somatostatin analogs as antitumor agents
    • Susini C & Buscail L 2006 Rationale for the use of somatostatin analogs as antitumor agents. Annals of Oncology 17 1733-1742.
    • (2006) Annals of Oncology , vol.17 , pp. 1733-1742
    • Susini, C.1    Buscail, L.2
  • 21
    • 32944477371 scopus 로고    scopus 로고
    • Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression
    • Theodoropoulou M, Zhang J, Laupheimer S, Paez-Pereda M, Erneux C, Florio T, Pagotto U & Stalla GK 2006 Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression. Cancer Research 66 1576-1582.
    • (2006) Cancer Research , vol.66 , pp. 1576-1582
    • Theodoropoulou, M.1    Zhang, J.2    Laupheimer, S.3    Paez-Pereda, M.4    Erneux, C.5    Florio, T.6    Pagotto, U.7    Stalla, G.K.8
  • 23
    • 0036001209 scopus 로고    scopus 로고
    • Differential expression of the PTEN tumor suppressor protein in fetal and adult neuroendocrine tissues and tumors: Progressive loss of PTEN expression in poorly differentiated neuroendocrine neoplasms
    • Wang L, Ignat A & Axiotis CA 2002 Differential expression of the PTEN tumor suppressor protein in fetal and adult neuroendocrine tissues and tumors: progressive loss of PTEN expression in poorly differentiated neuroendocrine neoplasms. Applied Immunohistochemistry and Molecular Morphology 10 139-146.
    • (2002) Applied Immunohistochemistry and Molecular Morphology , vol.10 , pp. 139-146
    • Wang, L.1    Ignat, A.2    Axiotis, C.A.3
  • 24
    • 0031392104 scopus 로고    scopus 로고
    • Indirect antiproliferative effect of the somatostatin analog octreotide on MIA PaCa-2 human pancreatic carcinoma in nude mice
    • Weckbecker G, Raulf F, Bodmer D & Bruns C 1997 Indirect antiproliferative effect of the somatostatin analog octreotide on MIA PaCa-2 human pancreatic carcinoma in nude mice. Yale Journal of Biology and Medicine 70 549-554.
    • (1997) Yale Journal of Biology and Medicine , vol.70 , pp. 549-554
    • Weckbecker, G.1    Raulf, F.2    Bodmer, D.3    Bruns, C.4
  • 28
    • 33947271014 scopus 로고    scopus 로고
    • Neuroendocrine tumors. Molecular targeted therapy for carcinoid and islet-cell carcinoma
    • Yao JC 2007 Neuroendocrine tumors. Molecular targeted therapy for carcinoid and islet-cell carcinoma. Best Practice and Research, Clinical Endocrinology and Metabolism 21 163-172.
    • (2007) Best Practice and Research, Clinical Endocrinology and Metabolism , vol.21 , pp. 163-172
    • Yao, J.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.