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Volumn 87, Issue 3, 2010, Pages 569-577

Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension

Author keywords

Arginase; Arteries; Endothelial function; Remodelling; Spontaneously hypertensive rat

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN II; ARGINASE; ARGINASE 1; COLLAGEN; ENZYME INHIBITOR; N OMEGA HYDROXYNORARGININE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG; ARGININE; CARDIOVASCULAR AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; MEMBRANE PROTEIN; N(OMEGA)-HYDROXYNORARGININE; PTGS1 PROTEIN, RAT; PTGS2 PROTEIN, RAT; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

EID: 77954812507     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq081     Document Type: Article
Times cited : (96)

References (44)
  • 3
    • 0035957368 scopus 로고    scopus 로고
    • Role of arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation
    • Ignarro LJ, Buga G, Wie LH, Bauer PM, Wu G, del Soldato P. Role of arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation. Proc Natl Acad Sci USA 2001;98:4202-4208.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4202-4208
    • Ignarro, L.J.1    Buga, G.2    Wie, L.H.3    Bauer, P.M.4    Wu, G.5    Del Soldato, P.6
  • 4
    • 0035347173 scopus 로고    scopus 로고
    • Constitutive expression of arginase in microvascular endothelial cells counteracts nitric-oxide-mediated vaso-dilatory function
    • Zhang C, Hein TW, Wang W, Miller MW, Chang CI, Kuo L. Constitutive expression of arginase in microvascular endothelial cells counteracts nitric-oxide-mediated vaso-dilatory function. FASEB J 2001;15:1264-1266.
    • (2001) FASEB J , vol.15 , pp. 1264-1266
    • Zhang, C.1    Hein, T.W.2    Wang, W.3    Miller, M.W.4    Chang, C.I.5    Kuo, L.6
  • 5
    • 18344378606 scopus 로고    scopus 로고
    • Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats
    • Demougeot C, Prigent-Tessier A, Marie C, Berthelot A. Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats. J Hypertens 2005;25:971-978.
    • (2005) J Hypertens , vol.25 , pp. 971-978
    • Demougeot, C.1    Prigent-Tessier, A.2    Marie, C.3    Berthelot, A.4
  • 6
    • 42549088600 scopus 로고    scopus 로고
    • Endothelial arginase II: A novel target for the treatment of atherosclerosis
    • Ryoo S, Gupta G, Benjo A, Lim HK, Camara A, Sikka G et al. Endothelial arginase II: a novel target for the treatment of atherosclerosis. Circ Res 2008;102:923-932.
    • (2008) Circ Res , vol.102 , pp. 923-932
    • Ryoo, S.1    Gupta, G.2    Benjo, A.3    Lim, H.K.4    Camara, A.5    Sikka, G.6
  • 7
  • 8
    • 38849146382 scopus 로고    scopus 로고
    • Significance of nitric oxide and its modulation mechanisms by endogenous nitric oxide synthase inhibitors and arginase in the micturition disorders and erectile dysfunction
    • Masuda H. Significance of nitric oxide and its modulation mechanisms by endogenous nitric oxide synthase inhibitors and arginase in the micturition disorders and erectile dysfunction. Int J Urol 2008;15:128-134.
    • (2008) Int J Urol , vol.15 , pp. 128-134
    • Masuda, H.1
  • 9
    • 0142023863 scopus 로고    scopus 로고
    • Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels
    • Berkowitz DE, White R, Li D, Minhas KM, Cernetich A, Kim S et al. Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels. Circulation 2003;108:2000-2006.
    • (2003) Circulation , vol.108 , pp. 2000-2006
    • Berkowitz, D.E.1    White, R.2    Li, D.3    Minhas, K.M.4    Cernetich, A.5    Kim, S.6
  • 10
    • 0028626329 scopus 로고
    • The endothelium in hypertension: Bystander target or mediator?
    • Lüscher TF. The endothelium in hypertension: bystander, target or mediator? J Hypertens 1994;12:S106-S116.
    • (1994) J Hypertens , vol.12
    • Lüscher, T.F.1
  • 11
    • 0033975122 scopus 로고    scopus 로고
    • Increased arginase activity in aorta of mineralocorticoid-salt hypertensive rats
    • Rodriguez S, Richert L, Berthelot A. Increased arginase activity in aorta of mineralocorticoid-salt hypertensive rats. Clin Exp Hypertens 2000;22:75-85.
    • (2000) Clin Exp Hypertens , vol.22 , pp. 75-85
