Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase ε in the presence of replication protein A and proliferating-cell nuclear antigen

Biochemical Journal

Volumn 429, Issue 3, 2010, Pages 573-582

  Locatelli, Giada A ^a   Pospiech, Helmut ^b,c   Tanguy Le Gac, Nicolas ^a   Van Loon, Barbara ^d   Hubscher, Ulrich ^d   Parkkinen, Sinikka ^e   Syväoja, Juhani E ^e   Villani, Giuseppe ^a  

^a UNIVERSITÉ PAUL SABATIER   (France)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c UNIVERSITY OF OULU   (Finland)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

7,8 dihydro 8 oxoguanine; DNA damage; DNA polymerase; DNA replication; Proliferating cell nuclear antigen (PCNA); Replication protein A (RPA)

Indexed keywords

8-OXOGUANINE; DNA DAMAGE; DNA POLYMERASE; DNA REPLICATIONS; PROLIFERATING-CELL NUCLEAR ANTIGEN (PCNA); REPLICATION PROTEIN A;

ANTIGENS; DNA; ELONGATION; POLYMERS; PROTEINS;

GENES;

8 HYDROXYGUANINE; CYCLINE; DNA DIRECTED DNA POLYMERASE EPSILON; PRIMER DNA; REPLICATION FACTOR A; SINGLE STRANDED DNA BINDING PROTEIN; 8-HYDROXYGUANINE; DNA; DNA DIRECTED DNA POLYMERASE; DRUG DERIVATIVE; GUANINE;

ARTICLE; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; GENE INSERTION; HUMAN; IN VITRO STUDY; MODULATION; PRIORITY JOURNAL; HELA CELL; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

EUKARYOTA;

BASE SEQUENCE; DNA; DNA DAMAGE; DNA-DIRECTED DNA POLYMERASE; GUANINE; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PROLIFERATING CELL NUCLEAR ANTIGEN; REPLICATION PROTEIN A;

EID: 77955065200     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100405     Document Type: Article

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