Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer

Oncogene

Volumn 24, Issue 51, 2005, Pages 7630-7634

  Oliveira, Carla ^a   Velho, Sérgia ^a   Domingo, Enric ^b   Preto, Ana ^a   Hofstra, Robert M W ^c   Hamelin, Richard ^d   Yamamoto, Hiroyuki ^e   Seruca, Raquel ^a,f   Schwartz Jr , Simo ^b  

^a UNIVERSITY OF PORTO   (Portugal)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d FONDATION JEAN DAUSSET CEPH   (France)

^e SAPPORO MEDICAL UNIVERSITY   (Japan)

^f University of Porto   (Portugal)

Author keywords

BRAF; Colorectal cancer; Gastric cancer; KRAS; MSI; RASSF1A promoter methylation

Indexed keywords

B RAF KINASE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A;

ANALYTIC METHOD; ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DEMETHYLATION; DNA SEQUENCE; EPIGENETICS; GASTROINTESTINAL TUMOR; HUMAN; HUMAN TISSUE; METHYLATION; MUTATION; PATHOGENESIS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STOMACH TUMOR;

CARCINOMA; COLORECTAL NEOPLASMS; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; GENES, RAS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICROSATELLITE REPEATS; MUTATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS B-RAF; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 27844458489     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208906     Document Type: Article

References (24)

1. Brennetot C, Duval A, Hamelin R, Pinto M, Oliveira C, Seruca R and Schwartz Jr S. (2003). Gastroenterology, 125, 1282.
2. Byun D, Lee M, Chae K, Ryu B and Chi S. (2002). Cancer Res., 61, 7034-7038.
3. Dammann R, Li C, Yoon JH, Chin PL, Bates S and Pfeifer GP. (2000). Nat. Genet., 25, 315-319.
4. Dammann R, Schagdarsurengin U, Strunnikova M, Rastetter M, Seidel C, Liu L, Tommasi S and Pfeifer GP. (2003). Histol. Histopathol., 18, 665-677.
5. De Caceres II, Battagli C, Esteller M, Herman JG, Dulaimi E, Edelson MI, Bergman C, Ehya H, Eisenberg BL and Cairns P. (2004). Cancer Res., 64, 6476-6481.
6. Deng G, Bell I, Crawley S, Gum J, Terdiman JP, Allen BA, Truta B, Sleisenger MH and Kim YS. (2004). Clin. Cancer Res., 10, 191-195.
7. Domingo E, Espin E, Armengol M, Oliveira C, Pinto M, Duval A, Brennetot C, Seruca R, Hamelin R, Yamamoto H and Schwartz Jr S. (2004a). Genes Chromosomes Cancer, 39, 138-142.
8. Domingo E, Laiho P, Ollikainen M, Pinto M, Wang L, French AJ, Westra J, Frebourg T, Espin E, Armengol M, Hamelin R, Yamamoto H, Hofstra RM, Seruca R, Lindblom A, Peltomaki P, Thibodeau SN, Aaltonen LA and Schwartz Jr S. (2004b). J. Med. Genet., 41, 664-668.
9. Koinuma K, Shitoh K, Miyakura Y, Furukawa T, Yamashita Y, Ota J, Ohki R, Choi YL, Wada T, Konishi F, Nagai H and Mano H. (2004). Int. J. Cancer, 108, 237-242.
10. Lerman MI and Minna JD. (2000). Cancer Res., 60, 6116-6133.
11. McGivern A, Wynter CV, Whitehall VL, Kambara T, Spring KJ, Walsh MD, Barker MA, Arnold S, Simms LA, Leggett BA, Young J and Jass JR. (2004). Fam. Cancer, 3, 101-107.
12. Oliveira C, Pinto M, Duval A, Brennetot C, Domingo E, Espin E, Armengol M, Yamamoto H, Hamelin R, Seruca R and Schwartz Jr S. (2003). Oncogene, 22, 9192-9196.
13. Oliveira C, Westra JL, Arango D, Ollikainen M, Domingo E, Ferreira A, Velho S, Niessen R, Lagerstedt K, Alhopuro P, Laiho P, Veiga I, Teixeira MR, Ligtenberg M, Kleibeuker JH, Sijmons RH, Plukker JT, Imai K, Lage P, Hamelin R, Albuquerque C, Schwartz Jr S, Lindblom A, Peltomaki P, Yamamoto H, Aaltonen LA, Seruca R and Hofstra RM. (2004). Hum. Mol. Genet., 13, 2303-2311.
14. Ortiz-Vega S, Khokhlatchev A, Nedwidek M, Zhang XF, Dammann R, Pfeifer GP and Avruch J. (2002). Oncogene, 21, 1381-1390.
15. Pfeifer GP, Yoon JH, Liu L, Tommasi S, Wilczynski SP and Dammann R. (2002). Biol. Chem., 383, 907-914.
16. Rajagopalan H, Bardelli A, Lengauer C, Kinzler KW, Vogelstein B and Velculescu VE. (2002). Nature, 418, 934.
17. Reifenberger J, Knobbe CB, Sterzinger AA, Blaschke B, Schulte KW, Ruzicka T and Reifenberger G. (2004). Int. J. Cancer, 109, 377-384.
18. Shivakumar L, Minna J, Skamaki T, Pestell R and White MA. (2002). Mol. Cell. Biol., 22, 4309-4318.
19. Umar A, Risinger JI, Hawk ET and Barrett JC. (2004). Nat. Rev. Cancer, 4, 153-158.
20. Van Engeland M, Roemen G, Brink M, Pachen M, Weijenberg M, Bruïne A, Arends J, Brandt P, Goeij A and Herman J. (2002). Oncogene, 21, 3792-3795.
21. Vos MD, Ellis CA, Bell A, Birrer MJ and Clark GJ. (2000). J. Biol. Chem., 275, 35669-35672.
22. Williams JG, Drugan JK, Yi GS, Clark GJ, Der CJ and Campbell SL. (2000). J. Biol. Chem., 275, 22172-22179.
23. Xing M, Cohen Y, Mambo E, Tallini G, Udelsman R, Ladenson PW and Sidransky D. (2004). Cancer Res., 64, 1664-1668.
24. Yuen ST, Davies H, Chan TL, Ho JW, Bignell GR, Cox C, Stephens P, Edkins S, Tsui WW, Chan AS, Futreal PA, Stratton MR, Wooster R and Leung SY. (2002). Cancer Res., 62, 6451-6455.