Pharmacokinetics and toxicodynamics of pralidoxime effects on paraoxon-induced respiratory toxicity

Toxicological Sciences

Volumn 116, Issue 2, 2010, Pages 660-672

  Houzé, Pascal ^a,b   Mager, Donald E ^c   Risède, Patricia ^b   Baud, Frédéric J ^b,d  

^a SAINT LOUIS HOSPITAL   (France)

^b INSERM   (France)

^c UNIVERSITY AT BUFFALO   (United States)

^d HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Diethylparaoxon; Pharmacokinetic; Plethymography; Pralidoxime; Rat; Toxycodynamic

Indexed keywords

CHOLINESTERASE; PARAOXON; PRALIDOXIME; ANTIDOTE; INSECTICIDE;

ANIMAL MODEL; ARTICLE; BREATHING RATE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REACTIVATION; IN VITRO STUDY; IN VIVO STUDY; LUNG TOXICITY; MALE; NONHUMAN; PLETHYSMOGRAPHY; RAT; ANIMAL; BIOLOGICAL MODEL; BLOOD; BREATHING; DRUG EFFECTS; ENZYMOLOGY; LEUKOCYTE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIDOTES; CHOLINESTERASES; INSECTICIDES; LEUKOCYTES; MALE; MODELS, BIOLOGICAL; PARAOXON; PRALIDOXIME COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION;

EID: 77955061383     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq152     Document Type: Article

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