Characterization of drug-resistant Salmonella enterica serotype typhimurium by antibiograms, plasmids, integrons, resistance genes, and PFGE

Journal of Microbiology and Biotechnology

Volumn 20, Issue 6, 2010, Pages 1042-1052

  Benacer, Douadi ^a   Thong, Kwai Lin ^a   Watanabe, Haruo ^b   Devi Puthucheary, Savithri ^c  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Antimicrobial resistance; Integrons; PFGE; Plasmids; S. typhimurium

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZTREONAM; BACTERIAL PROTEIN; BETA LACTAMASE TEM 1; CEFALEXIN; CEFALOTIN; CEFEPIME; CEFOTAXIME; CEFRADINE; CEFTAZIDIME; CEFTIOFUR; CEFTRIAXONE; CEFUROXIME; CHLORAMPHENICOL; CIPROFLOXACIN; CLAVULANIC ACID; COTRIMOXAZOLE; GENTAMICIN; KANAMYCIN; NALIDIXIC ACID; PROTEIN AADA; PROTEIN STRA; PROTEIN SUL1; STREPTOMYCIN; SULFONAMIDE; TETRACYCLINE; TRIMETHOPRIM; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL STRAIN; CONTROLLED STUDY; GENETIC VARIABILITY; INTEGRON; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PULSED FIELD GEL ELECTROPHORESIS; SALMONELLA TYPHIMURIUM; ANIMAL; ANIMAL SALMONELLOSIS; BOVINAE; CHICKEN; CLASSIFICATION; DRUG EFFECTS; GENETICS; HUMAN; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOLECULAR GENETICS; PHYLOGENY; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLOSIS; SWINE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CATTLE; CHICKENS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; HUMANS; INTEGRONS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PLASMIDS; SALMONELLA INFECTIONS; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; SWINE;

SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA TYPHIMURIUM;

EID: 77954974202     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.0910.10028     Document Type: Article

References (34)

