Dendritic signals command firing dynamics in a mathematical model of cerebellar purkinje cells

Biophysical Journal

Volumn 99, Issue 2, 2010, Pages 427-436

  Genet, Stéphane ^a   Sabarly, Loïc ^a   Guigon, Emmanuel ^a   Berry, Hugues ^b   Delord, Bruno ^a  

^a UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

^b UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTION POTENTIAL; ANIMAL; BIOLOGICAL MODEL; CALCIUM SIGNALING; DENDRITE; METABOLISM; PHYSIOLOGY; PURKINJE CELL; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; ANIMALS; CALCIUM SIGNALING; DENDRITES; MODELS, NEUROLOGICAL; PURKINJE CELLS; SIGNAL TRANSDUCTION;

EID: 77955200834     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2010.04.056     Document Type: Article

References (37)

1. Ito, M. 1984. The Cerebellum and Neural Control. Raven. Press, New York.
2. Llinás, R., and M. Sugimori. 1980. Electrophysiological properties of in vitro Purkinje cell, somata in mammalian cerebellar slices. J. Physiol. 305:171-195. (Pubitemid 10048155)
3. Llinás, R., and M. Sugimori. 1980. Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices. J. Physiol. 305:197-213. (Pubitemid 10048156)
4. Llinás, R., and M. Sugimori. 1992. The electrophysiology of the cerebellar Purkinje cell revisited. In The Cerebellum Revisited. R. Llinás and C. Sotelo, editors. Springer Verlag, New York. 167-181.
5. Mintz, I. M., M. E. Adams, and B. P. Bean, 1992. P-type calcium channels in rat central and peripheral neurons. Neuron. 9:85-95.
6. Granit, R., and C. G. Phillips. 1956. Excitatory and inhibitory processes acting upon individual Purkinje cells of the cerebellum in cats. J. Physiol, 133:520-547.
7. Williams, S. R., S. R. Christen sen.....M. Hausser. 2002. Membrane potential, bistability is controlled by the hyperpolarization-activated current I(H) in rat cerebellar Purkinje neurons in vitro. J. Physiol. 539:469-483.
8. Loewenstein, Y., S. Manon, ...,M. Hausser. 2005. Bistability of cerebellar Purkinje cells modulated by sensory stimulation. Nat. Neurosci. 8:202-211. (Pubitemid 40194051)
9. Yartsev, M. M., R. Givon-Mayo, ..., O. Donchin. 2009. Pausing Purkinje cells in the cerebellum of the awake cat. Front. Syst. Neurosci. 3:2.
10. Rokni, D., and Y. Yarom. 2009. State-dependence of climbing fiberdriven calcium transients in Purkinje cells. Neuroscience. 162:694-701.
11. Genet, S., and B. Delord. 2002. A biophysical model, of nonlinear dynamics underlying plateau potentials and calcium spikes in Purkinje cell dendrites. J. Neurophysiol. 88:2430-2444. (Pubitemid 35346048)
12. Bekkers, J. M., and M. Hausser. 2007. Targeted dendrotomy reveals active and passive contributions of the dendritic tree to synaptic integration and neuronal output. Proc. Natl. Acad. Sci. USA. 104:11447-11452.
13. Monsivais, P., B. A. Clark.....M. Hausser. 2005. Determinants of action potential, propagation in. cerebellar Purkinje cell, axons. J. Neurosci. 25:464-472. (Pubitemid 40105617)
14. De Schutter, E., and J. M. Bower. 1994. An active membrane model of the cerebellar Purkinje cell. I. Simulation of current clamps in slice. J. Neurophysiol. 71:375-400. (Pubitemid 24058864)
15. Yuen, G. L., P. E. Hockberger, and J. C. Houk. 1995. Bistability in cerebellar Purkinje cell, dendrites modelled with high-threshold calcium and delayed-rectifier potassium channels. Biol. Cybern. 73:375-388.
