Clathrin assembly lymphoid myeloid leukemia-AF10-positive acute leukemias: A report of 2 cases with a review of the literature

Korean Journal of Laboratory Medicine

Volumn 30, Issue 2, 2010, Pages 117-121

  Huh, Ji Young ^a   Chung, Soie ^b   Oh, Doyeun ^a   Kang, Myung Seo ^a   Eom, Hyeon Seok ^c   Cho, Eun Hae ^d   Han, Mi Hwa ^c   Kong, Sun Young ^c  

^a CHA University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c National Cancer Center   (South Korea)

^d Green Cross Reference Laboratory   (South Korea)

Author keywords

Acute leukemia; CALM AF10; HDOT1L; HOXA gene; Reverse transcriptase PCR; T(10; 11)

Indexed keywords

CLATHRIN ASSEMBLY PROTEIN; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; HOMEODOMAIN PROTEIN; MLLT10 PROTEIN, HUMAN; ONCOPROTEIN; PICALM PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; BONE MARROW; CASE REPORT; CHROMOSOME 10; CHROMOSOME 11; CORD BLOOD STEM CELL TRANSPLANTATION; FEMALE; GENE TRANSLOCATION; GENETICS; HUMAN; MALE; METABOLISM; PATHOLOGY; RECURRENT DISEASE;

ADOLESCENT; ADULT; BONE MARROW; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 11; CORD BLOOD STEM CELL TRANSPLANTATION; FEMALE; HISTONE-LYSINE N-METHYLTRANSFERASE; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MONOMERIC CLATHRIN ASSEMBLY PROTEINS; ONCOGENE PROTEINS, FUSION; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC;

EID: 77954860000     PISSN: 15986535     EISSN: None     Source Type: Journal    
DOI: 10.3343/kjlm.2010.30.2.117     Document Type: Article

References (14)

1. Bohlander SK, Muschinsky V, Schrader K, Siebert R, Schlegelberger B, Harder L, et al. Molecular analysis of the CALM/AF10 fusion: identical rearrangements in acute myeloid leukemia, acute lymphoblastic leukemia and malignant lymphoma patients. Leukemia 2000; 14:93-9.
2. Jones LK, Chaplin T, Shankar A, Neat M, Patel N, Samuel DP, et al. Identification and molecular characterisation of a CALM-AF10 fusion in acute megakaryoblastic leukaemia. Leukemia 2001;15:910-4.
3. Nakamura F, Maki K, Arai Y, Nakamura Y, Mitani K. Monocytic leukemia with CALM/AF10 rearrangement showing mediastinal emphysema. Am J Hematol 2003;72:138-42.
4. Caudell D and Aplan PD. The role of CALM-AF10 gene fusion in acute leukemia. Leukemia 2008;22:678-85.
5. Carlson KM, Vignon C, Bohlander S, Martinez-Climent JA, Le Beau MM, Rowley JD. Identification and molecular characterization of CALM/AF10fusion products in T cell acute lymphoblastic leukemia and acute myeloid leukemia. Leukemia 2000;14:100-4.
6. Kumon K, Kobayashi H, Maseki N, Sakashita A, Sakurai M, Tanizawa A, et al. Mixed-lineage leukemia with t(10;11)(p13;q21): an analysis of AF10-CALM and CALM-AF10 fusion mRNAs and clinical features. Genes Chromosomes Cancer 1999;25:33-9.
7. Asnafi V, Radford-Weiss I, Dastugue N, Bayle C, Leboeuf D, Charrin C, et al. CALM-AF10 is a common fusion transcript in T-ALL and is specific to the TCRgammadelta lineage. Blood 2003;102:1000-6.
8. Dik WA, Brahim W, Braun C, Asnafi V, Dastugue N, Bernard OA, et al. CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes. Leukemia 2005;19: 1948-57.
9. Okada Y, Jiang Q, Lemieux M, Jeannotte L, Su L, Zhang Y. Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L. Nat Cell Biol 2006;8:1017-24.
10. Kim KH and Han JY. Simultaneous reverse transcription-polymerase chain reaction for detection of 7 gene rearrangements in acute leukemia. Korean J Clin Pathol 2001;21:24-33.
11. Sundstrom C and Nilsson K. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer 1976; 17:565-77.
12. Sitwala KV, Dandekar MN, Hess JL. HOX proteins and leukemia. Int J Clin Exp Pathol 2008;1:461-74.
13. Okada Y, Feng Q, Lin Y, Jiang Q, Li Y, Coffield VM, et al. hDOT1L links histone methylation to leukemogenesis. Cell 2005;121:167-78.
14. Van Vlierberghe P, van Grotel M, Tchinda J, Lee C, Beverloo HB, van der Spek PJ, et al. The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia. Blood 2008;111:4668-80.