Flat-type colorectal advanced adenomas (laterally spreading tumors) have different genetic and epigenetic alterations from protruded-type advanced adenomas

Modern Pathology

Volumn 20, Issue 1, 2007, Pages 139-147

  Takahashi, Taiga ^a   Nosho, Katsuhiko ^a,c   Yamamoto, Hiroyuki ^a   Mikami, Masashi ^a   Taniguchi, Hiroaki ^a   Miyamoto, Nobuki ^a   Adachi, Yasushi ^a   Itoh, Fumio ^b   Imai, Kohzoh ^c   Shinomura, Yasuhisa ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

Advanced adenoma; Colorectal cancer; Flat type colorectal adenoma; KRAS; Laterally spreading tumor; MethyLight

Indexed keywords

B RAF KINASE; BETA CATENIN; K RAS PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MLH1; PROTEIN P16;

ADULT; ADVANCED CANCER; AGED; AMINO ACID SUBSTITUTION; ARTICLE; COLON; COLORECTAL ADENOMA; CONTROLLED STUDY; DEVICE; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; MALE; MUTATIONAL ANALYSIS; ONCOGENE K RAS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENINE; ADENOMA; AGED; BETA CATENIN; CARRIER PROTEINS; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA MUTATIONAL ANALYSIS; DNA REPAIR ENZYMES; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEINS;

EID: 33845696275     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.3800722     Document Type: Article

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