-
1
-
-
33748367018
-
A proposed classification of the immunological diseases
-
McGonagle D, McDermott MF: A proposed classification of the immunological diseases. PLOS Med 2006, 3:e297.
-
(2006)
PLOS Med
, vol.3
-
-
McGonagle, D.1
McDermott, M.F.2
-
2
-
-
68049119930
-
An integrated classification of pediatric inflammatory diseases, based on the concepts of autoinflammation and the immunological disease continuum
-
McGonagle D, Aziz A, Dickie, LJ, McDermott MF: An integrated classification of pediatric inflammatory diseases, based on the concepts of autoinflammation and the immunological disease continuum. Pediatr Res 2009, 65:38R-45R.
-
(2009)
Pediatr Res
, vol.65
-
-
McGonagle, D.1
Aziz, A.2
Dickie, L.J.3
McDermott, M.F.4
-
3
-
-
33745631232
-
The B30.2 domain of pyrin, the familial Mediterranean fever protien, interacts directly with caspase-1 to modulate IL-1beta production
-
Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL: The B30.2 domain of pyrin, the familial Mediterranean fever protien, interacts directly with caspase-1 to modulate IL-1beta production. Proc Natl Acad Sci U S A 2006, 103:9982-7.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9982-9987
-
-
Chae, J.J.1
Wood, G.2
Masters, S.L.3
Richard, K.4
Park, G.5
Smith, B.J.6
Kastner, D.L.7
-
4
-
-
33746876396
-
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
-
Goldbach-Mansky R, Dailey NJ, Canna SW, Gelabert A, Jones J, Rubin BI, Kim HJ, Brewer C, Zalewski C, Wiggs E, Hill S, Turner ML, Karp BI, Aksentijevich I, Pucino F, Penzak SR, Haverkamp MH, Stein L, Adams BS, Moore TL, Fuhlbrigge RC, Shaham B, Jarvis JN, O'Neil K, Vehe RK, Beitz LO, Gardner G, Hannan WP, Warren RW, Horn W, et al.: Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med 2006, 355:581-92.
-
(2006)
N Engl J Med
, vol.355
, pp. 581-592
-
-
Goldbach-Mansky, R.1
Dailey, N.J.2
Canna, S.W.3
Gelabert, A.4
Jones, J.5
Rubin, B.I.6
Kim, H.J.7
Brewer, C.8
Zalewski, C.9
Wiggs, E.10
Hill, S.11
Turner, M.L.12
Karp, B.I.13
Aksentijevich, I.14
Pucino, F.15
Penzak, S.R.16
Haverkamp, M.H.17
Stein, L.18
Adams, B.S.19
Moore, T.L.20
Fuhlbrigge, R.C.21
Shaham, B.22
Jarvis, J.N.23
O'Neil, K.24
Vehe, R.K.25
Beitz, L.O.26
Gardner, G.27
Hannan, W.P.28
Warren, R.W.29
Horn, W.30
more..
-
5
-
-
49449094179
-
Efficacy and safety of rilonacept (interleukin-1 trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies
-
Hoffman HM, Throne ML, Amar NJ, Sebai M, Kivitz AJ, Kavanaugh A, Weinstein SP, Belomestnov P, Yancopoulos GD, Stahl N, Mellis SJ: Efficacy and safety of rilonacept (interleukin-1 trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies. Arthritis Rheum 2008, 58:2443-52.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2443-2452
-
-
Hoffman, H.M.1
Throne, M.L.2
Amar, N.J.3
Sebai, M.4
Kivitz, A.J.5
Kavanaugh, A.6
Weinstein, S.P.7
Belomestnov, P.8
Yancopoulos, G.D.9
Stahl, N.10
Mellis, S.J.11
-
6
-
-
66649102432
-
Use of canakinumab in the cryopyrin-associated periodic syndrome
-
Canakinumab in CAPS Study Group
-
Lachmann HJ, Kone-Paut I, Kuemmerle-Deschner JB, Leslie KS, Hachulla E, Quartier P, Gitton X, Widmer A, Patel N, Hawkins PN; Canakinumab in CAPS Study Group: Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med 2009, 360:2416-25.