    • Rodriguez, S.1    Richert, L.2    Berthelot, A.3
  • 13
    • 9644282852 scopus 로고    scopus 로고
    • Upre-gulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles
    • Zhang C, Hein TW, Wang W, Miller MW, Fossum TW, McDonald MM et al. Upre-gulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles. Hypertension 2004;44:1-9.
    • (2004) Hypertension , vol.44 , pp. 1-9
    • Zhang, C.1    Hein, T.W.2    Wang, W.3    Miller, M.W.4    Fossum, T.W.5    McDonald, M.M.6
  • 14
    • 33846922529 scopus 로고    scopus 로고
    • Time course of vascular arginase expression and activity in spontaneously hypertensive rats
    • Demougeot C, Prigent-Tessier A, Bagnost T, André C, Guillaume Y, Bouhaddi M et al. Time course of vascular arginase expression and activity in spontaneously hypertensive rats. Life Sci 2007;80:1128-1134.
    • (2007) Life Sci , vol.80 , pp. 1128-1134
    • Demougeot, C.1    Prigent-Tessier, A.2    Bagnost, T.3    André, C.4    Guillaume, Y.5    Bouhaddi, M.6
  • 15
    • 34249733810 scopus 로고    scopus 로고
    • Up-regulation of arginase activity contributes to attenuated reflex cutaneous vasodilatation in hypertensive humans
    • Holowatz LA, Kenney WL. Up-regulation of arginase activity contributes to attenuated reflex cutaneous vasodilatation in hypertensive humans. J Physiol 2007;581: 863-872.
    • (2007) J Physiol , vol.581 , pp. 863-872
    • Holowatz, L.A.1    Kenney, W.L.2
  • 16
    • 43449084960 scopus 로고    scopus 로고
    • Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat
    • Bagnost T, Berthelot A, Bouhaddi M, Laurant P, André C, Guillaume Y et al. Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat. J Hypertens 2008;26:1110-1118.
    • (2008) J Hypertens , vol.26 , pp. 1110-1118
    • Bagnost, T.1    Berthelot, A.2    Bouhaddi, M.3    Laurant, P.4    André, C.5    Guillaume, Y.6
  • 17
    • 23844543149 scopus 로고    scopus 로고
    • Antihypertensive treatment: Should it be titrated to blood pressure reduction or to target organ damage regression?
    • Redon J. Antihypertensive treatment: should it be titrated to blood pressure reduction or to target organ damage regression? Curr Opin Nephrol Hypertens 2005; 14:448-452.
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 448-452
    • Redon, J.1
  • 18
  • 20
    • 0034745189 scopus 로고    scopus 로고
    • Short-term bio-mechanical adaptation of the rat carotid to acute hypertension: Contribution of smooth muscle
    • Fridez P, Makino A, Miyazaki H, Meister JJ, Hayashi K, Stergiopulos N. Short-term bio-mechanical adaptation of the rat carotid to acute hypertension: contribution of smooth muscle. Ann Biomed Eng 2001;29:26-34.
    • (2001) Ann Biomed Eng , vol.29 , pp. 26-34
    • Fridez, P.1    Makino, A.2    Miyazaki, H.3    Meister, J.J.4    Hayashi, K.5    Stergiopulos, N.6
  • 21
    • 34548102417 scopus 로고    scopus 로고
    • Dexa-methasone decreases contraction to electrical field stimulation in mesenteric arteries from spontaneously hypertensive rats through decreases in thromboxane A2 release
    • Aras-Lopéz R, Blanco-Rivero J, Xavier FE, Salaices M, Ferrer M, Balfagón G. Dexa-methasone decreases contraction to electrical field stimulation in mesenteric arteries from spontaneously hypertensive rats through decreases in thromboxane A2 release. J Pharmacol Exp Ther 2007;322:1129-1136.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 1129-1136
    • Aras-Lopéz, R.1    Blanco-Rivero, J.2    Xavier, F.E.3    Salaices, M.4    Ferrer, M.5    Balfagón, G.6
  • 22
    • 33947431513 scopus 로고    scopus 로고
    • Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats
    • Alvarez Y, Pérez-Girón JV, Hernanz R, Briones AM, Garć?a-Redondo A, Beltrán A et al. Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats. J Pharmacol Exp Ther 2007;321:381-388.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 381-388
    • Alvarez, Y.1    Pérez-Girón, J.V.2    Hernanz, R.3    Briones, A.M.4    Garća-Redondo, A.5    Beltrán, A.6
  • 23
    • 0036096507 scopus 로고    scopus 로고
    • Endothelial function in mesenteric resistance arteries from the genetically hypertensive rat