1. Aarestrup, F. M., C. Wiuff, K. Molbak, and E. J. Threlfall. 2003. Is it time to change fluoroquinolone breakpoints for Salmonella spp.? Antimicrob. Agents Chemother. 47: 827-829.
2. Aarestrup, F. M., M. Lertworapreecha, M. C. Evans, A. Bangtrakulnonth, T. Chalermchaikit, R. S. Hendriksen, and H. C. Wegener. 2003. Antimicrobial susceptibility and occurrence of resistance genes among Salmonella enterica serovar Weltevreden from different countries. J. Antimicrob. Chemother. 52: 715-718.
3. Adaska, J. M., A. J. Silva, A. C. Berge, and W. M. Sischo. 2006. Genetic and phenotypic variability among Salmonella enterica serovar Typhimurium isolates from California dairy cattle and humans. Appl. Environ. Microbiol. 72: 6632-6637.
4. Alvarez, J., M. Sota, A. B. Vivanco, I. Perales, R. Cisterna, A. Rementeria, and J. Garaizar. 2004. Development of a multiplex PCR technique for detection and epidemiological typing of Salmonella in human clinical samples. J. Clin. Microbiol. 42: 1734-1738.
5. Antunes, P., J. Machado, J. C. Sousa, and L. Peixe. 2005. Dissemination of sulfonamide resistance genes (sul1, sul2, and sul3) in Portuguese Salmonella enterica strains and relation with integrons. Antimicrob. Agents Chemother. 49: 836-839.
6. Antunes, P., J. Machado, and L. Peixe. 2006. Characterization of antimicrobial resistance and class 1 and 2 integrons in Salmonella enterica isolates from different sources in Portugal. J. Antimicrob. Chemother. 58: 297-304.
7. Biendo, M., G. Laurans, D. Thomas, B. Canarelli, F. Hamdad-Daoudi, F. Rousseau, S. Castelain, and F. Eb. 2005. Molecular characterisation and mechanisms of resistance of multidrug-resistant human Salmonella enterica serovar Typhimurium isolated in Amiens (France). Int. J. Antimicrob. Agents 26: 219-229.
8. Boyd, D. A., G. A. Peters, L.-K. Ng, and M. R. Mulvey. 2000. Partial characterization of a genomic island associated with the multidrug resistance region of Salmonella enterica Typhimurium DT104. FEMS Microbiol. Lett. 189: 285-291.
9. Cardoso, M. O., A. R. Ribeiro, L. R. dos Santos, F. Pilotto, H. L. S. de Moraes, C. T. P. Salle, S. L. S. Rocha, and V. P. do Nascimento. 2006. Antibiotic resistance in Salmonella Enteritidis isolated from broiler carcasses. Braz. J. Microbiol. 37: 368-371.
10. Chen, S., S. Zhao, D. G. White, C. M. Schroeder, R. Lu, H. Yang, P. F. McDermott, S. Ayers, and J. Meng. 2004. Characterization of multiple-antimicrobial-resistant Salmonella serovars isolated from retail meats. Appl. Environ. Microbiol. 70: 1-7.
11. Clinical and Laboratory Standards Institute. 2005. Performance Standards for Antimicrobial Susceptibility Testing Approved Standard. M100-S15. Clinical and Laboratory Standards Institute, Wayne, PA.
12. Daly, M., J. Buckley, E. Power, C. O'Hare, M. Cormican, B. Cryan, P. G Wall, and S. Fanning. 2000. Molecular characterization of Irish Salmonella enterica serotype Typhimurium: Detection of class I integrons and assessment of genetic relationships by DNA amplification fingerprinting. Appl. Environ. Microbiol. 66: 614-619.
13. Foley, S. L., D. G. White, P. F. McDermott, R. D. Walker, B. Rhodes, P. J. Fedorka-Cray, S. Simjee, and S. Zhao. 2006. Comparison of subtyping methods for differentiating Salmonella enterica serovar typhimurium isolates obtained from food animal sources. J. Clin. Microbiol. 44: 3569-3577.
14. Guerra, B., S. Soto, S. Cal, and M. C. Mendoza. 2000. Antimicrobial resistance and spread of class 1 integrons among Salmonella serotypes. Antimicrob. Agents Chemother. 44: 2166-2169.
15. Guerra, B., S. M. Soto, J. M. Arguelles, and M. C. Mendoza. 2001. Multidrug resistance is mediated by large plasmids carrying a class 1 integron in the emergent Salmonella enterica serotype [4,5,12:i:-]. Antimicrob. Agents Chemother. 45: 1305-1308.
16. Hansen, J. B. and R. H. Olsen. 1978. Isolation of large bacterial plasmids and characterization of the P2 incompatibility group plasmids pMG1 and pMG5. J. Bacteriol. 135: 227-238.
