Sexual function after stereotactic body radiotherapy for prostate cancer: Results of a prospective clinical trial

International Journal of Radiation Oncology Biology Physics

Volumn 78, Issue 2, 2010, Pages 442-448

  Wiegner, Ellen A ^a   King, Christopher R ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Erectile dysfunction; Prostate cancer; Quality of life; Stereotactic radiotherapy

Indexed keywords

AFTER-TREATMENT; ANDROGEN DEPRIVATION THERAPY; CLINICAL TRIAL; CYBERKNIFE; ERECTILE DYSFUNCTION; EXPANDED PROSTATE CANCER INDEX COMPOSITES; LITERATURE REVIEWS; PENILE BULB; PHASE II; PROSTATE CANCERS; QUALITY OF LIFE; STEREOTACTIC BODY RADIOTHERAPY; STEREOTACTIC RADIOTHERAPY;

DISEASES; EXPERIMENTS;

RADIOTHERAPY;

SILDENAFIL; TADALAFIL; VARDENAFIL; CYCLIC GMP PHOSPHODIESTERASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; ERECTILE DYSFUNCTION; HUMAN; MALE; PRIORITY JOURNAL; PROSTATE CANCER; QUALITY OF LIFE; QUESTIONNAIRE; RADIATION DOSE; SCORING SYSTEM; SEXUAL FUNCTION; STEREOTACTIC BODY RADIATION THERAPY; AGE; DISEASE COURSE; MIDDLE AGED; PENIS; PENIS ERECTION; PHASE 2 CLINICAL TRIAL; PHYSIOLOGY; PROSPECTIVE STUDY; PROSTATIC NEOPLASMS; RADIATION DOSE FRACTIONATION; RADIATION RESPONSE; RADIOSURGERY; TREATMENT OUTCOME; VERY ELDERLY;

3',5'-CYCLIC-GMP PHOSPHODIESTERASES; AGE FACTORS; AGED; AGED, 80 AND OVER; DISEASE PROGRESSION; DOSE FRACTIONATION; ERECTILE DYSFUNCTION; HUMANS; MALE; MIDDLE AGED; PENILE ERECTION; PENIS; PROSPECTIVE STUDIES; PROSTATIC NEOPLASMS; QUALITY OF LIFE; QUESTIONNAIRES; RADIOSURGERY; TREATMENT OUTCOME;

EID: 77954893757     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.07.1748     Document Type: Article

References (38)

