Conformational studies on the Δ8(E, Z)-sphingolipid desaturase from helianthus annuus with chiral fluoropalmitic acids as mechanistic probes

Journal of Organic Chemistry

Volumn 75, Issue 15, 2010, Pages 4975-4982

  Habel, Andreas ^a   Sperling, Petra ^b   Bartram, Stefan ^a   Heinz, Ernst ^b   Boland, Wilhelm ^a  

^a MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE CENTER; C-H ACTIVATION; CONFORMATIONAL STUDY; DESATURASE; DESATURATION; FLUORINE ATOMS; FLUOROALKENES; HELIANTHUS ANNUUS; HYDROGEN ATOMS; HYDROGEN REMOVAL; MECHANISTIC PROBES; RELATIVE RATIOS; SPHINGOLIPIDS; TRACE AMOUNTS; TRANSITION STATE; YEAST CELL;

ACTIVATION ANALYSIS; BYPRODUCTS; FLUORINE; ISOMERS; OLEFINS;

ACIDS;

ALIPHATIC COMPOUND; ALKENE DERIVATIVE; ENZYME; FLUORINE DERIVATIVE; HYDROGEN; PALMITIC ACID DERIVATIVE; SPHINGANINE; SPHINGOLIPID; SPHINGOLIPID DESATURASE; UNCLASSIFIED DRUG; OXIDOREDUCTASE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; ENZYME CONFORMATION; FLUORINATION; HYDROXYLATION; ISOMER; PROTEIN EXPRESSION; REACTION ANALYSIS; SUNFLOWER; YEAST CELL; CHEMISTRY; ENZYMOLOGY; MOLECULAR PROBE; PROTEIN CONFORMATION; STEREOISOMERISM;

HELIANTHUS; MOLECULAR PROBES; OXIDOREDUCTASES; PALMITIC ACIDS; PROTEIN CONFORMATION; STEREOISOMERISM;

EID: 77955149423     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo100542q     Document Type: Article

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