Noradrenaline induces clock gene Per1 mRNA expression in C6 glioma cells through β2-adrenergic receptor coupled with protein kinase A - cAMP response element binding protein (PKA-CREB) and Src-tyrosine kinase - glycogen synthase kinase-3β (Src-GSK-3β)

Journal of Pharmacological Sciences

Volumn 113, Issue 3, 2010, Pages 234-245

  Morioka, Norimitsu ^a   Sugimoto, Tatsuhiko ^a   Tokuhara, Masato ^a   Dohi, Toshihiro ^b   Nakata, Yoshihiro ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Astrocyte; Glycogen synthase kinase 3 ; Noradrenaline; Per1; Tyrosine kinase

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN INHIBITOR; GENISTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; KN 501; LITHIUM CHLORIDE; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NORADRENALIN; PER1 PROTEIN; PROTEIN INHIBITOR; PROTEIN TYROSINE KINASE; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION REGULATION; GLIOMA CELL; NONHUMAN; NORADRENERGIC SYSTEM; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION;

EID: 77954968253     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10031FP     Document Type: Article

References (41)

1. Dunlap J. Circadian rhythms: an end in the beginning. Science. 1998;280:1548-1549.
2. Sassone-Corsi P. Molecular clocks: mastering time by gene regulation. Nature. 1998;392:871-874.
3. King DP, Takahashi JS. Molecular genetics of circadian rhythms in mammals. Annu Rev Neurosci. 2000;23:713-742.
4. Spanagel R, Pendyala G, Abarca C, Zghoul T, Sanchis-Segura C, Magnne MC, et al. The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nature Med. 2005;11:35-42.
5. Cai W, Rambaud J, Teboul M, Masse I, Benoit G, Gustafsson JA, et al. Expression levels of estrogen receptor β are modulated by components of the molecular clock. Mol Cell Biol. 2008; 28:784-793.
6. Shinohara K, Honma S, Katsuno Y, Abe H, Honma K. Two distinct oscillators in the rat suprachiasmatic nucleus in vitro. Proc Natl Acad Sci U S A. 1995;92:7396-7400.
7. Guldner FH. Numbers of neurons and astroglial cells in the suprachiasmatic nucleus of male and female rats. Exp Brain Res. 1983;50:373-376.
8. Prosser RA, Edgar DM, Heller HC, Miller JD. A possible glial role in the mammalian circadian clock. Brain Res. 1994;643: 296-301.
9. Prolo LM, Takahashi JS, Herzog ED. Circadian rhythm generation and entrainment in astrocytes. J Neurosci. 2005;25:404-408.
10. Akiyama M, Kouzu Y, Takahashi S, Wakamatsu H, Moriya T, Maetani M, et al. Inhibition of light- or glutamate-induced mPer1 expression represses the phase shifts into the mouse circadian locomotor and suprachiasmatic firing rhythms. J Neurosci. 1999; 19:1115-1121.
11. Hannibal J, Jamen F, Nielsen HS, Journot L, Brabet P, Fahrenkrug J. Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor. J Neurosci. 2001;21:4883-4890.
12. Varcoe TJ, Kennaway DJ. Activation of 5HT2C receptors acutely induces Per1 gene expression in the rat SCN in vitro. Brain Res. 2008;1209:19-28.
13. Cagampang FRA, Okamura H, Inouye ST. Circadian rhythms of norepinephrine in the rat suprachiasmatic nucleus. Neurosci Lett. 1994;173:185-188.
14. Semba J, Toru M, Mataga N. Twenty-four hour rhythms of norepinephrine and serotonin in nucleus suprachiasmaticus, raphe nuclei, and locus coeruleus in the rat. Sleep. 1984;7:211-218.
15. Vacher CM, Frétier P, Créminon C, Seif I, De Maeyer E, Calas A, et al. Monoaminergic control of vasopressin and VIP expression in the mouse suprachiasmatic nucleus. J Neurosci Res. 2003; 71:791-801.
16. Terazono H, Mutoh T, Yamaguchi S, Kobayashi M, Akiyama M, Udo R, et al. Adrenergic regulation of clock gene expression in mouse liver. Proc Natl Acad Sci U S A. 2003;100:6795-6800.
17. Takata M, Burioka N, Ohdo S, Fukuoka Y, Miyata M, Endo M, et al. β 2-adrennoceptor agonists induce the mammalian clock gene, h Per1, mRNA in cultured human bronchial epithelium cells in vitro. Chronobiol Int. 2005;22:777-783.
18. Hertz L, Chen Y, Gibbs ME, Zang P, Peng L. Astrocytic adrenoceptors: a major drug target in neurological and psychiatric disorders? Curr Drug Targets CNS Neurol Disord. 2004;3:239-267.
19. Morioka N, Abdin JM, Morita K, Kitayama T, Nakata Y, Dohi T. The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase C α in C6 glioma cells. Neurochem Int. 2008; 53:248-254.
