A novel steroidal inhibitor of estrogen-related receptor α (ERRα)

Biochemical Pharmacology

Volumn 80, Issue 6, 2010, Pages 819-826

  Duellman, Sarah J ^a   Calaoagan, Joy M ^a   Sato, Barbara G ^a   Fine, Richard ^b   Klebansky, Boris ^b   Chao, Wan Ru ^a   Hobbs, Peter ^a   Collins, Nathan ^a   Sambucetti, Lidia ^a   Laderoute, Keith R ^a  

^a SRI INTERNATIONAL   (United States)

^b BioComputing Group Inc   (United States)

Author keywords

Antitumor agent; Estrogen related receptor ; Metabolism; Steroid

Indexed keywords

21 [2 (N,N DIMETHYLAMINO)ETHYL]OXY 7A METHYL 19 NORPREGNA 1,3,5(10),17(20) TETRAEN 3 OL; ANTIESTROGEN; ANTINEOPLASTIC AGENT; ESTROGEN RELATED RECEPTOR ALPHA; ESTROGEN RELATED RECEPTOR BETA; ESTROGEN RELATED RECEPTOR GAMMA; PACLITAXEL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SR 16388; STEROID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EXPOSURE; DRUG SELECTIVITY; ENHANCER REGION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; RECEPTOR BINDING; REPORTER GENE; TRANSCRIPTION INITIATION; TUMOR CELL LINE; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; ESTRADIOL; ESTROGEN ANTAGONISTS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; RECEPTORS, ESTROGEN; STEROIDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77954819506     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.05.024     Document Type: Article

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