The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice

Cardiovascular Research

Volumn 87, Issue 1, 2010, Pages 73-82

  Colussi, Claudia ^a   Berni, Roberta ^b   Rosati, Jessica ^c   Straino, Stefania ^c   Vitale, Serena ^c   Spallotta, Francesco ^c   Baruffi, Silvana ^b   Bocchi, Leonardo ^b   Delucchi, Francesca ^b   Rossi, Stefano ^b   Savi, Monia ^b   Rotili, Dante ^d   Quaini, Federico ^b   MacChi, Emilio ^b   Stilli, Donatella ^b   Musso, Ezio ^b   Mai, Antonello ^d   Gaetano, Carlo ^c   Capogrossi, Maurizio C ^c  

^a CENTRO CARDIOLOGICO MONZINO   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Arrhythmias; Connexins; Duchenne; Histone deacetylases; Ion channels

Indexed keywords

ACONITINE; CONNEXIN 32; CONNEXIN 37; CONNEXIN 40; CONNEXIN 43; CONNEXIN 45; GAP JUNCTION PROTEIN; SODIUM CHANNEL; SODIUM CHANNEL NAV1.5; VORINOSTAT; ANTIARRHYTHMIC AGENT; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; SCN5A PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DYSTROPHY; HEART CONDUCTION; HEART MUSCLE EXCITABILITY; HEART VENTRICLE ARRHYTHMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QRS COMPLEX; ACTION POTENTIAL; ANIMAL; ARRHYTHMIAS, CARDIAC; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; ELECTROCARDIOGRAPHY; EXERCISE; HEART MUSCLE CONDUCTION SYSTEM; HEART RATE; METABOLISM; MUSCULAR DYSTROPHY, DUCHENNE; PATHOPHYSIOLOGY; TELEMETRY; TIME; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ACONITINE; ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CONNEXINS; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY, AMBULATORY; HEART CONDUCTION SYSTEM; HEART RATE; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; MICE; MICE, INBRED MDX; MUSCULAR DYSTROPHY, DUCHENNE; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; RESTRAINT, PHYSICAL; SODIUM CHANNELS; TELEMETRY; TIME FACTORS;

EID: 77955165005     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq035     Document Type: Article

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