Epidemiological, demographic, and molecular characteristics of laboratory-confirmed pandemic influenza a (H1N1) virus infection in Turkey, May 15-November 30, 2009

Japanese Journal of Infectious Diseases

Volumn 63, Issue 4, 2010, Pages 239-245

  Ertek, Mustafa ^a   Durmaz, Riza ^a   Guldemir, Dilek ^a   Altas, A Basak ^a   Albayrak, Nurhan ^a   Korukluoglu, Gulay ^a  

^a Refik Saydam National Public Health Agency   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS HEMAGGLUTININ; VIRUS RNA; VIRUS SIALIDASE; HEMAGGLUTININ FUSOGENIC PEPTIDE, INFLUENZA VIRUS; NA PROTEIN, INFLUENZA A VIRUS; SIALIDASE; VIRUS PROTEIN;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; GENE MUTATION; HUMAN; INFANT; INFLUENZA A (H1N1); LABORATORY DIAGNOSIS; MALE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANDEMIC INFLUENZA; PRESCHOOL CHILD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; SEQUENCE ANALYSIS; TURKEY (REPUBLIC); VIRUS CHARACTERIZATION; VIRUS ISOLATION; VIRUS MUTATION; VIRUS STRAIN; DNA SEQUENCE; GENETICS; INCIDENCE; INFLUENZA VIRUS A H1N1; INFLUENZA, HUMAN; ISOLATION AND PURIFICATION; MIDDLE AGED; MISSENSE MUTATION; NEWBORN; SEQUENCE HOMOLOGY; SEX RATIO; TURKEY; VERY ELDERLY; VIROLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; FEMALE; HEMAGGLUTININS, VIRAL; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MALE; MIDDLE AGED; MUTATION, MISSENSE; NEURAMINIDASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; SEX DISTRIBUTION; TURKEY; VIRAL PROTEINS; YOUNG ADULT;

EID: 77955002068     PISSN: 13446304     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Gatherer, D. (2009): The 2009 H1N1 influenza outbreak in its historical context. J. Clin. Virol., 45, 174-178.
2. Dawood, F.S., Jain, S., Finelli, L., et al. (2009): Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N. Engl. J. Med., 360, 2605-2615.
3. Scalera, N.M. and Mossad, S.B. (2009): The first pandemic of the 21st century: a review of the 2009 pandemic variant influenza A (H1N1) virus. Postgrad. Med., 121, 43-47.
4. Chang, L.-Y., Shih, S.-R., Shao, P.-L., et al. (2009): Novel swine-origin influenza virus A (H1N1): the first pandemic of 21st century. J. Formos. Med. Assoc, 108, 526-532.
5. World Health Organization (2009): Pandemic (H1N1) 2009-update 77. Online at .
6. Kelly, H. and Grant, K. (2009): Interim analysis of pandemic influenza (H1N1) 2009 in Australia: surveillance trends, age of infection and effectiveness of seasonal vaccination. Euro Surveill., 14(3l):pii= 19288.
7. Centers for Disease Control and Prevention (2009): 2009 pandemic influenza A (H1N1) virus infections-Chicago, Illinois, April-July 2009. Morb. Mortal. Wkly. Rep., 58, 913-918.
8. Kelly, H.A., Grant, K.A., Williams, S., et al. (2009): Epidemio-logical characteristics of pandemic influenza H1N1 2009 and seasonal influenza infection. Med. J. Aust., 191, 146-149.
9. Boni, M.F., Manh, B.H., Thai, P.Q., et al. (2009): Modelling the progression of pandemic influenza A (H1N1) in Vietnam and the opportunities for reassortment with other influenza viruses. BMC. Med., 7, 43.
10. Schnitzler, S.U. and Schnitzler, P. (2009): An update on swine-origin influenza virus A/H1N1: a review. Virus Genes, 39, 279-292.
11. Ciblak, M.A., Albayrak, N., Odabas, Y., et al. (2009): Cases of influenza A(HlNl)v reported in Turkey, May-July 2009. Euro Surveill., 14(33):pii= 19313.
12. World Health Organization (2009): Centers for Disease Control and Prevention pyrosequencing assay to detect H275Y mutation in the neuraminidase of novel A (H1N1) viruses. Online at .
13. Centers for Disease Control and Prevention (2009): Update: drug susceptibility of swine-origin influenza A (H1N1) viruses, April 2009. Morbid. Mortal. Wkly. Rep., 58, 433-435.
14. Deyde, V.M., Okomo-Adhiambo, M., Sheu, T.G., et al. (2009): Pyrosequencing as a tool to detect molecular markers of resistance to neuraminidase inhibitors in seasonal influenza A viruses. Antiviral Res., 81, 16-24.
15. Cao, B., Li, Z.-W., Mao, Y., et al. (2009): Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in China. N. Engl. J. Med., 361, 2507-2517.
16. Wiley, D.C. and Skehel, J.J. (1987): The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu. Rev. Biochem., 56, 365-394.
17. Matrosovich, M., Tuzikov, A., Bovin, N., et al. (2000): Early alterations of the receptor-binding properties of HI, H2, and H3 a-vian influenza virus hemagglutinins after their introduction into mammals. J. Virol., 74, 8502-8512.
18. World Health Organization (2009): Pandemic (H1N1) 2009-up-date 78. Online at .
19. World Health Organization (2010): Preliminary review of D222G amino acid substitution in the haemagglutinin of pandemic influenza A (H1N1) 2009 viruses. Wkly. Epidemiol. Rec, 85, 21-28.
20. Kilander, A., Rykkvin, R., Dudman, S. G., et al. (2010): Observed association between the HA1 mutation D222G in the 2009 pandemic influenza A(H1N1) virus and severe clinical outcome, Norway 2009-2010. Euro Surveill., 15(9):pii= 19498.
21. Chen, H., Cheung, C.L., Tai, H., et al. (2009): Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China. Emerg. Infect. Dis., 15, 1970-1972.
22. Kiso, M., Mitamura, K., Sakai-Tagawa, Y., et al. (2004): Resistant influenza A viruses in children treated with oseltamivir: descriptive study. Lancet, 364, 759-765.
23. World Health Organization (2009): Pandemic (H1N1) 2009 briefing note 1. Viruses resistant to oseltamivir (Tamiflu) identified. 8 July 2009. Online at .
24. Hall, R.J., Peacey, M.P., Ralston, J.C., et al. (2009): Pandemic influenza A(HlNl)v viruses currently circulating in New Zealand are sensitive to oseltamivir. Euro. Surveill., 14(30):pii= 19282.
25. Rotanov, M., Grebennikova, T.V., Burtseva, E.I., et al. (2008): Molecular and genetic analysis of influenza A viruses isolated in Russia, based on the neuraminidase and M2 protein gene sequence. Mol. Gen. Mikrobiol. Virusol., 2, 27-32.
26. Baz, M., Abed, Y., Papenburg, J., et al. (2009): Emergence of oseltamivir-resistant pandemic H1N1 virus during propylaxis. N. Engl. J. Med., 361, 2296-2297.
27. Centers for Disease Control and Prevention (2009): Oseltamivir-resistant 2009 pandemic influenza A (H1N1) virus infection in two summer campers receiving prophylaxis-North Carolina, 2009. Morbid. Mortal. Wkly. Rep., 58, 969-972.