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Volumn 30, Issue 3, 2010, Pages 519-531

Preimplantation genetic testing: Indications and controversies

Author keywords

Embryo biopsy; Embryo research; In vitro fertilization; Preimplantation genetic diagnosis; Preimplantation genetic screening; Preimplantation genetic testing

Indexed keywords

BETA THALASSEMIA; CHROMOSOME MOSAICISM; CYSTIC FIBROSIS; DIAGNOSTIC ACCURACY; GENETIC COUNSELING; GENETIC SCREENING; GENOME ANALYSIS; HEALTH CARE ACCESS; HEALTH CARE POLICY; HUMAN; HUNTINGTON CHOREA; MYOTONIC DYSTROPHY; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; REVIEW; SICKLE CELL ANEMIA; EMBRYO RESEARCH; FEMALE; PREGNANCY;

EID: 77954784751     PISSN: 02722712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cll.2010.04.008     Document Type: Review
Times cited : (20)

References (75)
  • 1
    • 0025307919 scopus 로고
    • Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification
    • Handyside A.H., Kontogianni E.H., Hardy K., et al. Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification. Nature 1990, 344(6268):768-770.
    • (1990) Nature , vol.344 , Issue.6268 , pp. 768-770
    • Handyside, A.H.1    Kontogianni, E.H.2    Hardy, K.3
  • 2
    • 67651100796 scopus 로고    scopus 로고
    • ESHRE PGD Consortium data collection IX: cycles from January to December 2006 with pregnancy follow-up to October 2007
    • Goossens V., Harton G., Moutou C., et al. ESHRE PGD Consortium data collection IX: cycles from January to December 2006 with pregnancy follow-up to October 2007. Humanit Rep 2009, 24(8):1786-1810.
    • (2009) Humanit Rep , vol.24 , Issue.8 , pp. 1786-1810
    • Goossens, V.1    Harton, G.2    Moutou, C.3
  • 3
    • 7244228087 scopus 로고    scopus 로고
    • Genetics: deaf by design
    • Dennis C. Genetics: deaf by design. Nature 2004, 431(7011):894-896.
    • (2004) Nature , vol.431 , Issue.7011 , pp. 894-896
    • Dennis, C.1
  • 4
    • 85006251767 scopus 로고    scopus 로고
    • Designer babies-are they a reality yet? Case report: simultaneous preimplantation genetic diagnosis for Fanconi anaemia and HLA typing for cord blood transplantation
    • Verlinsky Y., Rechitsky S., Schoolcraft W., et al. Designer babies-are they a reality yet? Case report: simultaneous preimplantation genetic diagnosis for Fanconi anaemia and HLA typing for cord blood transplantation. Reprod Biomed Online 2000, 1(2):31.
    • (2000) Reprod Biomed Online , vol.1 , Issue.2 , pp. 31
    • Verlinsky, Y.1    Rechitsky, S.2    Schoolcraft, W.3
  • 5
    • 34547641390 scopus 로고    scopus 로고
    • The development of novel quantification assay for mitochondrial DNA heteroplasmy aimed at preimplantation genetic diagnosis of Leigh encephalopathy
    • Tajima H., Sueoka K., Moon S.Y., et al. The development of novel quantification assay for mitochondrial DNA heteroplasmy aimed at preimplantation genetic diagnosis of Leigh encephalopathy. J Assist Reprod Genet 2007, 24(6):227-232.
    • (2007) J Assist Reprod Genet , vol.24 , Issue.6 , pp. 227-232
    • Tajima, H.1    Sueoka, K.2    Moon, S.Y.3
  • 6
    • 0023320926 scopus 로고
    • Prenatal diagnosis in the human pre-implantation period. Meeting held at the Ciba Foundation on the 13th November 1986
    • Whittingham D.G., Penketh R. Prenatal diagnosis in the human pre-implantation period. Meeting held at the Ciba Foundation on the 13th November 1986. Humanit Rep 1987, 2(3):267-270.
    • (1987) Humanit Rep , vol.2 , Issue.3 , pp. 267-270
    • Whittingham, D.G.1    Penketh, R.2
  • 7
    • 0023874053 scopus 로고
    • Human gene expression first occurs between the four- and eight-cell stages of preimplantation development
