The ultrastructural study of tumorigenic cells using nanobiomarkers

Cancer Biotherapy and Radiopharmaceuticals

Volumn 25, Issue 3, 2010, Pages 289-298

  Pavon, Lorena Favaro ^a   Marti, Luciana Cavalheiro ^a   Sibov, Tatiana Tais ^a   Malheiros, Suzana M F ^b   Oliveira, Daniela Mara ^c   Guilhen, Daiane Donna ^a   Camargo Mathias, Maria Izabel ^d   Junior, Edson Amaro ^a,e   Gamarra, Lionel Fernel ^a  

^a HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO JOÃO DEL REI   (Brazil)

^d SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

cancer diagnosis; glioblastoma; immunolocalization; markers; nanoparticles; ultrastructural

Indexed keywords

MONOCLONAL ANTIBODY; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

ARTICLE; ASTROCYTOMA; CANCER CELL CULTURE; CANCER SURVIVAL; CARCINOGENESIS; CELL LABELING; CONTROLLED STUDY; FLOW CYTOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; TUMOR RECURRENCE; ULTRASTRUCTURE;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD29; ANTIGENS, CD44; BIOLOGICAL MARKERS; CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEUS; CYTOPLASM; CYTOPLASMIC VESICLES; ENDOCYTOSIS; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GLIOBLASTOMA; GLYCOPROTEINS; HUMANS; IMMUNOPHENOTYPING; MAGNETITE NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; NANOMEDICINE; NANOPARTICLES; PEPTIDES; QUANTUM DOTS; RECEPTORS, CELL SURFACE; STAINING AND LABELING; TUMOR CELLS, CULTURED;

EID: 77954932502     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2009.0697     Document Type: Article

References (35)

1. Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008;359:492.
2. Sordi V, Malosio ML, Marchesi F, et al. Bone marrow mes- enchymal stem cell express a restricted set of sunctionally active chemokine receptors capacle of promoting migration to pancreatic islets. Blood 2005;106:419.
3. Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004;432:396.
4. Jaiswal JK, Mattoussi H, Mauro JM, Simon SM. Long-term multiple color imaging of live cells using quantum dot bio- conjugates. Nat Biotechnol 2003;21:47.
5. Kumar CSSR. Nanomaterials for Cancer Diagnosis. Wein- heim: WILEY-VCH, 2007.
6. Tartaj P, del Puerto M, Morales S, et al. Preparation, structural and magnetic characterization of synthetic anti ferromagnetic (SAF) nanoparticles. Phys D Appl Phys 2003;36:R182.
7. Voltairas PA, Fotiadis DI, Michalis LKJ. Hydrodynamics of magnetic drug targeting. J Biomechanics 2002;35:813.
8. Jordan A, Wust P, Scholz R, et al. Cellular uptake of magnetic fluid particles and their effects in AC magnetic fields on human adenocarcinoma cells in vitro. Int J Hyperth 1997;13:587.
9. Jordan A, Scholz R, Wust P, et al. Endocytosis of dextran and silan-coated magnetite nanoparticles and the effect of intracellular hyperthermia on human mammary carcinoma cells in vitro. J Magn Magn Mater 1999;194:185.
10. Weissleder R, Elizondo G, Wittenberg J, et al. Ultrasmall superparamagnetic iron oxide: Characterization of a new class of contrast agents for MR imaging. Radiology 1990;175:489.
11. Kim DK, Zhang Y, Kehr J, et al. Characterization and MRI study of surfactant-coated superparamagnetic nanoparticles administered into the rat brain. J Magn Magn Mater 2001; 225:256.
12. Cheng FY, Su CH, Yang YS, et al. Characterization of aqueous dispersions of Fe3O4 nanoparticles and their biomedical applications. Biomaterials 2005;26:729.
13. Kumar CSSR. Nanosystem Characterization Tools in the Life Sciences. Weinheim: WILEY-VCH, 2007.
14. Alivisatos AP. Semiconductor clusters, nanocrystals and quantum dots. Science 1996;271:933.
15. Lee JH, Huh YM, Jun YW, et al. Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging. Nat Med 2007;13:95.
16. Nisman R, Dellaire G, Ren Y, et al. Application of quantum dots as probes for correlative fluorescence, conventional, and energy-filtered transmission electron microscopy. J Histochem Cytochem 2004;52:13.
17. Zimmer JP, Kim SW, Ohnishi S, et al. Size series of small indium arsenide-zinc selenide core-shell nanocrystals and their application to in vivo imaging. J Am Chem Soc 2006;128:2526.
18. Wu X, Liu H, Liu J, et al. Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nat Biotechnol 2003;21:41.
19. Gao X, Cui Y, Levenson RM, et al. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Bio- technol 2004;22:969.
20. Ballou B, Ernst LA, Andreko S, et al. Sentinel lymph node imaging using quantum dots in mouse tumor models. Bio- conjug Chem 2007;18:389.
21. Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114:97.
22. Simberg D, Duza T, Park JH, et al. Biomimetic amplification of nanoparticle homing to tumors. Proc Natl Acad Sci U S A 2007;104:932.
23. Tso C, Shintaku P, Chen J, et al. Primary glioblastomas express mesenchymal stem-like properties. Mol Cancer Res 2006;4:607.
24. Rudzki Z, Johthy S. CD44 and the adhesion of neoplastic cells. Mol Pathol 1997;50:57.
25. Shinkai M, Yanase M, Honda H, et al. Intracellular hy- perthermia for cancer using magnetic cationic liposomes. Jpn J Cancer Res 1996;87:1179.
26. Margaritescu C, Simionescu C, Mogoanta L, et al. Endoglin (CD105) and microvessel density in oral squamous cell carcinoma. Rom J Morphol Embryol 2008;49:321.
27. Voura EB, Jaiswal JK, Mattoussi H, Simon SM. Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat Med 2004;10:993.
28. Reddy GR, Bhojani MS, McConville P, et al. Vascular targeted nanoparticles for imaging and treatment of brain tumors. Clin Cancer Res 2006;12:6677.
29. Liu M, Dai B, Kang SH, et al. Fox M1B is overexpressed in human glioblstomas and critically regulates the tumorige- nicity of glioma cells. Cancer Res 2006;66:3593.
30. Jackson H, Muhammad O, Daneshvar H, et al. Quantum dots are phagocytized by macrophages and colocalize with experimental gliomas. Neurosurgery 2007;60:524.
31. Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003; 63:5821.
32. Beier D, Hau P, Proescholdt M, et al. CD133+ and CD133- glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 2007;67:4010.
33. Zeppernick F, Ahmadi R, Campos B, et al. Stem cell marker CD133 affects clinical outcome in gliomas patients. Clin Cancer Res 2008;14:123.
34. Daldrup-Link HE, Rudelius M, Oostendorp RA, et al. Targeting of hematopoietic progenitor cells with MR contrast agents. Radiology 2003;228:760.
35. Hartig W, Paulke BR, Varga C, et al. Electron microscopic analysis of nanoparticles, delivering thioflavin-T after intra- hippocampal injection in mouse: Implications for targeting b-amyloid in Alzheimer's disease. Neurosci Lett 2003;338:174.