Chemical, antifungal and cytotoxic evaluation of the essential oil of Thymus zygis subsp. sylvestris

Industrial Crops and Products

Volumn 32, Issue 1, 2010, Pages 70-75

  Goncalves M J ^a   Cruz, M T ^b   Cavaleiro, C ^a   Lopes, M C ^b   Salgueiro, L ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Antifungal activity; Essential oils; In vitro cytotoxicity; Thymus zygis subsp. sylvestris

Indexed keywords

ANTI-FUNGAL; ANTI-MICROBIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ASPERGILLUS STRAINS; BIOLOGICALLY ACTIVE COMPOUNDS; CELL VIABILITY; CHEMOTYPES; CYTOTOXIC; CYTOTOXIC EFFECTS; DENDRITIC CELLS; DETRIMENTAL EFFECTS; GC AND GC; HIGH-CONTENT; IN VITRO CYTOTOXICITY; IN-VITRO; LAMIACEAE; MAMMALIAN CELLS; MTT ASSAYS; PHARMACEUTICAL INDUSTRY; THERAPEUTIC PROPERTIES;

CYTOTOXICITY; DENDRIMERS; DRUG PRODUCTS PLANTS; FUNGI; MAMMALS; PHENOLS;

ESSENTIAL OILS;

ANTIMICROBIAL ACTIVITY; CHEMICAL COMPOUND; DOSE-RESPONSE RELATIONSHIP; ENDEMIC SPECIES; ESSENTIAL OIL; HERB; PHARMACEUTICAL INDUSTRY; PHENOL; TOXICITY TEST;

ASPERGILLUS; LAMIACEAE; MAGNOLIOPHYTA; MAMMALIA; THYMUS (THYME); THYMUS ZYGIS;

ANTIFUNGAL PROPERTY; OIL; TOXICITY;

EID: 77954864678     PISSN: 09266690     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.indcrop.2010.03.005     Document Type: Article

References (34)