16. Kreiner, L., and D. Jaeger. 2004. Synaptic shunting by a baseline of synaptic conductances modulates responses to inhibitory input volleys in cerebellar Purkinje cells. Cerebellum. 3:112-1.25. (Pubitemid 38797072)
17. McKay, B. E., and R, W. Turner. 2005. Physiological and morphological development of the rat cerebellar Purkinje cell. J. Physiol. 567:829-850.
18. Fernandez, F. R., J. D. Engbers, and R, W. Turner. 2007. Firing dynamics of cerebellar Purkinje cells. J. Neurophysiol. 98:278-294. (Pubitemid 47084819)
19. Shelton, D. P. 1985. Membrane reastivity estimated for the Purkinje neuron by means of a passive computer model. Neuroscience. 14:111-131.
20. Hille, B. 1992. Ionic Channels of Excitable Membranes. Sinauer, Sunderland, MA.
21. Vetter, P., A, Roth, and M. Hausser. 2001. Propagation of action potentials in dendrites depends on dendritic morphology. J. Neurophysiol. 85:926-937.
22. Britton, N. F. 1986. Reaction-Diffusion and Their Applications to Biology. Academic Press, London.
23. Llinás, R., C. Nicholson, ...,D. E. Hillman. 1968. Dendritic spikes and their inhibition in alligator Purkinje cells. Science. 160:1132-1135.
24. 2+]i increases in the dendrites of cerebellar Purkinje neurons. J. Neurosci. 15:2777-2787.
25. Miyakawa, H., V. Lev-Ram,..., W. N. Ross. 1992. Calcium transients evoked by climbing fiber and parallel fiber synaptic inputs in. guinea pig cerebellar Purkinje neurons. J. Neurophysiol. 68:1178-1189.
26. Ekerot, C. F., and O. Oscarsson. 1981. Prolonged depolarization elicited in Purkinje cell dendrites by climbing fibre impulses in the cat. J. Physiol. 318:207-221,
27. Chan, C. Y., J. Hounsgaard, and J. Midtgaard. 1989. Excitatory synaptic responses in turtle cerebellar Purkinje cells. J. Physiol. 409:143-156. (Pubitemid 19052976)
28. Rancz, E. A., and M. Hausser. 2006. Dendritic calcium spikes are tunable triggers of cannabinoid release and short-term synaptic plasticity in cerebellar Purkinje neurons. J. Neurosci. 26:5428-5437.
29. Campbell, N. C., C. F. Ekerot.....O. Oscarsson. 1983. Dendritic plateau potentials evoked in Purkinje cells by parallel fibre volleys in the cat. J. Physiol. 340:209-223.
30. Latham, A., and D. H. Paul. 1971, Spontaneous activity of cerebellar Purkinje cells and their responses to impulses in climbing fibres. J. Physiol. 213:135-156.
31. Roth, A., and M. Hausser. 2001. Compartmental models of rat cerebellar Purkinje cells based on simultaneous somatic and dendritic patch-clamp recordings. J. Physiol. 535:445-472. (Pubitemid 32825682)
32. + channels enable burst output in rat cerebellar Purkinje cells. Eur. J. Neurosci. 20:729-739.
33. Guan, S., S. Ma, ..., J. Wang. 2006. The postnatal development of refractory periods and threshold potentials at cerebellar Purkinje neurons. Brain Res. 1097:59-64. (Pubitemid 44041293)
34. Midtgaard, J. 1992. Stellate cell inhibition of Purkinje cells in the turtle cerebellum, in. vitro. J. Physiol. 457:355-367.
35. Jaeger, D., and J. M. Bower. 1999. Synaptic control of spiking in cerebellar Purkinje cells: dynamic current clamp based on model, conductances. J. Neurosci, 19:6090-6101. (Pubitemid 29327941)
36. Jaeger, D., E. De Schutter, and J. M. Bower. 1997. The role of synaptic and voltage-gated currents in the control, of Purkinje cell spiking: a modeling study. J. Neurosci. .17:91-106. (Pubitemid 27008853)
37. Shin, S. L., F. E. Hoebeek.....E. De Schutter. 2007. Regular patterns in cerebellar Purkinje cell simple spike trains. PLoS One. 2:e485.