Expression of two cytochrome P450 aromatase genes is regulated by endocrine disrupting chemicals in rare minnow Gobiocypris rarus juveniles

Comparative Biochemistry and Physiology - C Toxicology and Pharmacology

Volumn 152, Issue 3, 2010, Pages 313-320

  Wang, Jingjing ^a   Liu, Xiaolin ^a   Wang, Houpeng ^a   Wu, Tingting ^a   Hu, Xiaoqi ^a   Qin, Fang ^a   Wang, Zaizhao ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Aromatase; Cyp19a1; Endocrine disrupting chemicals; Gobiocypris rarus; Real time PCR

Indexed keywords

4 NONYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; AROMATASE; AROMATIC HYDROCARBON RECEPTOR; CCAAT ENHANCER BINDING PROTEIN; CLOFIBRATE; CYTOCHROME P450; ENDOCRINE DISRUPTOR; ETHINYLESTRADIOL; GLUCOCORTICOID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOIC ACID RECEPTOR; STEROIDOGENIC FACTOR 1;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN; CONTROLLED STUDY; DOWN REGULATION; ESTROGEN RESPONSIVE ELEMENT; FISH; GENE EXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; GOBIOCYPRIS RARUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

CYPRINIDAE; GOBIOCYPRIS RARUS;

EID: 77955050306     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpc.2010.05.007     Document Type: Article

References (31)

