Effect of genetic variant (rs11887534) in ABCG8 gene in coronary artery disease and response to atorvastatin therapy

Disease Markers

Volumn 28, Issue 5, 2010, Pages 307-313

  Srivastava, Anshika ^a   Garg, Naveen ^a   Srivastava, Anvesha ^a   Srivastava, Kshitij ^a   Mittal, Balraj ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

ABCG8; Atorvastatin therapy; Coronary artery disease; PCR RFLP; polymorphism

Indexed keywords

ATORVASTATIN; ABC TRANSPORTER; ABCG8 PROTEIN, HUMAN; HEPTANOIC ACID DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT; LIPID; PYRROLE DERIVATIVE;

ABCG8 GENE; ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE PREDISPOSITION; DNA POLYMORPHISM; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TREATMENT RESPONSE; CASE CONTROL STUDY; COMPARATIVE STUDY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; PATHOLOGY; RISK FACTOR; TREATMENT OUTCOME;

ANTICHOLESTEREMIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEPTANOIC ACIDS; HUMANS; LIPIDS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PYRROLES; RISK FACTORS; TREATMENT OUTCOME;

EID: 77954806913     PISSN: 02780240     EISSN: None     Source Type: Journal    
DOI: 10.3233/DMA-2010-0710     Document Type: Article

References (22)

1. R. Agah and E.J. Topol, Genetic testing for coronary heart disease: the approaching frontier, Expert Review of Molecular Diagnostics 2 (2002), 448-460.
2. K.E. Berge, H. Tian, G.A. Graf, L.Yu, N.V. Grishin, J. Schultz, P. Kwiterovich, B. Shan, R. Barnes and H.H. Hobbs, Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters, Science 290 (2000), 1771-1775.
3. K.E. Berge, K. von Bergmann, D. Lutjohann, R. Guerra, S.M. Grundy, H.H. Hobbs and J.C. Cohen, Heritability of plasma noncholesterol sterols and relationship to DNAsequence polymorphism in ABCG5 and ABCG8, J. Lipid Res 43 (2002), 486-494.
4. A.K. Bhattacharyya, W.E. Connor, D.S. Lin, M.M. McMurry and R.S. Shulman, Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool of sitosterol in patients with sitosterolemia and xanthomatosis, Arterioscler Thromb 11 (1991), 1287-1294.
5. S. Buch, C. Schafmayer, H. Volzke, C. Becker, A. Franke, H. von Eller-Eberstein, C. Kluck, I. Bassmann, M. Brosch, F. Lammert and others, A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease, Nat Genet 39 (2007), 995-999.
6. G.A. Colditz, M.J. Stampfer, W.C. Willett, B. Rosner, F.E. Speizer and C.H. Hennekens, A prospective study of parental history of myocardial infarction and coronary heart disease in women, Am J Epidemiol 123 (1986), 48-58.
7. H. Gylling, M. Hallikainen, J. Pihlajamaki, J. Agren, M. Laakso, R.A. Rajaratnam, R. Rauramaa and T.A. Miettinen, Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity, J Lipid Res 45 (2004), 1660-1665.
8. R. Johnson, P. McNutt, S. MacMahon and R. Robson, Use of the Friedewald Formula to Estimate LDL-Cholesterol in Patients with Chronic Renal Failure on Dialysis, Clin Chem 43 (1997), 2183-2184.
9. K. Kajinami, M.E. Brousseau, C. Nartsupha, J.M. Ordovas and E.J. Schaefer, ATP binding cassette transporter G5 and G8 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin, J Lipid Res 45 (2004), 653-656. (Pubitemid 38405671)
10. K.C. Koeijvoets, J.B. van der Net, G.M. Dallinga-Thie, E.W. Steyerberg, R.P. Mensink, J.J. Kastelein, E.J. Sijbrands and J. Plat, ABCG8 gene polymorphisms, plasma cholesterol concentrations, and risk of cardiovascular disease in familial hypercholesterolemia, Atherosclerosis 204 (2009), 453-458.
11. M.H. Lee, K. Lu, S. Hazard, H. Yu, S. Shulenin, H. Hidaka, H. Kojima, R. Allikmets, N. Sakuma, R. Pegoraro and others, Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption, Nat Genet 27 (2001), 79-83.
12. D. Lewis, Q. Wang and E.J. Topol, Ischaemic heart disease, Nature Encyclopedia of Life Sciences 10 (2002), 508-515.
13. A.J. Lusis, R. Mar and P.I. Pajukanta, Genetics of atherosclerosis, Annual Review of Genomics and Human Genetics 5 (2004), 189-218.
14. J.J. McCarthy, A. Parker, R. Salem, D.J. Moliterno, Q. Wang, E.F. Plow, S. Rao, G. Shen, W.J. Rogers, L.K. Newby and others, Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes, J Med Genet 41 (2004), 334-341.
15. S.A. Miller, D.D. Dykes and H.F. Polesky, A simple salting out procedure for extracting DNAfrom human nucleated cells, Nucl Acids Res 16 (1988), 1215.
16. G. Shen, S.R. Archacki and Q.Wang, The molecular genetics of coronary artery disease and myocardial infarction, Acute Coronary Syndrome 6 (2004), 129-141.
17. J. Slack and K.A. Evans, The increased risk of death from ischaemic heart disease in first degree relatives of 121 men and 96 women with ischaemic heart disease, J Med Genet 3 (1966), 239-257.
18. A. Srivastava, S. Tulsyan, S.N. Pandey, G. Choudhuri and B. Mittal, Single nucleotide polymorphism in the ABCG8 trans porter gene is associated with gallbladder cancer susceptibility, Liver Int 29 (2009), 831-837.
19. J. Stefkova, R. Poledne and J.A. Hubacek, ATP-binding cassette (ABC) transporters in human metabolism and diseases, Physiol Res 53 (2004), 235-243.
20. Q. Wang and R.E. Pyeritz, Molecular genetics of cardiovascular disease, in: Textbook of Cardiovascular Medicine, E.J. Topol, ed., edn 1. New York: Lippincott Williams & Wilkins, (2000), pp. 1-12.
21. X. Wang, N. Ishimori, R. Korstanje, J. Rollins and B. Paigen, Identifying Novel Genes for Atherosclerosis through, Mouse- Human Comparative Genetics 77 (2005), 1-15.
22. L. Yu, R.E. Hammer, J. Li-Hawkins, K. Von Bergmann, D. Lutjohann, J.C. Cohen and H.H. Hobbs, Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion, Proc Natl Acad Sci U S A 99 (2002), 16237-16242.