    • Liu H, Ledingham JM, Mullaney I, Laverty R. Endothelial function in mesenteric resistance arteries from the genetically hypertensive rat. Clin Exp Pharmacol Physiol 2002;29: 405-411.
    • (2002) Clin Exp Pharmacol Physiol , vol.29 , pp. 405-411
    • Liu, H.1    Ledingham, J.M.2    Mullaney, I.3    Laverty, R.4
  • 24
    • 0032995232 scopus 로고    scopus 로고
    • Altered angiotensin II-induced small artery contraction during the development of hypertension in spontaneously hypertensive rats
    • Endemann D, Touyz RM, Li JS, Deng LY, Schiffrin EL. Altered angiotensin II-induced small artery contraction during the development of hypertension in spontaneously hypertensive rats. Am J Hypertens 1999;12:716-723.
    • (1999) Am J Hypertens , vol.12 , pp. 716-723
    • Endemann, D.1    Touyz, R.M.2    Li, J.S.3    Deng, L.Y.4    Schiffrin, E.L.5
  • 25
    • 17144428089 scopus 로고    scopus 로고
    • Acute and chronic effects of free radicals on alpha1-adrenergic-induced vasoconstriction in mesenteric beds of spontaneously hypertensive rats
    • Girouard H, de Champlain J. Acute and chronic effects of free radicals on alpha1-adrenergic-induced vasoconstriction in mesenteric beds of spontaneously hypertensive rats. J Hypertens 2005;23:807-814.
    • (2005) J Hypertens , vol.23 , pp. 807-814
    • Girouard, H.1    De Champlain, J.2
  • 26
    • 0032974823 scopus 로고    scopus 로고
    • Functional characterization of endothelin receptors in hypertensive resistance vessels
    • Montagnani M, Potenza MA, Rinaldi R, Mansi G, Nacci C, Serio M et al. Functional characterization of endothelin receptors in hypertensive resistance vessels. J Hypertens 1999;17:45-52.
    • (1999) J Hypertens , vol.17 , pp. 45-52
    • Montagnani, M.1    Potenza, M.A.2    Rinaldi, R.3    Mansi, G.4    Nacci, C.5    Serio, M.6
  • 27
    • 34447528959 scopus 로고    scopus 로고
    • Arginase: A critical regulator of nitric oxide synthesis and vascular function
    • Durante W, Johnson FK, Johnson RA. Arginase: a critical regulator of nitric oxide synthesis and vascular function. Clin Exp Pharmacol Physiol 2007;34:906-911.
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 906-911
    • Durante, W.1    Johnson, F.K.2    Johnson, R.A.3
  • 28
    • 22944434894 scopus 로고    scopus 로고
    • Modulation of prostaglan-din biosynthesis by nitric oxide and nitric oxide donors
    • Mollace V, Muscoli C, Masini E, Cuzzocrea S, Salvemini D. Modulation of prostaglan-din biosynthesis by nitric oxide and nitric oxide donors. Pharmacol Rev 2005;57: 217-252.
    • (2005) Pharmacol Rev , vol.57 , pp. 217-252
    • Mollace, V.1    Muscoli, C.2    Masini, E.3    Cuzzocrea, S.4    Salvemini, D.5
  • 29
    • 0035463112 scopus 로고    scopus 로고
    • Vascular remodeling in hypertension: Roles of apoptosis, inflammation, and fibrosis
    • Intengan HD, Schiffrin EL. Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis. Hypertension 2001;38:581-587.
    • (2001) Hypertension , vol.38 , pp. 581-587
    • Intengan, H.D.1    Schiffrin, E.L.2
  • 31
    • 0035344441 scopus 로고    scopus 로고
    • Differential effect of chronic antihypertensive treatment on vascular smooth muscle cell phenotype in spontaneously hypertensive rats
    • Bravo R, Somoza B, Ruiz-Gayo M, González C, Ruilope LM, Fernández-Alfonso MS. Differential effect of chronic antihypertensive treatment on vascular smooth muscle cell phenotype in spontaneously hypertensive rats. Hypertension 2001;37:E4-E10.
    • (2001) Hypertension , vol.37
    • Bravo, R.1    Somoza, B.2    Ruiz-Gayo, M.3    González, C.4    Ruilope, L.M.5    Fernández-Alfonso, M.S.6
  • 33
    • 0030925088 scopus 로고    scopus 로고
    • Multiple polyamine regulatory pathways control compensatory cardiovascular hypertrophy in coarctation hypertension
    • Lipke DW, Newman PS, Tofiq S, Guo H, Arcot SS, Aziz SM et al. Multiple polyamine regulatory pathways control compensatory cardiovascular hypertrophy in coarctation hypertension. Clin Exp Hypertens 1997;19:269-295.
    • (1997) Clin Exp Hypertens , vol.19 , pp. 269-295
    • Lipke, D.W.1    Newman, P.S.2    Tofiq, S.3    Guo, H.4    Arcot, S.S.5    Aziz, S.M.6
