A novel fluid resuscitation strategy modulates pulmonary transcription factor activation in a murine model of hemorrhagic shock

Clinics

Volumn 65, Issue 6, 2010, Pages 621-628

  Costantini, Todd W ^a   Deree, Jessica ^a   Martins, J O ^a   Putnam, James G ^a   de Campos, Tercio ^a   Coimbra, Raul ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CREB; CREB binding protein; Hypertonic saline; NF kB; Pentoxifylline

Indexed keywords

ANTIINFLAMMATORY AGENT; AUTACOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR PROTEIN; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITOR; SODIUM CHLORIDE; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; DISEASE MODEL; HEMORRHAGIC SHOCK; LUNG; MALE; METABOLISM; METHODOLOGY; PATHOLOGY; RAT; REPERFUSION INJURY; RESUSCITATION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; LUNG; MALE; NF-KAPPA B; NUCLEAR PROTEINS; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RESUSCITATION; SALINE SOLUTION, HYPERTONIC; SHOCK, HEMORRHAGIC; TRANSCRIPTION FACTORS;

EID: 77954911026     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1807-59322010000600010     Document Type: Article

References (39)

1. Aldridge AJ. Role of the Neutrophil in Septic Shock and the adult respiratory distress syndrome. Eur J Surg. 2002;168:204-14.
2. Bazzoni F, Cassatella MA, Laudanna C, Rossi F. Phagocytosis of opsonized yeast induces tumor necrosis factor-α mRNA accumulation and protein release by human polymorphonuclear leukocytes. J Leukoc Biol. 1991;50:223-8.
3. Strieter RM, Kasahara K, Allen RM, Standiford TJ, Rolfe MW, Becker FS, et al. Cytokine-induced neutrophil-derived interleukin-8. Am J Path. 1992;141:397-407.
4. Sha WC. Regulation of immune responses by NF-κB/Rel transcription factors. J Exp Med. 1998;187:143-6.
5. Nakamori Y, Koh T, Ogura H, Tanaka H, Fujimi S, Kasai K, et al. Enhanced expression of intranuclear NF-κB in primed polymorphonuclear leukocytes in systemic inflammatory response syndrome patients. J Trauma. 2003;54:253-60.
6. Arnalich F, Garcia-Palomero E, Lopez J, Jimenez M, Madero R, Renart J, et al. Predictive value of nuclear factor κB activity and plasma cytokine levels in patients with sepsis. Infect Immun. 2000;68:1942-5.
7. Siebenlist U, Franzoso G, and Brown K. Structure, regulation, and function of NF-κB. Annu Rev Cell Biol. 1994;10:405-55.
8. Baldwin AS. The NF-κB and I-κB proteins; new discoveries and insights. Annu Rev Immunol. 1996;14:649-81.
9. Tran K, Merika M, Thanos D. Distinct functional properties of IkappaB alpha and IkappaB beta. Mol Cell Biol 1997;17:5386-99.
10. Shaywitz AJ, Greenberg ME. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem. 1999;68:821-61.
11. Shenkar R, Yum K, Arcaroli J, Kupfner J, Abraham E. Interactions between CBP, NF-κB, and CREB in the lungs after hemorrhage and endotoxemia. Am J Physiol Lung Cell Mol Physiol. 2001;281:L418-L26.
12. Savage SA, Fitzpatrick CM, Kashyap VS, Clouse WD, Kerby JD. Endothelial dysfunction after lactated ringer's solution resuscitation for hemorrhagic shock. J Trauma. 2005;59:284-90.
13. Koustova E, Stanton K, GushchinV, Alam HB, Stegalkina S, Rhee PM. Effects of lactated ringer's solutions on human leukocytes. J Trauma. 2002;52:872-8.
14. Alam HB, Stanton K, Koustova E, Burris D, Rich N, Rhee PM. Effect of different resuscitation strategies on neutrophil activation in a swine model of hemorrhagic shock. Resuscitation. 2004;60:91-9.
15. Yada-Langui MM, Coimbra R, Lancellotti C, Mimica I, Garcia C, Correia N Jr, et al. Hypertonic saline and pentoxifylline prevent lung injury and bacterial translocation after hemorrhagic shock. Shock. 2000;14:594-8.
16. Rizoli SB, Kapus A, Fan J, Li YH, Marshall JC, Rotstein OD. Immunomodulatory effects of hypertonic resuscitation on the development of lung inflammation following hemorrhagic shock. J Immunol. 1998;161:6288-96.
17. Coimbra R, Melbostad H, Loomis W, Porcides R, Wolf P, Tobar M, et al. LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on pro-inflammatory mediators, metalloproteinases, NF-κB, and ICAM-1 expression. J Trauma. 2006;60:115-25.