1. H.A. Feldman, I. Goldstein, and D.G. Hatzichristou Impotence and its medical and psychosocial correlates: Results of the Massachusetts male aging study J Urol 151 1994 54 61
2. J. Crook, B. Esche, and N. Futter Effect of pelvic radiotherapy for prostate cancer on bowel, bladder, and sexual function: The patient's perspective Urology 47 1996 387 394
3. A.L. Potosky, J. Legler, and P.C. Albertsen Health outcomes after prostatectomy or radiotherapy for prostate cancer: Results from the prostate cancer outcomes study J Natl Cancer Inst 92 2000 1582 1592
4. G.J. van der Wielen, W. van Putten, and L. Incrocci Sexual function after three-dimensional conformal radiotherapy for prostate cancer: Results from a dose-escalation trial Int J Radiat Oncol Biol Phys 68 2007 479 484
5. A.J. Lim, A.H. Brandon, and J. Fiedler Quality of life: Radical prostatectomy versus radiation therapy for prostate cancer J Urol 154 1995 1420 1425
6. R. Raina, A. Agarwal, and K.K. Goyal Long-term potency after Iodine-125 radiotherapy for prostate cancer and role of sildenafil citrate Urology 62 2003 1103 1108
7. G.M. Duchesne, S.G. Williams, and R. Das Patterns of toxicity following high-dose-rate brachytherapy boost for prostate cancer: Mature prospective Phase I/II study results Radiother Oncol 84 2007 128 134
8. F. Joly, D. Brune, and J.E. Couette Health-related quality of life and sequelae in patients treated with brachytherapy and external beam irradiation for localized prostate cancer Ann Oncol 9 1998 751 757
9. F.L. Greene, D.L. Page, and I.D. Flemming AJCC Manual for staging cancer 6th ed. 2002 Springer Verlag New York p. 309-13
10. C.R. King, J.D. Brooks, and H. Gill Stereotactic body radiotherapy for localized prostate cancer: Interim results of a prospective Phase II clinical trial Int J Radiat Oncol Biol Phys 73 2009 1043 1048
11. J.T. Wei, R.L. Dunn, and M.S. Litwin Development and validation of the expanded prostate cancer index composite (EPIC) for comprehensive assessment of health-related quality of life in men with prostate cancer Urology 56 2000 899 905
12. M.G. Sanda, R.L. Dunn, and J. Michalski Quality of life and satisfaction among prostate cancer survivors N Engl J Med 358 2008 1250 1261
13. M.J. Barry Quality of life and prostate cancer treatment J Urol 162 1999 407
14. G.R. Norman, J.A. Sloan, and K.W. Wyrwich Interpretation of changes in health-related quality of life; the remarkable universality of half a standard deviation Med Care 41 2003 582 592
15. J.T. Wei, R.L. Dunn, and H.M. Sandler Comprehensive comparison of health-related quality of life after contemporary therapies for localized prostate cancer J Clin Oncol 20 2002 557 566
16. D.C. Miller, M.G. Sanda, and R.L. Dunn Long-term outcomes among localized prostate cancer survivors: Health-related quality-of life changes after radical prostatectomy, external radiation, and brachytherapy J Clin Oncol 23 2005 2772 2780
17. A.S. Hamilton, J.L. Stanford, and F.D. Gilliland Health outcomes after external-beam radiation therapy for clinically localized prostate cancer: Results from the prostate cancer outcomes study J Clin Oncol 19 2001 2517 2526
18. C.J. Beard, K.J. Propert, and P.P. Rieker Complications after treatment with external-beam irradiation in early-stage prostate cancer patients: A prospective multiinstitutional outcomes study J Clin Oncol 15 1997 223 229
19. A.R. Helgason, M. Fredrikson, and J. Adolfsson Decreased sexual capacity after external radiation therapy for prostate cancer impairs quality of life Int J Radiat Oncol Biol Phys 32 1995 33 39
20. C.T. Chen, R.K. Valicenti, and J. Lu Does hormonal therapy influence sexual function in men receiving 3D conformal radiation therapy for prostate cancer? Int J Radiat Oncol Biol Phys 50 2001 591 595
21. D.F. Penson, Z. Feng, and A. Kuniyuki General quality of life 2 years following treatment for prostate cancer: What influences outcomes? Results from the prostate cancer outcomes study J Clin Oncol 21 2003 1147 1154
22. M. Pinkawa, B. Gagel, and M.D. Piroth Erectile dysfunction after external beam radiotherapy for prostate cancer Eur Urol 55 2009 227 236
23. S.D. Fossa, H. Waehre, and K.H. Kurth Influence of urological morbidity on quality of life in patients with prostate cancer Eur Urol Suppl 31 1997 3 8
24. L.N. Nguyen, A. Pollack, and G.K. Zagars Late effects after radiotherapy for prostate cancer in a randomized dose-response study: Results of a self-assessment questionnaire Urology 51 1998 991 997
25. D.J. Little, D.A. Kuban, and L.B. Levy Quality-of-life questionnaire results 2 and 3 years after radiotherapy for prostate cancer in a randomized dose-escalation study Urology 62 2003 707 713
26. S.J. Feigenberg, W.R. Lee, and M.L. Desilvio Health-related quality of life in men receiving prostate brachytherapy on RTOG 98-05 Int J Radiat Oncol Biol Phys 62 2005 956 964
27. D.C. Miller, J.T. Wei, and R.L. Dunn Use of medications or devices for erectile dysfunction among long-term prostate cancer treatment survivors: Potential influence of sexual motivation and/or indifference Urology 68 2006 166 171
28. G.J. van der Wielen, M.S. Hoogeman, and G.R. Dohle Dose-volume parameters of the corpora cavernosa do not correlate with erectile dysfunction after external beam radiotherapy for prostate cancer: results from a dose-escalation trial Int J Radiat Oncol Biol Phys 71 2008 795 800
29. A.N. Solan, J.A. Cesaretti, N.N. Stone, and R.G. Stock There is no correlation between erectile dysfunction and dose to penile bulb and neurovascular bundles following real-time low-dose-rate prostate brachytherapy Int J Radiat Oncol Biol Phys 73 2009 1468 1474
30. M.W. Brown, J.P. Brooks, P.S. Albert, and M.M. Poggi An analysis of erectile function after intensity modulated radiation therapy for localized prostate carcinoma Prostate Cancer Prostatic Dis 10 2007 189 193
31. A.G. Macdonald, M. Keyes, and A. Kruk Predictive factors for erectile dysfunction in men with prostate cancer after brachytherapy: Is dose to the penile bulb important? Int J Radiat Oncol Biol Phys 63 2005 155 163
32. U. Selek, R. Cheung, and M. Lii Erectile dysfunction and radiation dose to penile base structures: A lack of correlation Int J Radiat Oncol Biol Phys 59 2004 1039 1046
33. B.M. Fisch, B. Pickett, V. Weinberg, and M. Roach Dose of radiation received by the bulb of the penis correlates with risk of impotence after three-dimensional conformal radiotherapy for prostate cancer Urology 57 2001 955 959
34. S.A. Mangar, M.R. Sydes, and H.L. Tucker Evaluating the relationship between erectile dysfunction and dose received by the penile bulb: Using data from a randomised controlled trial of conformal radiotherapy in prostate cancer (MRC RT01) Radiother Oncol 80 2006 355 362
35. A.G. Wernicke, R. Valicenti, and K. Dieva Radiation dose delivered to the proximal penis as a predictor of the risk of erectile dysfunction after three-dimensional conformal radiotherapy for localized prostate cancer Int J Radiat Oncol Biol Phys 60 2004 1357 1363
36. G.S. Merrick, W.M. Butler, and K.E. Wallner The importance of radiation doses to the penile bulb vs. crura in the development of postbrachytherapy erectile dysfunction Int J Radiat Oncol Biol Phys 54 2002 1055 1062
37. M. Roach, K. Winter, and J.M. Michalski Penile bulb dose and impotence after three-dimensional conformal radiotherapy for prostate cancer on RTOG 9406: Findings from a prospective, multi-institutional, Phase I/II dose-escalation study Int J Radiat Oncol Biol Phys 60 2004 1351 1356
38. G.J. van der Wielen, J.P. Mulhall, and L. Incrocci Erectile dysfunction after radiotherapy for prostate cancer and radiation dose to the penile structures: a critical review Radiother Oncol 84 2007 107 113