-
(2009)
N Engl J Med
, vol.360
, pp. 2416-2425
-
-
Lachmann, H.J.1
Kone-Paut, I.2
Kuemmerle-Deschner, J.B.3
Leslie, K.S.4
Hachulla, E.5
Quartier, P.6
Gitton, X.7
Widmer, A.8
Patel, N.9
Hawkins, P.N.10
-
8
-
-
39749175570
-
Successful treatment of resistant pseudogout with anakinra
-
McGonagle D, Tan AL, Madden J, Emery P, McDermott MF: Successful treatment of resistant pseudogout with anakinra. Arthritis Rheum 2008, 58:631-3.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 631-633
-
-
McGonagle, D.1
Tan, A.L.2
Madden, J.3
Emery, P.4
McDermott, M.F.5
-
9
-
-
70349402166
-
The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: Results of a placebo-controlled,monosequence crossover, non-randomised, single-blind pilot study
-
Terkeltaub R, Sundy JS, Schumacher HR, Murphy F, Bookbinder S, Biedermann S, Wu R, Mellis S, Radin A: The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled,monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis 2009, 68:1613-7.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1613-1617
-
-
Terkeltaub, R.1
Sundy, J.S.2
Schumacher, H.R.3
Murphy, F.4
Bookbinder, S.5
Biedermann, S.6
Wu, R.7
Mellis, S.8
Radin, A.9
-
10
-
-
0037231664
-
Cytokine traps: Multi-component, high affinity blockers of cytokine action
-
Economides AN, Carpenter LR, Rudge JS, Wong V, Koehler-Stec EM, Hartnett C, Pyles EA, Xu X, Daly TJ, Young MR, Fandl JP, Lee F, Carver S, McNay J, Bailey K, Ramakanth S, Hutabarat R, Huang TT, Radziejewski C, Yancopoulos GD, Stahl N: Cytokine traps: multi-component, high affinity blockers of cytokine action. Nat Med 2003, 9:47-52.
-
(2003)
Nat Med
, vol.9
, pp. 47-52
-
-
Economides, A.N.1
Carpenter, L.R.2
Rudge, J.S.3
Wong, V.4
Koehler-Stec, E.M.5
Hartnett, C.6
Pyles, E.A.7
Xu, X.8
Daly, T.J.9
Young, M.R.10
Fandl, J.P.11
Lee, F.12
Carver, S.13
McNay, J.14
Bailey, K.15
Ramakanth, S.16
Hutabarat, R.17
Huang, T.T.18
Radziejewski, C.19
Yancopoulos, G.D.20
Stahl, N.21
more..
-
11
-
-
0037231538
-
Setting the cytokine trap for autoimmunity
-
Dinarello CA: Setting the cytokine trap for autoimmunity. Nat Med 2003, 9:20-2.
-
(2003)
Nat Med
, vol.9
, pp. 20-22
-
-
Dinarello, C.A.1
-
12
-
-
33744762863
-
Hereditary auto-inflammatory disorders and biologics
-
Church LD, Churchman SM, Hawkins PN, McDermott MF: Hereditary auto-inflammatory disorders and biologics. Springer Semin Immunopathol 2006, 27:494-508.
-
(2006)
Springer Semin Immunopathol
, vol.27
, pp. 494-508
-
-
Church, L.D.1
Churchman, S.M.2
Hawkins, P.N.3
McDermott, M.F.4
-
13
-
-
29844442446
-
Systemic cytokine levels and the effects of etanercept in TNF receptor-associated periodic syndrome (TRAPS) involving a C33Y mutation in TNFRSF1A
-
Nowlan ML, Drewe E, Bulsara H, Esposito N, Robins RA, Tighe PJ, Powell RJ, Todd I: Systemic cytokine levels and the effects of etanercept in TNF receptor-associated periodic syndrome (TRAPS) involving a C33Y mutation in TNFRSF1A. Rheumatology 2006, 45:31-7.