1. Adams R.P. Identification of Essential Oil Components by Gas Chromatography/Mass Spectroscopy 2004, Allured Publishing Corporation, Carol Stream, Illinois, USA.
2. Bakkali F., Averbeck S., Averbeck D., Idaomar M. Biological effects of essential oils-a review. Food Chem. Toxicol. 2008, 46:446-475.
3. Burdock G.A., Carabin I.G. Safety assessment of coriander (Coriandrum sativum L.) essential oil as a food ingredient. Food Chem. Toxicol. 2009, 47:22-34.
4. Bimczok D., Rau H., Sewekow E., Janczyk P., Souffrant W.B., Rothkötter H.J. Influence of carvacrol on proliferation and survival of porcine lymphocytes and intestinal epithelial cells in vitro. Toxicol. In Vitro 2008, 22:652-658.
5. Council of Europe European Pharmacopoeia 1997, Strasbourg, pp. 121-122. 3rd ed.
6. Dijoux N., Guingand Y., Bourgeois C., Durand S., Fromageot C., Combe C., Ferret P.J. Assessment of the phototoxic hazard of some essential oils using modified 3T3 neutral red uptake assay. Toxicol. In Vitro 2006, 20:480-489.
7. Fabian D., Sabol M., Domaracká K., Bujnáková D. Essential oils-their antimicrobial activity against Escherichia coli and effect on intestinal cell viability. Toxicol. In Vitro 2006, 20:1435-1445.
8. Figueiredo A.C., Barroso J.G., Pedro L.G., Salgueiro L., Miguel M.G., Faleiro M.L. Portuguese Thymbra and Thymus species volatiles: chemical composition and biological activities. Curr. Pharm. Des. 2008, 1:3120-3140.
9. Girolomoni G., Lutz M.B., Pastore S., Abmann C.U., Cavani A., Ricciardi-Castagnoli P. Establishment of a cell line with features of early dendritic cell precursors from fetal mouse skin. Eur. J. Immunol. 1995, 25:2163-2169.
10. Hayes A.J., Markovic B. Toxicity of Australian essential oil Backhousia citriodora (Lemon myrtle). Part 1. Antimicrobial activity and in vitro cytotoxicity. Food Chem. Toxicol. 2002, 40:535-543.
11. Horváthová E., Sramková M., Lábaj J., Slamenová D. Study of cytotoxic, genotoxic and DNA-protective effects of selected plant essential oils on human cells cultured in vitro. Neuroendocrinol. Lett. 2006, 27(Suppl. 2):44-47.
12. Joulain D., Konig W.A. The Atlas of Spectral Data of Sesquiterpene Hydrocarbon 1998, B. Verlag Hamburg, Hamburg, pp. 1-657.
13. Kaloustian J., Chevalier J., Mikail C., Martino M., Abou L., Vergnes M.F. Study of six essential oils: chemical composition and antibacterial activity. Phytotherapie 2008, 6(3):160-164.
14. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
15. NCCLSa-National Committee for Clinical Laboratory Standards, 2002. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts. Approved Standard M27-A2. Wayne, PA, USA.
16. NCCLSb-National Committee for Clinical Laboratory Standards, 2002. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi. Approved Standard M38-A. Wayne, PA, USA.
17. Pérez-Sánchez R., Infante F., Gálvez C., Ubera J.L. Fungitoxic activity against phytopathogenic fungi and the chemical composition of Thymus zygis essential oils. Food Sci. Technol. Int. 2007, 13:341-347.
18. Pina-Vaz C., Gonçalves R.A., Pinto E., Costa-de-Oliveira S., Tavares C., Salgueiro L., Cavaleiro C., Gonçalves M.J., Martinez-de-Oliveira J. Antifungal activity of Thymus oils and their major compounds. J. Eur. Acad. Dermatol. Venereol. 2004, 18:73-78.
19. Pinto E., Pina-Vaz C., Salgueiro L., Gonçalves M.J., Costa-de-Oliveira S., Cavaleiro C., Palmeira A., Rodrigues A., Martinez-de-Oliveira J. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J. Med. Microbiol. 2006, 55:1367-1373.
20. Prashar A., Locke I.C., Evans C.S. Cytotoxicity of lavender oil and its major components to human skin cells. Cell Prolif. 2004, 37:221-229.
21. Roselli M., Britti M.S., Le Huërou-Luron I., Marfaing H., Zhu W.Y., Mengheri E. Effect of different plant extracts and natural substances (PENS) against membrane damage induced by enterotoxigenic Escherichia coli K88 in pig intestinal cells. Toxicol. In Vitro 2007, 21:224-229.
22. Sáez F. Essential oil variability of Thymus zygis growing wild in southeastern Spain. Phytochemistry 1995, 40:819-825.
23. Sáez F., Stahl-Biskup E. Essential oil polymorphism in the genus Thymus. Medicinal and Aromatic Plants-Industrial Profiles 2002, vol. 17:125-143. Taylor & Francis.
24. Salgueiro L.R., Proença da Cunha A. Composição do óleo essencial de Thymus zygis subsp. sylvestris (Hoffmanns. & Link) Brot. Ex Coutinho da região de centro de Portugal. Bol. Fac. Farm. Coimbra 1987, 11:107-118.
25. Salgueiro L.R., Vila R., Tomàs X., Tomi F., Cañigueral S., Casanova J., Proença da Cunha A., Adzet T. Chemical polymorphism of the essential oil of Thymus carnosus from Portugal. Phytochemistry 1995, 38:391-396.
26. Salgueiro L.R., Vila R., Tomàs X., Cañigueral S., Proença da Cunha A., Adzet T. Composition and variability of essential oils of Thymus species from section Mastichina from Portugal. Biochem. Syst. Ecol. 1997, 25:659-672.
27. Salgueiro L.R., Vila R., Tomàs X., Tomi F., Cañigueral S., Paiva J., Proença da Cunha A., Adzet T. Chemotaxonomic study on Thymus villosus from Portugal. Biochem. Syst. Ecol. 2000, 28:471-482.
28. Salgueiro L., Cavaleiro C., Pinto E., Pina-Vaz C., Rodrigues A.G., Palmeira A., Tavares C., Gonçalves M.J., Martinez-de-Oliveira J. Chemical composition and antifungal activity of the essential oil of Thymbra capitata. Plant. Med. 2004, 70:569-571.
29. Salgueiro L., Pinto E., Gonçalves M., Pina-Vaz C., Cavaleiro C., Palmeira A., Martinez-de-Oliveira J. Antifungal activity and chemical composition of the essential oil of Thymus capitellatus. Flav. Frag. J. 2006, 21:749-753.
30. Slamenová D., Horváthová E., Sramková M., Marsálková L. DNA-protective effects of two components of essential plant oils carvacrol and thymol on mammalian cells cultured in vitro. Neoplasma 2007, 54:108-112.
31. Stahl-Biskup E. Essential oil chemistry of the genus Thymus-a global view. Medicinal and Aromatic Plants-Industrial Profiles 2002, vol. 17:75-124. Taylor & Francis.
32. Stammati A., Bonsi P., Zucco F., Moezelaar R., Alakomi H.L., von Wright A. Toxicity of selected plant volatiles in microbial and mammalian short-term assays. Food Chem. Toxicol. 1999, 37:813-823.
33. Wilson C.L., Solar J.M., El Ghaouth A., Wisniewski M.E. Rapid evaluation of plant extracts and essential oils for antifungal activity against Botrytis cinerea. Plant Dis. 1997, 81(2):204-210.
34. Zarzuelo A., Crespo E. The medicinal and non-medicinal uses of thyme. Medicinal and Aromatic Plants-Industrial Profiles 2002, vol. 17:263-292. Taylor & Francis.