17. Heurtin-Le Corre, C., P. Y. Donnio, M. Perrin, M. F. Travert, and J. L. Avril. 1999. Increasing incidence and comparison of nalidixic acid-resistant Salmonella enterica subsp. enterica serotype Typhimurium isolates from humans and animals. J. Clin. Microbiol. 37: 266-269.
18. Lailler, R., F. Grimont, Y. Jones, P. Sanders, and A. Brisabois. 2002. Subtyping of Salmonella Typhimurium by pulsed-field gel electrophoresis and comparisons with phage types and resistance types. Pathol. Biol. 50: 361-368.
19. Lauderdale, T. L., F. M. Aarestrup, P. C. Chen, J. F. Lai, H. Y. Wang, Y. R. Shiau, I. W. Huang, C. L. Hung, and TSAR hospitals. 2006. Multidrug resistance among different serotypes of clinical Salmonella isolates in Taiwan. Diagn. Microbiol. Infect. Dis. 55: 149-155.
20. Lévesque, C., L. Pyché, C. Larose, and P. H. Roy. 1995. PCR mapping of integrons reveals several novel combinations of resistance genes. Antimicrob. Agents Chemother. 39: 185-191.
21. Liebana, E., L. Garcia-Migura, C. Clouting, F. A. Clifton-Hadley, E. Lindsay, E. J. Threlfall, S. W. McDowell, and R. H. Davies. 2002. Multiple genetic typing of Salmonella enterica serotype Typhimurium isolates of different phage types (DT104, U302, DT204b, and DT49) from animals and humans in England, Wales, and Northern Ireland. J. Clin. Microbiol. 40: 4450-4456.
22. Ng, L. K., M. R. Mulvey, I. Martin, G. A. Peters, and W. Johnson. 1999. Genetic characterization of antimicrobial resistance in Canadian isolates of Salmonella serovar Typhimurium DT104. Antimicrob. Agents Chemother. 43: 3018-3021.
23. Oliver, A., L. M. Weigel, J. K. Rasheed, J. E. McGowan, P. Raney, and F. C. Tenover. 2002. Mechanisms of decreased susceptibility to cefpodoxime in Escherichia coli. Antimicrob. Agents Chemother. 46: 3829-3836.
24. Olsen, J. E., D. J. Brown, D. L. Baggesen, and M. Bisgaard. 1994. Stability of plasmids in five strains of Salmonella maintained in stab culture at different temperatures. J. Appl. Bacteriol. 77: 155-159.
25. Randall, L. P., S. W. Cooles, M. K. Osborn, L. J. Piddock, and M. J. Woodward. 2004. Antibiotic resistance genes, integrons and multiple antibiotic resistance in thirty-five serotypes of Salmonella enterica isolated from humans and animals in the U.K. J. Antimicrob. Chemother. 53: 208-216.
26. Tassios, P. T., M. Gazouli, E. Tzelepi, H. Milch, N. Kozlova, S. Sidorenko, N. J. Legakis, and L. S. Tzouvelekis. 1999. Spread of a Salmonella typhimurium clone resistant to expanded-spectrum cephalosporins in three European countries. J. Clin. Microbiol. 37: 3774-3777.
27. Taylor, D. N., I. K. Wachsmuth, Y. H. Shangkuan, E. V. Schmidt, T. J. Barrett, J. S. Shchrader, et al. 1982. Salmonellosis associated with marijuana: A multistate outbreak traced by plasmid fingerprinting. N. Engl. J. Med. 306: 1249-1253.
28. Thong, K. L., K. S. Lai, and Y. L. Goh. 2003. Technical improvement in DNA preparation in pulsed field electrophoresis. Malaysian J. Sci. 22: 55-59.
29. Threlfall, E. J. 2000. Multiresistant Salmonella Typhimurium DT 104: A truly international multiresistant clone. J. Antimicrob. Chemother. 46: 7-10.
30. Threlfall, E. J. 2002. Antimicrobial drug resistance in Salmonella: Problems and perspectives in food- and water-borne infections. FEMS Microbiol. Rev. 26: 141-148.
31. Wain, J., L. T. Diem Nga, C. Kidgell, K. James, S. Fortune, T. Song Diep, et al. 2003. Molecular analysis of incHI1 antimicrobial resistance plasmids from Salmonella serovar Typhi strains associated with typhoid fever. Antimicrob. Agents Chemother. 47: 2732-2739.
32. Woo, Y. K. and S. H. Lee. 2006. Genetic diversity of multi-resistant Salmonella enterica serotype Typhimurium isolates from animals and humans. J. Microbiol. 44: 106-112.
33. Yang, S. J., K.Y. Park, S. H. Kim, K. M. No, T. E. Besser, H. S. Yoo, S. H. Kim, B. K. Lee, and Y. H. Park. 2002. Antimicrobial resistance in Salmonella enterica serovars Enteritidis and Typhimurium isolated from animals in Korea: Comparison of phenotypic and genotypic resistance characterization. Vet. Microbiol. 86: 295-301.
34. Yasin, R. M., M. M. Jegathesan, and C. C. Tiew. 1997. Salmonella serotypes isolated in Malaysia over the ten-year period 1983-1992. Asia Pac. J. Public Health 9: 1-5.