    • Braude P., Bolton V., Moore S. Human gene expression first occurs between the four- and eight-cell stages of preimplantation development. Nature 1988, 332(6163):459-461.
    • (1988) Nature , vol.332 , Issue.6163 , pp. 459-461
    • Braude, P.1    Bolton, V.2    Moore, S.3
  • 8
    • 70350786283 scopus 로고    scopus 로고
    • International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009
    • Zegers-Hochschild F., Adamson G.D., de Mouzon J., et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. Fertil Steril 2009, 92(5):1520-1524.
    • (2009) Fertil Steril , vol.92 , Issue.5 , pp. 1520-1524
    • Zegers-Hochschild, F.1    Adamson, G.D.2    de Mouzon, J.3
  • 9
    • 43449117767 scopus 로고    scopus 로고
    • Genetic testing of embryos: practices and perspectives of US in vitro fertilization clinics
    • Baruch S., Kaufman D., Hudson K.L. Genetic testing of embryos: practices and perspectives of US in vitro fertilization clinics. Fertil Steril 2008, 89(5):1053-1058.
    • (2008) Fertil Steril , vol.89 , Issue.5 , pp. 1053-1058
    • Baruch, S.1    Kaufman, D.2    Hudson, K.L.3
  • 11
    • 59449087092 scopus 로고    scopus 로고
    • PGD for monogenic disorders: aspects of molecular biology
    • Spits C., Sermon K. PGD for monogenic disorders: aspects of molecular biology. Prenat Diagn 2009, 29(1):50-56.
    • (2009) Prenat Diagn , vol.29 , Issue.1 , pp. 50-56
    • Spits, C.1    Sermon, K.2
  • 12
    • 56749158457 scopus 로고    scopus 로고
    • ESHRE PGD Consortium data collection VIII: cycles from January to December 2005 with pregnancy follow-up to October 2006
    • Goossens V., Harton G., Moutou C., et al. ESHRE PGD Consortium data collection VIII: cycles from January to December 2005 with pregnancy follow-up to October 2006. Humanit Rep 2008, 23(12):2629-2645.
    • (2008) Humanit Rep , vol.23 , Issue.12 , pp. 2629-2645
    • Goossens, V.1    Harton, G.2    Moutou, C.3
  • 13
    • 34547647630 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis: present and future
    • Fragouli E. Preimplantation genetic diagnosis: present and future. J Assist Reprod Genet 2007, 24(6):201-207.
    • (2007) J Assist Reprod Genet , vol.24 , Issue.6 , pp. 201-207
    • Fragouli, E.1
  • 14
    • 0035958352 scopus 로고    scopus 로고
    • Preimplantation diagnosis for Fanconi anemia combined with HLA matching
    • Verlinsky Y., Rechitsky S., Schoolcraft W., et al. Preimplantation diagnosis for Fanconi anemia combined with HLA matching. JAMA 2001, 285(24):3130-3133.
    • (2001) JAMA , vol.285 , Issue.24 , pp. 3130-3133
    • Verlinsky, Y.1    Rechitsky, S.2    Schoolcraft, W.3
  • 15
    • 77954801819 scopus 로고    scopus 로고
    • Genetic analysis of the embryo
    • Informa, London, D. Gardner, A. Weissman, C. Howles (Eds.)
    • Yaron Y.G.V., Gamzu R., Malcov M. Genetic analysis of the embryo. Textbook of assisted reproductive technologies 2009, 403-416. Informa, London. 3rd edition. D. Gardner, A. Weissman, C. Howles (Eds.).
    • (2009) Textbook of assisted reproductive technologies , pp. 403-416
    • Yaron, Y.G.V.1    Gamzu, R.2    Malcov, M.3
  • 16
    • 44249106640 scopus 로고    scopus 로고
    • PGD gender selection for non-Mendelian disorders with unequal sex incidence
    • Amor D.J., Cameron C. PGD gender selection for non-Mendelian disorders with unequal sex incidence. Humanit Rep 2008, 23(4):729-734.
    • (2008) Humanit Rep , vol.23 , Issue.4 , pp. 729-734
    • Amor, D.J.1    Cameron, C.2
  • 17
    • 0037218690 scopus 로고    scopus 로고
    • Prevalence of autism in a US metropolitan area
    • Yeargin-Allsopp M., Rice C., Karapurkar T., et al. Prevalence of autism in a US metropolitan area. JAMA 2003, 289(1):49-55.