-
(2006)
Rheumatology
, vol.45
, pp. 31-37
-
-
Nowlan, M.L.1
Drewe, E.2
Bulsara, H.3
Esposito, N.4
Robins, R.A.5
Tighe, P.J.6
Powell, R.J.7
Todd, I.8
-
14
-
-
34447308222
-
Failure of anti-TNF therapy in TNF receptor 1-associated periodic syndrome (TRAPS)
-
Jacobelli S, André M, Alexandra JF, Dodé C, Papo T: Failure of anti-TNF therapy in TNF receptor 1-associated periodic syndrome (TRAPS). Rheumatology 2007, 46:1211-2.
-
(2007)
Rheumatology
, vol.46
, pp. 1211-1212
-
-
Jacobelli, S.1
André, M.2
Alexandra, J.F.3
Dodé, C.4
Papo, T.5
-
15
-
-
59649101629
-
Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome
-
Nedjai B, Hitman GA, Quillinan N, Coughlan RJ, Church L, McDermott MF, Turner MD: Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome. Arthritis Rheum 2009, 60:619-25.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 619-625
-
-
Nedjai, B.1
Hitman, G.A.2
Quillinan, N.3
Coughlan, R.J.4
Church, L.5
McDermott, M.F.6
Turner, M.D.7
-
16
-
-
3843110981
-
Beneficial response to interleukin 1 receptor antagonist in TRAPS
-
Simon A, Bodar EJ, van der Hilst JC, van der Meer JW, Fiselier TJ, Cuppen MP, Drenth JP: Beneficial response to interleukin 1 receptor antagonist in TRAPS. Am J Med 2004, 117:208-10.
-
(2004)
Am J Med
, vol.117
, pp. 208-210
-
-
Simon, A.1
Bodar, E.J.2
Van Der Hilst, J.C.3
Van Der Meer, J.W.4
Fiselier, T.J.5
Cuppen, M.P.6
Drenth, J.P.7
-
17
-
-
43949128071
-
Persistent efficacy of anakinra in patients with tumor necrosis factor receptor-associated periodic syndrome
-
Gattorno M, Pelagatti MA, Meini A, Obici L, Barcellona R, Federici S, Buoncompagni A, Plebani A, Merlini G, Martini A: Persistent efficacy of anakinra in patients with tumor necrosis factor receptor-associated periodic syndrome. Arthritis Rheum 2008, 58:1516-20.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1516-1520
-
-
Gattorno, M.1
Pelagatti, M.A.2
Meini, A.3
Obici, L.4
Barcellona, R.5
Federici, S.6
Buoncompagni, A.7
Plebani, A.8
Merlini, G.9
Martini, A.10
-
18
-
-
66649121678
-
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
-
Aksentijevich I, Masters SL, Ferguson PJ, Dancey P, Frenkel J, van Royen-Kerkhoff A, Laxer R, Tedgard U, Cowen EW, Pham TH, Booty M, Estes JD, Sandler NG, Plass N, Stone DL, Turner ML, Hill S, Butman JA, Schneider R, Babyn P, El-Shanti HI, Pope E, Barron K, Bing X, Laurence A, Lee CC, Chapelle D, Clarke GI, Ohson K, Nicholson M, et al.: An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 2009, 360:2426-37.
-
(2009)
N Engl J Med
, vol.360
, pp. 2426-2437
-
-
Aksentijevich, I.1
Masters, S.L.2
Ferguson, P.J.3
Dancey, P.4
Frenkel, J.5
Van Royen-Kerkhoff, A.6
Laxer, R.7
Tedgard, U.8
Cowen, E.W.9
Pham, T.H.10
Booty, M.11
Estes, J.D.12
Sandler, N.G.13
Plass, N.14
Stone, D.L.15
Turner, M.L.16
Hill, S.17
Butman, J.A.18
Schneider, R.19
Babyn, P.20
El-Shanti, H.I.21
Pope, E.22
Barron, K.23
Bing, X.24
Laurence, A.25
Lee, C.C.26
Chapelle, D.27
Clarke, G.I.28
Ohson, K.29
Nicholson, M.30
more..
