Pathophysiology of ARDS

Respiratory System and Artificial Ventilation

Volumn , Issue , 2008, Pages 101-117

  Chiumello, D ^a   Valente Barbas, C S ^b   Pelosi, P ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77954982783     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-88-470-0765-9_7     Document Type: Chapter

References (67)

1. Ware LB, Matthay MA (2000) The acute respiratory distress syndrome. N Engl J Med 342:1334-1349
2. Bernard GR, Artigas A, Brigham KL et al (1994) Report of the American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes and clinical trial coordination. The Consensus Committee. Intensive Care Med 20:225-232
3. Haataja R, Ramet M, Marttila R et al (2000) Surfactant proteins A and B as interactive genetic determinants of neonatal respiratory distress syndrome. Hum Mol Genet 9:2751-2760
4. Lin Z, Pearson C, Chinchilli V et al (2000) Polymorphisms of human SP-A, SP-B, and SP-D genes: association of SP-B Thr131Ile with ARDS. Clin Genet 58:181-191
5. Wong HR (2002) ARDS. The future. Crit Care Clin 18:177-196
6. Atabai K, Matthay MA (2002) The pulmonary physician in critical care. 5: Acute lung injury and the acute respiratory distress syndrome: definitions and epidemiology. Thorax 57:452-458
7. Matthay MA, Wiener-Kronish JP (1990) Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 142:1250-1257
8. Bellingan GJ (2002) The pulmonary physician in critical care 6: The pathogenesis of ALI/ARDS. Thorax 57:540-546
9. Gregory TJ, Longmore WJ, Moxley MA et al (1991) Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J Clin Invest 88:1976-1981
10. Pison U, Obertacke U, Seeger W et al (1992) Surfactant protein A (SP-A) is decreased in acute parenchymal lung injury associated with polytrauma. Eur J Clin Invest 22:712-718
11. Greene KE, Wright JR, Steinberg KP et al (1999) Serial changes in surfactant-associated proteins in lung and serum before and after onset of ARDS. Am J Respir Crit Care Med 160:1843-1850
12. Doyle IR, Bersten AD, Nicholas TE (1997) Surfactant proteins-A and-B are elevated in plasma of patients with acute respiratory failure. Am J Respir Crit Care Med 156:1217-1229
13. Cheng IW, Ware LB, Greene KE et al (2003) Prognostic value of surfactant proteins A and D in patients with acute lung injury. Crit Care Med 31:20-27
14. Rasaiah VP, Malloy JL, Lewis JF et al (2003) Early surfactant administration protects against lung dysfunction in a mouse model of ARDS. Am J Physiol Lung Cell Mol Physiol 284:L783-L790
15. Larsen GL, McCarthy K, Webster RO et al (1980) A differential effect of C5a and C5a des Arg in the induction of pulmonary inflammation. Am J Pathol 100:179-192
16. Steinberg KP, Milberg JA, Martin TR et al (1994) Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome. Am J Respir Crit Care Med 150:113-122
17. Weiland JE, Davis WB, Holter JF et al (1986) Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance. Am Rev Respir Dis 133:218-225
18. Sibille Y, Reynolds HY (1990) Macrophages and polymorphonuclear neutrophils in lung defense and injury. Am Rev Respir Dis 141:471-501
19. Suter PM, Suter S, Girardin E et al (1992) High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am Rev Respir Dis 145:1016-1022
20. Christner P, Fein A, Goldberg S et al (1985) Collagenase in the lower respiratory tract of patients with adult respiratory distress syndrome. Am Rev Respir Dis 131:690-695
21. Abraham E. (2003) Neutrophils and acute lung injury. Crit Care Med 31:S195-S199
22. Martin TR, Nakamura M, Matute-Bello G (2003) The role of apoptosis in acute lung injury. Crit Care Med 31:S184-S188
23. Martin TR, Pistorese BP, Hudson LD et al (1991) The function of lung and blood neutrophils in patients with the adult respiratory distress syndrome. Implications for the pathogenesis of lung infections. Am Rev Respir Dis 144:254-262