    • (2003) JAMA , vol.289 , Issue.1 , pp. 49-55
    • Yeargin-Allsopp, M.1    Rice, C.2    Karapurkar, T.3
  • 18
    • 0036898330 scopus 로고    scopus 로고
    • Personal desires of patients and social obligations of geneticists: applying preimplantation genetic diagnosis for non-medical sex selection
    • Pennings G. Personal desires of patients and social obligations of geneticists: applying preimplantation genetic diagnosis for non-medical sex selection. Prenat Diagn 2002, 22(12):1123-1129.
    • (2002) Prenat Diagn , vol.22 , Issue.12 , pp. 1123-1129
    • Pennings, G.1
  • 19
    • 45549083981 scopus 로고    scopus 로고
    • ESHRE Capri Workshop Group Genetic aspects of female reproduction
    • ESHRE Capri Workshop Group Genetic aspects of female reproduction. Hum Reprod Update 2008, 14(4):293-307.
    • (2008) Hum Reprod Update , vol.14 , Issue.4 , pp. 293-307
  • 20
    • 33646231307 scopus 로고    scopus 로고
    • Instability of the human genome: mutation and DNA repair
    • Garland Science, New York, T. Strachan, A. Read (Eds.)
    • Instability of the human genome: mutation and DNA repair. Human molecular genetics 3 2004, 316-349. Garland Science, New York. 3rd edition. T. Strachan, A. Read (Eds.).
    • (2004) Human molecular genetics 3 , pp. 316-349
  • 21
    • 0019423856 scopus 로고
    • Sequence and organization of the human mitochondrial genome
    • Anderson S., Bankier A.T., Barrell B.G., et al. Sequence and organization of the human mitochondrial genome. Nature 1981, 290(5806):457-465.
    • (1981) Nature , vol.290 , Issue.5806 , pp. 457-465
    • Anderson, S.1    Bankier, A.T.2    Barrell, B.G.3
  • 22
    • 61849145606 scopus 로고    scopus 로고
    • Preventing transmission of maternally inherited mitochondrial DNA diseases
    • Poulton J., Kennedy S., Oakeshott P., et al. Preventing transmission of maternally inherited mitochondrial DNA diseases. BMJ 2009, 338:b94.
    • (2009) BMJ , vol.338
    • Poulton, J.1    Kennedy, S.2    Oakeshott, P.3
  • 23
    • 0032231467 scopus 로고    scopus 로고
    • Evidence from human oocytes for a genetic bottleneck in an mtDNA disease
    • Marchington D.R., Macaulay V., Hartshorne G.M., et al. Evidence from human oocytes for a genetic bottleneck in an mtDNA disease. Am J Hum Genet 1998, 63(3):769-775.
    • (1998) Am J Hum Genet , vol.63 , Issue.3 , pp. 769-775
    • Marchington, D.R.1    Macaulay, V.2    Hartshorne, G.M.3
  • 24
    • 38649091334 scopus 로고    scopus 로고
    • A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes
    • Cree L.M., Samuels D.C., de Sousa Lopes S.C., et al. A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nat Genet 2008, 40(2):249-254.
    • (2008) Nat Genet , vol.40 , Issue.2 , pp. 249-254
    • Cree, L.M.1    Samuels, D.C.2    de Sousa Lopes, S.C.3
  • 25
    • 70349284435 scopus 로고    scopus 로고
    • Mitochondrial gene replacement in primate offspring and embryonic stem cells
    • Tachibana M., Sparman M., Sritanaudomchai H., et al. Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature 2009, 461(7262):367-372.
    • (2009) Nature , vol.461 , Issue.7262 , pp. 367-372
    • Tachibana, M.1    Sparman, M.2    Sritanaudomchai, H.3
  • 26
    • 33645124221 scopus 로고    scopus 로고
    • Analysis of mtDNA variant segregation during early human embryonic development: a tool for successful NARP preimplantation diagnosis
    • Steffann J., Frydman N., Gigarel N., et al. Analysis of mtDNA variant segregation during early human embryonic development: a tool for successful NARP preimplantation diagnosis. J Med Genet 2006, 43(3):244-247.
    • (2006) J Med Genet , vol.43 , Issue.3 , pp. 244-247
    • Steffann, J.1    Frydman, N.2    Gigarel, N.3