-
19
-
-
66649113371
-
An autoinflammatory disease due to homozygous deletion of the IL1RN locus
-
Reddy S, Jia S, Geoffrey R, Lorier R, Suchi M, Broeckel U, Hessner MJ, Verbsky J: An autoinflammatory disease due to homozygous deletion of the IL1RN locus. N Engl J Med 2009, 360:2438-44.
-
(2009)
N Engl J Med
, vol.360
, pp. 2438-2444
-
-
Reddy, S.1
Jia, S.2
Geoffrey, R.3
Lorier, R.4
Suchi, M.5
Broeckel, U.6
Hessner, M.J.7
Verbsky, J.8
-
20
-
-
34548436508
-
Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade
-
Allantaz F, Chaussabel D, Stichweh D, Bennett L, Allman W, Mejias A, Ardura M, Chung W, Wise C, Palucka K, Ramilo O, Punaro M, Banchereau J, Pascual V: Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade. J Exp Med 2007, 204:2131-44.
-
(2007)
J Exp Med
, vol.204
, pp. 2131-2144
-
-
Allantaz, F.1
Chaussabel, D.2
Stichweh, D.3
Bennett, L.4
Allman, W.5
Mejias, A.6
Ardura, M.7
Chung, W.8
Wise, C.9
Palucka, K.10
Ramilo, O.11
Punaro, M.12
Banchereau, J.13
Pascual, V.14
-
21
-
-
67650066800
-
Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis
-
Barnes MG, Grom AA, Thompson SD, Griffin TA, Pavlidis P, Itert L, Fall N, Sowders DP, Hinze CH, Aronow BJ, Luyrink LK, Srivastava S, Ilowite NT, Gottlieb BS, Olson JC, Sherry DD, Glass DN, Colbert RA: Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis. Arthritis Rheum 2009, 60:2102-12.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2102-2112
-
-
Barnes, M.G.1
Grom, A.A.2
Thompson, S.D.3
Griffin, T.A.4
Pavlidis, P.5
Itert, L.6
Fall, N.7
Sowders, D.P.8
Hinze, C.H.9
Aronow, B.J.10
Luyrink, L.K.11
Srivastava, S.12
Ilowite, N.T.13
Gottlieb, B.S.14
Olson, J.C.15
Sherry, D.D.16
Glass, D.N.17
Colbert, R.A.18
-
22
-
-
43949116263
-
The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis
-
Gattorno M, Piccini A, Lasigliè D, Tassi S, Brisca G, Carta S, Delfino L, Ferlito F, Pelagatti MA, Caroli F, Buoncompagni A, Viola S, Loy A, Sironi M, Vecchi A, Ravelli A, Martini A, Rubartelli A: The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2008, 58:1505-15.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1505-1515
-
-
Gattorno, M.1
Piccini, A.2
Lasigliè, D.3
Tassi, S.4
Brisca, G.5
Carta, S.6
Delfino, L.7
Ferlito, F.8
Pelagatti, M.A.9
Caroli, F.10
Buoncompagni, A.11
Viola, S.12
Loy, A.13
Sironi, M.14
Vecchi, A.15
Ravelli, A.16
Martini, A.17
Rubartelli, A.18
-
23
-
-
61749104104
-
The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis
-
Frosch M, Ahlmann M, Vogl T, Wittkowski H, Wulffraat N, Foell D, Roth J: The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2009, 60:883-91.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 883-891
-
-
Frosch, M.1
Ahlmann, M.2
Vogl, T.3
Wittkowski, H.4
Wulffraat, N.5
Foell, D.6
Roth, J.7
-
24
-
-
40749152243
-
Efficacy and safety of tocilizumab in pateints with systemic-onset juvenile idiopathic arthritis: A randomised, double-blind, placebo-controlled, withdrawal phase III trial
-
Yokota S, Imagawa T, Mori M, Miyamae T, Aihara Y, Takei S, Iwata N, Umebayashi H, Murata T, Miyoshi M, Tomiita M, Nishimoto N, Kishimoto T: Efficacy and safety of tocilizumab in pateints with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial. Lancet 2008, 371:998-1006.