24. Pittet JF, Mackersie RC, Martin TR et al (1997) Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med 155:1187-1205
25. Hammerschmidt DE, Weaver LJ, Hudson LD et al (1980) Association of complement activation and elevated plasma-C5a with adult respiratory distress syndrome. Pathophysiological relevance and possible prognostic value. Lancet 1:947-949
26. Duchateau J, Haas M, Schreyen H et al (1984) Complement activation in patients at risk of developing the adult respiratory distress syndrome. Am Rev Respir Dis 130:1058-1064
27. Webster RO, Larsen GL, Mitchell BC et al (1982) Absence of inflammatory lung injury in rabbits challenged intravascularly with complement-derived chemotactic factors. Am Rev Respir Dis 125:335-340
28. Mathru M, Rooney MW, Dries DJ et al (1994) Urine hydrogen peroxide during adult respiratory distress syndrome in patients with and without sepsis. Chest 105:232-236
29. Cochrane CG, Spragg R, Revak SD (1983) Pathogenesis of the adult respiratory distress syndrome. Evidence of oxidant activity in bronchoalveolar lavage fluid. J Clin Invest 71:754-761
30. Bunnell E, Pacht ER (1993) Oxidized glutathione is increased in the alveolar fluid of patients with the adult respiratory distress syndrome. Am Rev Respir Dis 148:1174-1178
31. Meduri GU, Kohler G, Headley S et al (1995) Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome. Chest 108:1303-1314
32. Hyers TM, Tricomi SM, Dettenmeier PA et al (1991) Tumor necrosis factor levels in serum and bronchoalveolar lavage fluid of patients with the adult respiratory distress syndrome. Am Rev Respir Dis 144:268-271
33. Windsor AC, Walsh CJ, Mullen PG et al (1993) Tumor necrosis factor-alpha blockade prevents neutrophil CD18 receptor upregulation and attenuates acute lung injury in porcine sepsis without inhibition of neutrophil oxygen radical generation. J Clin Invest 91:1459-1468
34. Berthiaume Y, Albertine KH, Grady M et al (1989) Protein clearance from the air spaces and lungs of unanesthetized sheep over 144 h. J Appl Physiol 67:1887-1897
35. Pugin J, Ricou B, Steinberg KP et al (1996) Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1. Am J Respir Crit Care Med 153:1850-1856
36. Folkesson HG, Matthay MA, Westrom BR et al (1996) Alveolar epithelial clearance of protein. J Appl Physiol 80:1431-1445
37. Meduri GU, Headley S, Kohler G et al (1995) Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time. Chest 107:1062-1073
38. Antonelli M, Bufi M, De Blasi RA et al (1989) Detection of leukotrienes B4, C4 and of their isomers in arterial, mixed venous blood and bronchoalveolar lavage fluid from ARDS patients. Intensive Care Med 15:296-301
39. Stephenson AH, Lonigro AJ, Hyers TM et al (1988) Increased concentrations of leukotrienes in bronchoalveolar lavage fluid of patients with ARDS or at risk for ARDS. Am Rev Respir Dis 138:714-719
40. Taniguchi H, Taki F, Takagi K et al (1986) The role of leukotriene B4 in the genesis of oxygen toxicity in the lung. Am Rev Respir Dis 133:805-808
41. Idell S (2003) Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med 31:S213-S220
42. Prabhakaran P, Ware LB, White KE et al (2003) Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol 285:L20-L28
43. Ware LB, Fang X, Matthay MA (2003) Protein C and thrombomodulin in human acute lung injury. Am J Physiol Lung Cell Mol Physiol 285:L514-L521
44. Muller-Leisse C, Klosterhalfen B, Hauptmann S et al (1993) Computed tomography and histologic results in the early stages of endotoxin-injured pig lungs as a model for adult respiratory distress syndrome. Invest Radiol 28:39-45
45. Harris JA, Hyde DM, Wang QJ et al (1991) Repeated episodes of C5a-induced neutrophil influx do not result in pulmonary fibrosis. Inflammation 15:233-250
46. Ryan AJ, McCoy DM, McGowan SE et al (2003) Alveolar sphingolipids generated in response to TNF-alpha modifies surfactant biophysical activity. J Appl Physiol 94:253-258