1. Brucker-Davis F., Thayer K., Colborn T. Significant effects of endogenous hormonal changes in humans: considerations for low dose testing. Environ. Health Perspect. 2001, 109:21-26.
2. Cheshenko K., Brion F., Page Y.L., Hinfray N., Pakdel F., Kah O., Segner H., Eggen R.I.L. Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor. Toxicol. Sci. 2007, 96(2):255-267.
3. Cheshenko K., Pakdel F., Segner H., Kah O., Eggen R.I.L. Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish. Gen. Comp. Endocrinol. 2008, 155:31-62.
4. Choi J.Y., Park J.G., Jeong H.B., Lee Y.D., Takemura A., Kim S.J. Molecular cloning of cytochrome P450 aromatases in the protogynous wrasse, Halichoeres tenuispinis. Comp. Biochem. Physiol. B. 2005, 141:49-59.
5. Conley A., Hinshelwood M. Mammalian aromatases. Reproduction 2001, 121:685-695.
6. Gelinas D., Pitoc G.A., Callard G.V. Isolation of a goldfish brain cytochrome P450 aromatase cDNA: mRNA expression during the seasonal cycle and after steroid treatment. Mol. Cell. Endocrinol. 1998, 138:81-93.
7. Goksoyr A. Endocrine disruptors in the marine environment: mechanisms of toxicity and their influence on reproductive processes in fish. J. Toxicol. Environ. Health A 2006, 69:175-184.
8. Hallgren S., Olsen K.H. Effects on Guppy brain aromatase activity following short-term steroid and 4-nonylphenol exposures. Environ. Toxicol. 2010, 25:261-271.
9. Hayashi H., Nishimoto A., Oshima N., Iwamuro S. Expression of the estrogen receptor alpha gene in the anal fin of Japanese medaka, Oryzias latipes, by environmental concentration of bisphenol A. J. Toxicol. Sci. 2007, 32:91-96.
10. Hinfray N., Palluel O., Turies C., Cousin C., Porcher J.M., Brion F. Brain and gonadal aromatase as potential targets of endocrine disrupting chemicals in a model species, the zebrafish (Danio rerio). Environ. Toxicol. 2006, 21:332-337.
11. Huang H., Leung L.K. Bisphenol A downregulates CYP19 transcription in JEG-3 cells. Toxicol. Lett. 2009, 189:248-252.
12. Kazeto Y., Ijiri S., Place A.R., Zohar Y., Trant J.M. The 5'-flanking regions of CYP19A1 and CYP19A2 in zebrafish. Biochem. Biophys. Res. Commun. 2001, 288:503-508.
13. Kazeto Y., Place A.R., Trant J.M. Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles. Aquat. Toxicol. 2004, 69:25-34.
14. Kishida M., McLellan M., Miranda J.A., Callard G.V. Estrogen and xenoestrogens upregulate the brain aromatase isoform (P450aromB) and perturb markers of early development in zebrafish (Danio rerio). Comp. Biochem. Physiol. B. 2001, 129:261-268.
15. Kortner T.M., Mortensen A.S., Hansen M.D., Arukwe A. Neural aromatase transcript and protein levels in Atlantic salmon (Salmo salar) are modulated by the ubiquitous water pollutant, 4-nonylphenol. Gen. Comp. Endocrinol. 2009, 164:91-99.
16. Lee Y.M., Seo J.S., Kim I.C., Yoon Y.D., Lee J.S. Endocrine disrupting chemicals (bisphenol A, 4-nonylphenol, 4-tert-octylphenol) modulate expression of two distinct cytochrome P450 aromatase genes differently in gender types of the hermaphroditic fish Rivulus marmoratus. Biochem. Biophys. Res. Commun. 2006, 345:894-903.
17. Liu Y., Wang J., Wei Y., Zhang H., Dai J. Molecular characterization of cytochrome P450 1A and 3A and the effects of perfluorooctanoic acid on their mRNA levels in rare minnow (Gobiocypris rarus) gills. Aquat. Toxicol. 2008, 88:183-190.
18. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
19. Lyssimachou A., Jenssen B.M., Arukwe A. Brain cytochrome P450 aromatase gene isoforms and activity levels in Atlantic salmon after waterborne exposure to nominal environmental concentrations of the pharmaceutical enhinylestradiol and antifoulant tributyltin. Toxicol. Sci. 2006, 91:82-92.
20. Ma L., Li D., Wang J., He J., Yin Z. Effects of adrenergic agonists on the extrahepatic expression of vitellogenin Ao1 in heart and brain of the Chinese rare minnow (Gobiocypris rarus). Aquat. Toxicol. 2009, 91:19-25.
21. Ohtake F., Takeyama K.-i., Matsumoto T., Kitagawa H., Yamamoto Y., Nohara K., Tohyama C., Krust A., Mimura J., Chambon P., Yanagisawa J., Fujii-Kuriyama Y., Kato S. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 2003, 423:545-550.
22. Orford R.L., Robinson C., Haydon J.M., Patient R.K., Guille M.J. The maternal CCAAT box transcription factor which controls GATA-2 expression is novel and developmentally regulated and contains a double-stranded-RNA-binding subunit. Mol. Cell. Biol. 1998, 18:5557-5566.
23. Quesada I., Fuentes E., Viso-Leon M.C., Soria B., Ripoll C., Nadal A. Low doses of the endocrine disruptor bisphenol-A and the native hormone 17 β-estradiol rapidly activate transcription factor CREB. FASEB J. 2002, 16:1671-1673.
24. Segner H., Caroll K., Fenske M., Janssen C.R., Maack G., Pascoe D., Schafers C., Vandenbergh G.F., Watts M., Wenzel A. Identification of endocrine-disrupting effects in aquatic vertebrates and invertebrates: report from the European IDEA project. Ecotoxicol. Environ. Saf. 2003, 54:302-314.
25. Simpson E.R., Clyne C., Rubin G., Boon Robertson W.C.K., Britt K., Speed C., Jones M. Aromatase-a brief overview. Annu. Rev. Physiol. 2002, 64:93-127.
26. Tamura K., Dudley J., Nei M., Kumar S. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol. Biol. Evol. 2007, 24:1596-1599.
27. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., Higgins D.G. The ClustalX Windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 1997, 25:4876-4882.
28. Welshons W.V., Nagel S.C., vom Saal F.S. Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology 2006, 147:S56-S69.
29. Zha J.M., Sun L.W., Spear P.A., Wang Z.J. Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus). Ecotox. Environ. Safe. 2008, 71:390-399.
30. Zha J.M., Wang Z.J., Wang N., Ingersoll C. Histological alternation and vitellogenin induction in adult rare minnow (Gobiocypris rarus) after exposure to ethynylestradiol and nonylphenol. Chemosphere 2007, 77:488-495.
31. Zhong X.P., Xu Y., Liang Y., Liao T., Wang J.W. The Chinese rare minnow (Gobiocypris rarus) as an in vivo model for endocrine disruption in freshwater teleosts: a full life-cycle test with diethylstilbestrol. Aquat. Toxicol. 2005, 71:85-95.