-
(2008)
Lancet
, vol.371
, pp. 998-1006
-
-
Yokota, S.1
Imagawa, T.2
Mori, M.3
Miyamae, T.4
Aihara, Y.5
Takei, S.6
Iwata, N.7
Umebayashi, H.8
Murata, T.9
Miyoshi, M.10
Tomiita, M.11
Nishimoto, N.12
Kishimoto, T.13
-
25
-
-
34548163868
-
Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene
-
Cummings JR, Cooney R, Pathan S, Anderson CA, Barrett JC, Beckly J, Geremia A, Hancock L, Guo C, Ahmad T, Cardon LR, Jewell DP: Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene. Inflamm Bowel Dis 2007, 13:941-6.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 941-946
-
-
Cummings, J.R.1
Cooney, R.2
Pathan, S.3
Anderson, C.A.4
Barrett, J.C.5
Beckly, J.6
Geremia, A.7
Hancock, L.8
Guo, C.9
Ahmad, T.10
Cardon, L.R.11
Jewell, D.P.12
-
26
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Wellcome Trust Case Control Consortiuum
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC; Wellcome Trust Case Control Consortiuum, et al.: Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007, 39:830-2.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
Roberts, R.G.7
Nimmo, E.R.8
Cummings, F.R.9
Soars, D.10
Drummond, H.11
Lees, C.W.12
Khawaja, S.A.13
Bagnall, R.14
Burke, D.A.15
Todhunter, C.E.16
Ahmad, T.17
Onnie, C.M.18
McArdle, W.19
Strachan, D.20
Bethel, G.21
Bryan, C.22
Lewis, C.M.23
Deloukas, P.24
Forbes, A.25
Sanderson, J.26
Jewell, D.P.27
Satsangi, J.28
Mansfield, J.C.29
more..
-
27
-
-
58149159542
-
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
-
Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, Baba N, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Fortin PR, Wither JE, Sarfati M, Rutgeerts P, Rioux JD, Vermeire S, Hudson TJ, Franchimont D: Common variants in the NLRP3 region contribute to Crohn's disease susceptibility. Nat Genet 2009, 41:71-9.
-
(2009)
Nat Genet
, vol.41
, pp. 71-79
-
-
Villani, A.C.1
Lemire, M.2
Fortin, G.3
Louis, E.4
Silverberg, M.S.5
Collette, C.6
Baba, N.7
Libioulle, C.8
Belaiche, J.9
Bitton, A.10
Gaudet, D.11
Cohen, A.12
Langelier, D.13
Fortin, P.R.14
Wither, J.E.15
Sarfati, M.16
Rutgeerts, P.17
Rioux, J.D.18
Vermeire, S.19
Hudson, T.J.20
Franchimont, D.21
more..
-
28
-
-
58049204465
-
Autophagy and pattern recognition receptors in innate immunity
-
Delgado M, Singh S, De Haro S, Master S, Ponpuak M, Dinkins C, Ornatowski W, Vergne I, Deretic V: Autophagy and pattern recognition receptors in innate immunity. Immunol Rev 2009, 227:189-202.
-
(2009)
Immunol Rev
, vol.227
, pp. 189-202
-
-
Delgado, M.1
Singh, S.2
De Haro, S.3
Master, S.4
Ponpuak, M.5
Dinkins, C.6
Ornatowski, W.7
Vergne, I.8
Deretic, V.9
-
30
-
-
23444439667
-
IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients
-
Stack JH, Beaumont K, Larsen PD, Straley KS, Henkel GW, Randle JC, Hoffman HM: IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients. J Immunol 2005, 175:2630-34.
-
(2005)
J Immunol
, vol.175
, pp. 2630-2634
-
-
Stack, J.H.1
Beaumont, K.2
Larsen, P.D.3
Straley, K.S.4
Henkel, G.W.5
Randle, J.C.6
Hoffman, H.M.7
|