47. Suntres ZE, Omri A, Shek PN (2002) Pseudomonas aeruginosa-induced lung injury: role of oxidative stress. Microb Pathog 32:27-34
48. Rocco PRM, Leite-Junior JHP, Souza AB et al (2002) Acute respiratory distress sindrome caused by pulmonary and extrapulmonary disease: effects of corticosteroid. Eur Respir J 20:P343
49. Hoelz C, Negri EM, Lichtenfels AJ et al (2001) Morphometric differences in pulmonary lesions in primary and secondary ARDS. A preliminary study in autopsies. Pathol Res Pract 197:521-530
50. Negri EM, Hoelz C, Barbas CS et al (2002) Acute remodeling of parenchyma in pulmonary and extrapulmonary ARDS. An autopsy study of collagen-elastic system fibers. Pathol Res Pract 198:355-361
51. Chollet-Martin S, Montravers P, Gibert C et al (1993) High levels of interleukin-8 in the blood and alveolar spaces of patients with pneumonia and adult respiratory distress syndrome. Infect Immun 61:4553-4559
52. Bauer TT, Monton C, Torres A et al (2000) Comparison of systemic cytokine levels in patients with acute respiratory distress syndrome, severe pneumonia, and controls. Thorax 55:46-52
53. Schutte H, Lohmeyer J, Rosseau S et al (1996) Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary edema. Eur Respir J 9:1858-1867
54. Barbas CS, Capellozzi VL, Hoelz C (2002) Impact of lung biopsy in acute respiratory distress syndrome. Am J Respir Crit Care Med 165:A218
55. Pesenti A, Pelosi P, Rossi N et al (1991) The effects of positive end-expiratory pressure on respiratory resistance in patients with the adult respiratory distress syndrome and in normal anesthetized subjects. Am Rev Respir Dis 144:101-107
56. D'Angelo E, Calderini E, Robatto FM et al (1997) Lung and chest wall mechanics in patients with acquired immunodeficiency syndrome and severe Pneumocystis carinii pneumonia. Eur Respir J 10:2343-2350
57. Ranieri VM, Brienza N, Santostasi S et al (1997) Impairment of lung and chest wall mechanics in patients with acute respiratory distress syndrome: role of abdominal distension. Am J Respir Crit Care Med 156:1082-1091
58. Puybasset L, Gusman P, Muller JC et al (2000) Regional distribution of gas and tissue in acute respiratory distress syndrome. III. Consequences for the effects of positive end-expiratory pressure. CT Scan ARDS Study Group. Adult Respiratory Distress Syndrome. Intensive Care Med 26:1215-1227
59. Webb HH, Tierney DF (1974) Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure. Am Rev Respir Dis 110:556-565
60. Slutsky AS, Tremblay LN (1998) Multiple system organ failure. Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med 157:1721-1725
61. McHugh LG, Milberg JA, Whitcomb ME et al (1994) Recovery of function in survivors of the acute respiratory distress syndrome. Am J Respir Crit Care Med 150:90-94
62. Herridge MS, Cheung AM, Tansey CM et al (2003) One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 348:683-693
63. Berthiaume Y, Folkesson HG, Matthay MA (2002) Lung edema clearance: 20 years of progress: invited review: alveolar edema fluid clearance in the injured lung. J Appl Physiol 93:2207-2213
64. Martin C, Papazian L, Payan MJ et al (1995) Pulmonary fibrosis correlates with outcome in adult respiratory distress syndrome. A study in mechanically ventilated patients. Chest 107:196-200
65. Farjanel J, Hartmann DJ, Guidet B et al (1993) Four markers of collagen metabolism as possible indicators of disease in the adult respiratory distress syndrome. Am Rev Respir Dis 147:1091-1099
66. Waydhas C, Nast-Kolb D, Trupka A et al (1993) Increased serum concentrations of procollagen type III peptide in severely injured patients: an indicator of fibrosing activity? Crit Care Med 21:240-247
67. Chesnutt AN, Matthay MA, Tibayan FA et al (1997) Early detection of type III procollagen peptide in acute lung injury. Pathogenetic and prognostic significance. Am J Respir Crit Care Med 156:840-845