  • 36
    • 14644401767 scopus 로고    scopus 로고
    • Different involvement of extracellular matrix components in small and large arteries during chronic NO synthase inhibition
    • Bouvet C, Gilbert LA, Girardot D, deBlois D, Moreau P. Different involvement of extracellular matrix components in small and large arteries during chronic NO synthase inhibition. Hypertension 2005;45:432-437.
    • (2005) Hypertension , vol.45 , pp. 432-437
    • Bouvet, C.1    Gilbert, L.A.2    Girardot, D.3    Deblois, D.4    Moreau, P.5
  • 37
    • 0026624939 scopus 로고
    • Endothelium-dependent regulation of resistances arteries: Alterations with aging and hypertension
    • Lüscher TF, Dohi Y, Tschudi M. Endothelium-dependent regulation of resistances arteries: alterations with aging and hypertension. J Cardiovasc Pharmacol 1992;19: S34-S42.
    • (1992) J Cardiovasc Pharmacol , vol.19
    • Lüscher, T.F.1    Dohi, Y.2    Tschudi, M.3
  • 38
    • 53849086508 scopus 로고    scopus 로고
    • Assessment of arterial stiffness, a translational medicine biomarker system for evaluation of vascular risk
    • Wang X, Keith JC Jr, Struthers AD, Feuerstein GZ. Assessment of arterial stiffness, a translational medicine biomarker system for evaluation of vascular risk. Cardiovasc Ther 2008;26:214-223.
    • (2008) Cardiovasc Ther , vol.26 , pp. 214-223
    • Wang, X.1    Keith Jr., J.C.2    Struthers, A.D.3    Feuerstein, G.Z.4
  • 39
    • 34250819965 scopus 로고    scopus 로고
    • Isolated systolic hypertension is characterized by increased aortic stiffness and endo-thelial dysfunction
    • Wallace SM, Yasmin, McEniery CM, Mäki-Petäjä KM, Booth AD, Cockcroft JR et al. Isolated systolic hypertension is characterized by increased aortic stiffness and endo-thelial dysfunction. Hypertension 2007;50:228-233.
    • (2007) Hypertension , vol.50 , pp. 228-233
    • Wallace, S.M.1    Yasmin McEniery, C.M.2    Mäki-Petäjä, K.M.3    Booth, A.D.4    Cockcroft, J.R.5
  • 40
    • 0033066488 scopus 로고    scopus 로고
    • Endothelin and mechanical properties of the carotid artery in Wistar-Kyoto and spontaneously hypertensive rats
    • Marano G, Grigioni M, Palazzesi S, Ferrari AU. Endothelin and mechanical properties of the carotid artery in Wistar-Kyoto and spontaneously hypertensive rats. Cardio-vasc Res 1999;41:701-707.
    • (1999) Cardio-vasc Res , vol.41 , pp. 701-707
    • Marano, G.1    Grigioni, M.2    Palazzesi, S.3    Ferrari, A.U.4
  • 41
    • 0035678978 scopus 로고    scopus 로고
    • Pulse pressure, endothelium function, and arterial stiffness in spontaneously hypertensive rats
    • Safar M, Chamiot-Clerc P, Dagher G, Renaud JF. Pulse pressure, endothelium function, and arterial stiffness in spontaneously hypertensive rats. Hypertension 2001;38: 1416-1421.
    • (2001) Hypertension , vol.38 , pp. 1416-1421
    • Safar, M.1    Chamiot-Clerc, P.2    Dagher, G.3    Renaud, J.F.4
  • 43
    • 67349161080 scopus 로고    scopus 로고
    • Characterization of arginase 1 gene polymorphisms in the Algerian population and association with blood pressure
    • Meroufel D, Dumont J, Médiène-Benchekor S, Benhammamouch S, Ducimetière P, Cottel D et al. Characterization of arginase 1 gene polymorphisms in the Algerian population and association with blood pressure. Clin Biochem 2009;42:1178-1182.
    • (2009) Clin Biochem , vol.42 , pp. 1178-1182
    • Meroufel, D.1    Dumont, J.2    Médiène-Benchekor, S.3    Benhammamouch, S.4    Ducimetière, P.5    Cottel, D.6
  • 44
    • 34548216816 scopus 로고    scopus 로고
    • Association of arginase 1 gene polymorphisms with the risk of myocardial infarction and common carotid intima media thickness
    • Dumont J, Zureik M, Cottel D, Montaye M, Ducimetière P, Amouyel P et al. Association of arginase 1 gene polymorphisms with the risk of myocardial infarction and common carotid intima media thickness. J Med Genet 2007;44:526-531.
    • (2007) J Med Genet , vol.44 , pp. 526-531
    • Dumont, J.1    Zureik, M.2    Cottel, D.3    Montaye, M.4    Ducimetière, P.5    Amouyel, P.6


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