Clinical analysis of elderly patients with elderly-onset type 2 diabetes mellitus in china: Assessment of appropriate therapy

Journal of International Medical Research

Volumn 38, Issue 3, 2010, Pages 1134-1141

  Wang, Y ^a   Qin, M Z ^a   Liu, Q ^a   Chang, Z W ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Elderly patients; Glycaemic control; Glycosylated haemoglobin; Type 2 diabetes mellitus

Indexed keywords

ACARBOSE; ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; HEMOGLOBIN A1C; HYDROCHLOROTHIAZIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; METFORMIN; NATEGLINIDE; NITRIC ACID DERIVATIVE; ORAL ANTIDIABETIC AGENT; REPAGLINIDE; ROSIGLITAZONE; ANTIDIABETIC AGENT; GLYCOSYLATED HEMOGLOBIN;

AGED; ALBUMINURIA; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; CHINA; COMORBIDITY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES CONTROL; DIABETIC ANGIOPATHY; DIABETIC HYPERTENSION; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; DIASTOLIC BLOOD PRESSURE; DISEASE SEVERITY; FEMALE; FOOT DISEASE; GERIATRIC PATIENT; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HUMAN; ISCHEMIC HEART DISEASE; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MICROANGIOPATHY; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; PATIENT ASSESSMENT; SYSTOLIC BLOOD PRESSURE; TRANSIENT ISCHEMIC ATTACK; WAIST CIRCUMFERENCE; ADULT; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DRUG COMBINATION; HYPERGLYCEMIA; INSULIN RESISTANCE; MIDDLE AGED; PATHOLOGY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; CHINA; COMORBIDITY; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DRUG THERAPY, COMBINATION; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED;

EID: 77954794761     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001003800342     Document Type: Article

References (27)

1. Wildman RP, Gu D, Muntner P, et al: Trends in overweight and obesity in Chinese adults: between 1991 and 1999-2000. Obesity (Silver Spring) 2008; 16: 1448-1453.
2. King H, Aubert RE, Herman WH: Global burden of diabetes. 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998; 21: 1414-1431.
3. Gu D, Reynolds K, Duan X, et al: Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA). Diabetologia 2003; 46: 1190-1198.
4. Wang L, Kong L, Wu F, et al: Preventing chronic diseases in China. Lancet 2005; 366: 1821-1824.
5. Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of aWHO consultation. Diabet Med 1998; 15: 539-553.
6. Matthews DR, Hosker JP, Rudenski AS, et al: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
7. Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31-41.
8. Davidson MB: The effect of aging on carbohydrate metabolism: a review of the English literature and a practical approach to the diagnosis of diabetes mellitus in the elderly. Metabolism 1979; 28: 688-705.
9. Haffner SM, Miettinen H, Stern MP: The homeostasis model in the San Antonio heart study. Diabetes Care 1997; 20: 1087-1092.
10. de Aguiar LG, Bahia LR, Villela N, et al: Metformin improves endothelial vascular reactivity in first-degree relatives of type 2 diabetic patients with metabolic syndrome and normal glucose tolerance. Diabetes Care 2006; 29: 1083-1089.
11. Goldstein DE, Little RR, Lorenz RA, et al: Tests of glycemia in diabetes. Diabetes Care 2004; 27: 1761-1773.
12. Gerstein HC, Riddle MC, Kendall DM, et al for the ACCORD Study Group: Glycemia treatment strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Am J Cardiol 2007; 99(12 suppl): S34-S43.
13. Gerstein HC, Miller ME, Byington RP, et al: Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008; 358: 2545-2559.
14. Home P: Safety of very tight blood glucose control in type 2 diabetes. BMJ 2008; 336: 458-459.
15. Bi Y, Yan JH, Liao ZH, et al: Inadequate glycaemic control and antidiabetic therapy among inpatients with type 2 diabetes in Guangdong Province of China. Chin Med J(Engl) 2008; 121: 677-681.
16. Ko GT, So WY, Tong PC, et al: Effect of interactions between C peptide and insulin treatment on clinical outcomes among patients with type 2 diabetes mellitus. CMAJ 2009; 180: 919-926.
17. Calvert MJ, McManus RJ, Freemantle N: Management of type 2 diabetes with multiple oral hypoglycaemic agents or insulin in primary care: retrospective cohort study. Br J Gen Pract 2007; 57: 455-460.
18. Yurgin N, Secnik K, Lage MJ: Antidiabetic prescriptions and glycemic control in German patients with type 2 diabetes mellitus: a retrospective database study. Clin Ther 2007; 29: 316-325.
19. A desktop guide to type 2 diabetes mellitus. European Diabetes Policy Group 1999. Diabet Med 1999; 16: 716-730.
20. Frye RL, August P, Brooks MM, et al: A randomized trial of therapies for type 2 diabetes and coronary artery disease. N Engl J Med 2009; 360: 2503-2515.
21. United Kingdom Prospective Diabetes Study Group: United Kingdom Prospective Diabetes Study 24: a 6-year, randomized, controlled trial comparing sulfonylurea, insulin, and metformin therapy in patients with newly diagnosed type 2 diabetes that could not becontrolled with diet therapy. Ann Intern Med 1998; 128: 165-175.
22. Tseng M, Hernandez T: Comparison of intakes of US Chinese women based on food frequency and 24-hour recall data. J Am Diet Assoc 2005; 105: 1145-1148.
23. Johnston PS, Lebovitz HE, Coniff RF, et al: Advantages of α-glucosidase inhibition as monotherapy in elderly type 2 diabetic patients. J Clin Endocrinol Metab 1998; 83: 1515-1522.
24. Pan CY: Reducing the risk of type 2 diabetes: early identification of high-risk individuals and treatment with acarbose. Curr Diabetes Rev 2007; 3: 141-148.
25. Vischer UM, Bauduceau B, Bourdel-Marchasson I, et al: A call to incorporate the prevention and treatment of geriatric disorders in the management of diabetes in the elderly. Diabetes Metab 2009; 35: 168-177.
26. Wang JB, Guan J, Shen J, et al: Insulin increases shedding of syndecan-1 in the serum of patients with type 2 diabetes mellitus. Diabetes Res Clin Pract 2009; 86: 83-88.
27. Gill GV, Woodward A, Pradhan S, et al: Intensified treatment of type 2 diabetes-positive effects on blood pressure, but not glycaemic control. QJM 2003; 96: 833-836.