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Volumn 56, Issue 2, 2010, Pages 59-70
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Overloading ion-exchange membranes as a purification step for monoclonal antibodies
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Author keywords
Competitive adsorption; Displacement chromatography; Flow through chromatography; Ion exchange membrane; Monoclonal antibody (mAB); Overload chromatography
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Indexed keywords
ADSORBERS;
ANION EXCHANGE MEMBRANE;
CHINESE HAMSTER OVARY;
COMPETITIVE ADSORPTION;
DISPLACEMENT CHROMATOGRAPHY;
FEED STREAMS;
FLOWTHROUGH;
FRONTAL CHROMATOGRAPHY;
HOST CELL PROTEIN;
IMPURITY ADSORPTION;
ION-EXCHANGE COLUMNS;
LIGAND INTERACTIONS;
MEMBRANE LOADING;
MEMBRANE PROPERTIES;
MONOCLONAL ANTIBODIES (MAB);
NORMAL FLOW;
PREFERENTIAL BINDING;
PROTEIN A;
REMOVAL OF IMPURITIES;
ADSORPTION;
ALLERGIES;
COLUMN CHROMATOGRAPHY;
IMPURITIES;
ION CHROMATOGRAPHY;
ION EXCHANGE;
IONS;
LOADING;
MERGERS AND ACQUISITIONS;
MONOCLONAL ANTIBODIES;
PROTEINS;
PURIFICATION;
SURFACE PLASMON RESONANCE;
ION EXCHANGE MEMBRANES;
CELL PROTEIN;
GENTAMICIN;
MONOCLONAL ANTIBODY;
PROTEIN A;
ADSORPTION;
ANIMAL CELL;
ANION EXCHANGE;
ANTIBODY ISOLATION;
ANTIGEN BINDING;
ARTICLE;
ARTIFICIAL MEMBRANE;
CATION EXCHANGE;
CHO CELL;
CHROMATOGRAPHY;
CONDUCTANCE;
DRUG BINDING;
ENZYME LINKED IMMUNOSORBENT ASSAY;
FLOW RATE;
GEL PERMEATION CHROMATOGRAPHY;
HOST CELL;
ION EXCHANGE;
ION EXCHANGE CHROMATOGRAPHY;
MEMBRANE BINDING;
MEMBRANE TRANSPORT;
NONHUMAN;
PH;
PROTEIN PURIFICATION;
ANIMALS;
ANTIBODIES, MONOCLONAL;
CHO CELLS;
CHROMATOGRAPHY, ION EXCHANGE;
CRICETINAE;
CRICETULUS;
DRUG CONTAMINATION;
ELECTRIC CONDUCTIVITY;
GENTAMICINS;
HYDROGEN-ION CONCENTRATION;
ION EXCHANGE RESINS;
MEMBRANES, ARTIFICIAL;
STAPHYLOCOCCAL PROTEIN A;
CRICETINAE;
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EID: 77954829098
PISSN: 08854513
EISSN: None
Source Type: Journal
DOI: 10.1042/BA20090369 Document Type: Article |
Times cited : (29)
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References (23)
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