20. Fujioka A, Takashima N, Shigeyoshi Y. Circadian rhythm generation in a glioma cell line. Biochem Biophys Res Commun. 2006; 346:169-174.
21. Morioka N, Tanabe H, Inoue A, Dohi T, Nakata Y. Noradrenaline reduces the ATP-stimulated phosphorylation of p38 MAP kinase via β adrenergic receptors-cAMP-protein kinase A-dependent mechanism in cultured rat spinal microglia. Neurochem Int. 2009;55:226-234.
22. Yagita K, Okamura H. Forskolin induces circadian gene expression of rPer1, rPer2 and dbp in mammalian rat-1 fibroblasts. FEBS Lett. 2000;465:79-82.
23. Best JL, Amezcua CA, Mayr B, Flechner L, Murawsky CM, Emerson B, et al. Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. Proc Natl Acad Sci U S A. 2004;101:17622-17627.
24. Lesort M, Jope RS, Johnson GVW. Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3β and Fyn tyrosine kinase. J Neurochem. 1999;72:576-584.
25. Iitaka C, Miyazaki K, Akaike T, Ishida N. A role for glycogen synthase-3β in the mammalian circadian clock. J Biol Chem. 2005;280:29397-29402.
26. Bhat RV, Shanley J, Correll MP, Fieles WE, Keith RA, Scott CW, et al. Regulation and localization of tyrosine 216 phosphorylation of glycogen synthase kinase-3β in cellular and animal models of neuronal degeneration. Proc Natl Acad Sci U S A. 2000;97: 11074-11079.
27. Yeh WL, Lu DY, Lee J, Fu WM. Leptin induces migration and invasion of glioma cells through MMP-13 production. Glia. 2009;57:454-464.
28. Gumz ML, Stow LR, Lynch IJ, Greenlee MM, Rudin A, Cain BD, et al. The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice. J Clin Invest. 2009;119:2433-2434.
29. Akiyama M, Minami Y, Kuriyama K, Shibata S. MAP kinasedependent induction of clock gene expression by α 1 -adrenergic receptor activation. FEBS Lett. 2003;542:109-114.
30. 2 -adrenergic receptor to different G proteins by protein kinase A. Nature. 1997;390:88-91.
31. 2 -adrenergic receptor signaling pathways. J Allergy Clin Immunol. 2002;110:S229-S235.
32. Akiyama M, Minami Y, Nakajima T, Moriya T, Shibata S. Calcium and pituitary adenylate cyclase-activating polypeptide induce expression of circadian clock gene mPer1 in the mouse cerebellar granule cell culture. J Neurochem. 2001;78:499-508.
33. Hinoi E, Ueshima T, Hojo H, Iemata M, Takarada T, Yoneda Y. Upregulation of per mRNA expression by parathyroid hormone through a protein kinase A-CREB-dependent mechanism in chondrocytes. J Biol Chem. 2006;281:23632-23642.
34. He Q, Wu G, Lapointe MC. Isoproterenol and cAMP regulation of the human brain natriuretic peptide gene involves Src and Rac. Am J Physiol Endocrinol Metab. 2000;278:E1115-E1123.
35. Kronfeld I, Kazimirsky G, Lorenzo PS, Garfield SH, Blumberg PM, Brodie C. Phosphorylation of protein kinase C δ on distinct tyrosine residues regulates specific cellular functions. J Biol Chem. 2000;275:35491-35498.
36. Tsuchioka M, Takebayashi M, Hisaoka K, Maeda N, Nakata Y. Serotonin (5HT) induces glial cell line-derived neurotrophic factor (GDNF) mRNA expression via the transactivation of fibroblast growth factor receptor 2 (FGFR2) in rat C6 glioma cells. J Neurochem. 2008;106:244-257.
37. Takahashi-Yanaga F, Shiraishi F, Hirata M, Miwa Y, Morimoto S, Sasaguri T. Glycogen synthase kinase-3β is tyrosine-phosphorylated by MEK1 in human skin fibroblasts. Biochem Biophys Res Commun. 2000;316:411-415.
38. Menon B, Johnson JN, Ross RS, Singh M, Singh K. Glycogen synthase kinase-3β plays a pro-apoptotic role in β -adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes: role of β 1 integrins. J Mol Cell Cardiol. 2007;42:653-661.
39. Moriya T, Yoshinobu Y, Kouzu Y, Katoh A, Gomi H, Ikeda M, et al. Involvement of glial fibrillary acidic protein (GFAP) expressed in astroglial cells in circadian rhythm under constant lighting conditions in mice. J Neurosci Res. 2000;60:212-218.
40. Lindley J, Deurveilher S, Rusak B, Semba K. Transforming growth factor- β and glial fibrillary acidic protein in the hamster circadian system: daily profile and cellular localization. Brain Res. 2008;1197:94-105.
41. Hsiao HY, Mak OT, Yang CS, Liu YP, Fang KM, Tzeng SF. TNF-α /IFN-γ -induced iNOS expression increased by prostaglandin E 2 in rat primary astrocytes via EP2-evoked cAMP/PKA and intracellular calcium signaling. Glia. 2007;55:214-223.