Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells

Brain Pathology

Volumn 20, Issue 5, 2010, Pages 966-975

  Mohan, Hema ^a,b   Krumbholz, Markus ^a,b   Sharma, Rakhi ^c   Eisele, Sylvia ^a,b   Junker, Andreas ^a,b   Sixt, Michael ^d   Newcombe, Jia ^e   Wekerle, Hartmut ^b   Hohlfeld, Reinhard ^a,b   Lassmann, Hans ^c   Meinl, Edgar ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d Medical University of Vienna   (Austria)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

extracellular matrix; inflammation; multiple sclerosis; neuroimmunology

Indexed keywords

BIGLYCAN; CHEMOKINE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 5; DECORIN; FIBRILLAR COLLAGEN; MONOCYTE CHEMOTACTIC PROTEIN 1; SCLEROPROTEIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNITY; INFLAMMATION; MULTIPLE SCLEROSIS; NEUROIMMUNOLOGY; POLYMERASE CHAIN REACTION;

BIGLYCAN; BRAIN; CELLS, CULTURED; CHEMOKINES; COLLAGEN TYPE I; DECORIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FIBRILLAR COLLAGENS; HUMANS; MONOCYTES; MULTIPLE SCLEROSIS; PROTEOGLYCANS; RNA, MESSENGER; T-LYMPHOCYTES; UP-REGULATION;

EID: 77955128811     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2010.00399.x     Document Type: Article

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