The role of synaptic and voltage-gated currents in the control of Purkinje cell spiking: A modeling study

Journal of Neuroscience

Volumn 17, Issue 1, 1997, Pages 91-106

  Jaeger, Dieter ^a,c   De Schutter, Erik ^b   Bower, James M ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c EMORY UNIVERSITY   (United States)

Author keywords

balance; cerebellum; coding; dendrite; genesis; inhibition; model; simulatio n; spiking; synapse

Indexed keywords

ANIMAL CELL; ARTICLE; CALCIUM CONDUCTANCE; CALCIUM CURRENT; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; COMPUTER MODEL; CONTROLLED STUDY; DENDRITE; GUINEA PIG; MEMBRANE CURRENT; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; PURKINJE CELL; SOMATIC CELL; SPIKE WAVE; SYNAPSE; VOLTAGE CLAMP;

EID: 0031032024     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-01-00091.1997     Document Type: Article

References (11)

1. Albus JS (1971) A theory of cerebellar function. Math Biosci 10:25-61.
2. + current in pyramidal neurons from rat and cat somatosensory cortex. J Neurosci 13:660-673.
3. Bell AJ, Mainen ZF, Tsodyks M, Sejnowski TJ (1994) Balancing of conductances may explain irregular cortical spiking. INC Technical Report no. INC-9502. San Diego: University of California.
4. Bower JM, Woolston DC (1983) Congruence of spatial organization of tactile projections to granule cell and Purkinje cell layers of cerebellar hemispheres of the albino rat: vertical organization of cerebellar cortex. J Neurophysiol 49:745-766.
5. Bower JM (1996) Is the cerebellum sensory for motor's sake, or motor for sensory's sake: the view from the whiskers of a rat. Prog Brain Res, in press.
6. Braitenberg V (1993) The cerebellar network: attempt at a formalization of its structure. Network 4:11-17.
7. + current in cerebellar Purkinje cells has a single channel conductance distinct from the inactivating current. Soc Neurosci Abstr 20:63.
8. Sultan F, Ellisman MH, Bower JM (1995) Quantitative anatomical aspects of the inhibitory interneurons of the rat cerebellar molecular layer. A light and electron microscopic Golgi study. Soc Neurosci Abstr 21:1191.
9. Usher M, Stemmler M, Koch C, Olami Z (1994) Network amplification of local fluctuations causes high spike rate variability, fractal firing patterns and oscillatory local field potentials. Neural Comput 6:795-836.
10. Usowicz MM, Sugimori M, Cherksey B, Llińs R (1992) P-type calcium channels in the somata and dendrites of adult cerebellar Purkinje cells. Neuron 9:1185-1199.
11. Vincent P, Armstrong CM, Marty A (1992) Inhibitory synaptic currents in rat cerebellar Purkinje cells: modulation by postsynaptic depolarizations. J Physiol (Lond) 456:453-471.