18. Rizoli SB, Rhind SG, Shek PN, Inaba K, Filips D, Tien H, et al. The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock. Ann Surg. 2006;243:47-57.
19. Deree J, Martins JO, Leedom A, Lamon A, Putnam J, et al. Hypertonic Saline and Pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis. J Trauma. 2007;62:104-11.
20. Coimbra R, Porcides R, Loomis W, Melbostad H, Lall R, Deree J, et al. HSPTX protects against hemorrhagic shock resuscitation-induced tissue injury: an attractive alternative to ringer's lactate. J Trauma. 2006;60:41-51.
21. Gerritsen ME, Williams AJ, Neish AS, Moore S, Shi Y, Collins T. CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci. 1997;94:2927-32.
22. Lee WL and Downey GP. Neutrophil activation and acute lung injury. Curr Opin Crit Care. 2001;7:1-7.
23. Porter JM, Cutler BS, Lee BY, Reich T, Reichle FA, Scogin JT, et al. Pentoxifylline efficacy in the treatment of intermittent claudication: Multicenter double-blind trial with objective assessment of chronic occlusive arterial disease patients. Am Heart J. 1982;104:66-72.
24. Coimbra R, Melbostad H, Hoyt DB. Effects of phosphodiesterase inhibition on the inflammatory response following shock: role of pentoxifylline. J Trauma. 2004;56:442-9.
25. Waxman K. Shock: ischemia, reperfusion, and inflammation. New Horiz. 1996;4:153-60.
26. Flynn WJ, Cryer HG, Garrison RN. Pentoxifylline restores intestinal microvascular blood flow during resuscitated hemorrhagic shock. Surgery. 1991;110:350-6.
27. Barroso-Aranda J and Schmid-Schonbein GW. Pentoxifylline pretreatment decreases the pool of circulating activated neutrophils, in-vivo adhesion to endothelium, and improves survival from hemorrhagic shock. Biorheology. 1990;27:401-18.
28. Mukaida N, Okamoto S, Ishikawa Y, Matsushima K. Molecular mechanism of interleukin-8 gene expression. J Leuk Biol. 1994;56:554-8.
29. Yoshida S, Ono M, Shono T, Izumo H, Ishibashi T, Suzuki H, et al. Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis. Mol Cell Biol. 1997;17:4015-23.
30. Renard P, Percherancier Y, Kroll M, Thomas D, Virelizier J, Arenzana-Seisdedos F, et al. Inducible NF-κB activation is permitted by simultaneous degradation of nuclear IκBα. J Biol Chem. 2000;275:15193-9.
31. Lancaster LH, Christman JW, Blackwell TR, Koay MA, Blackwell TS. Suppression of lung inflammation in rats by prevention of NF-κB activation in the liver. Inflammation. 2001;25:25-31.
32. Coimbra R, Melbostad H, Loomis W, Tobar M, Hoyt DB. Phosphodiesterase inhibition decreases nuclear factor-κB activation and shifts the cytokine response toward anti-inflammatory activity in acute endotoxemia. J Trauma. 2005;59:575-82.
33. Ollivier V, Parry GC, Cobb RR, de Prost D, Mackman N. Elevated cyclic AMP inhibits NK-κB-mediated transcription in human monocytic cells and endothelial cells. J Biol Chem. 1996;271:20828-35.
34. Minguet S, Huber M, Rosenkranz L, Schamel WA, Reth M, Brummer T. Adenosine and cAMP are potent inhibitors of the NF-κB pathway downstream on immunoreceptors. Eur J Immunol. 2005;35:31-41.
35. Haddad JJ, Land SC, Tarnow-Mordi WO, Zembala M, Kowalczyk D, Lauterbach R. Immunopharmacological potential of selective phosphodiesterase inhibition. II. Evidence for the involvement of an inhibitory-κB/nuclear factor-κB-sensitive pathway in alveolar epithelial cells. J Pharmacol Exp Ther. 2002;300:567-76.
36. Zhong H, May MJ, Jimi E, Ghosh S. The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell. 2002;9:625-36.
37. Naumann M and Scheidereit C. Activation of NF-κB in vivo is regulated by multiple phosphorylations. EMBO J. 1994;13:4597-607.
38. Coimbra R, Loomis W, Melbostad H, Tobar M, Porcides RD, Lall R, Holbrook et al. Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-α synthesis: a novel resuscitation strategy. J Trauma. 2005;59:257-65.
39. Shenkar R and Abraham E. Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-κB, and cyclic AMP response element binding protein. J Immunol. 1999;163:954-62.