  • 27
    • 54149089885 scopus 로고    scopus 로고
    • PGD to reduce reproductive risk: the case of mitochondrial DNA disorders
    • Bredenoord A.L., Dondorp W., Pennings G., et al. PGD to reduce reproductive risk: the case of mitochondrial DNA disorders. Humanit Rep 2008, 23(11):2392-2401.
    • (2008) Humanit Rep , vol.23 , Issue.11 , pp. 2392-2401
    • Bredenoord, A.L.1    Dondorp, W.2    Pennings, G.3
  • 28
    • 84927121132 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis for single-gene disorders
    • Cambridge University Press, New York, B. Rizk, J. Garcia-Velasco, H. Sallam (Eds.)
    • Moustafa H., Rizk B., Nagy Z. Preimplantation genetic diagnosis for single-gene disorders. Infertility and assisted reproduction 2008, 657-676. Cambridge University Press, New York. B. Rizk, J. Garcia-Velasco, H. Sallam (Eds.).
    • (2008) Infertility and assisted reproduction , pp. 657-676
    • Moustafa, H.1    Rizk, B.2    Nagy, Z.3
  • 29
    • 0025132537 scopus 로고
    • Analysis of the first polar body: preconception genetic diagnosis
    • Verlinsky Y., Ginsberg N., Lifchez A., et al. Analysis of the first polar body: preconception genetic diagnosis. Humanit Rep 1990, 5(7):826-829.
    • (1990) Humanit Rep , vol.5 , Issue.7 , pp. 826-829
    • Verlinsky, Y.1    Ginsberg, N.2    Lifchez, A.3
  • 30
    • 7144254459 scopus 로고    scopus 로고
    • Preimplantation diagnosis of common aneuploidies by the first- and second-polar body FISH analysis
    • Verlinsky Y., Cieslak J., Ivakhnenko V., et al. Preimplantation diagnosis of common aneuploidies by the first- and second-polar body FISH analysis. J Assist Reprod Genet 1998, 15(5):285-289.
    • (1998) J Assist Reprod Genet , vol.15 , Issue.5 , pp. 285-289
    • Verlinsky, Y.1    Cieslak, J.2    Ivakhnenko, V.3
  • 31
    • 4544242963 scopus 로고    scopus 로고
    • Meiotic and mitotic nondisjunction: lessons from preimplantation genetic diagnosis
    • Kuliev A., Verlinsky Y. Meiotic and mitotic nondisjunction: lessons from preimplantation genetic diagnosis. Hum Reprod Update 2004, 10(5):401-407.
    • (2004) Hum Reprod Update , vol.10 , Issue.5 , pp. 401-407
    • Kuliev, A.1    Verlinsky, Y.2
  • 32
    • 0038304527 scopus 로고    scopus 로고
    • Chromosomal abnormalities in a series of 6,733 human oocytes in preimplantation diagnosis for age-related aneuploidies
    • Kuliev A., Cieslak J., Ilkevitch Y., et al. Chromosomal abnormalities in a series of 6,733 human oocytes in preimplantation diagnosis for age-related aneuploidies. Reprod Biomed Online 2003, 6(1):54-59.
    • (2003) Reprod Biomed Online , vol.6 , Issue.1 , pp. 54-59
    • Kuliev, A.1    Cieslak, J.2    Ilkevitch, Y.3
  • 33
    • 0025292815 scopus 로고
    • Preconception genetic diagnosis of cystic fibrosis
    • Strom C.M., Verlinsky Y., Milayeva S., et al. Preconception genetic diagnosis of cystic fibrosis. Lancet 1990, 336(8710):306-307.
    • (1990) Lancet , vol.336 , Issue.8710 , pp. 306-307
    • Strom, C.M.1    Verlinsky, Y.2    Milayeva, S.3
  • 34
    • 0031777523 scopus 로고    scopus 로고
    • Three births after preimplantation genetic diagnosis for cystic fibrosis with sequential first and second polar body analysis
    • Strom C.M., Ginsberg N., Rechitsky S., et al. Three births after preimplantation genetic diagnosis for cystic fibrosis with sequential first and second polar body analysis. Am J Obstet Gynecol 1998, 178(6):1298-1306.
    • (1998) Am J Obstet Gynecol , vol.178 , Issue.6 , pp. 1298-1306
    • Strom, C.M.1    Ginsberg, N.2    Rechitsky, S.3
  • 35
    • 40749140352 scopus 로고    scopus 로고
    • Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis
    • Goossens V., De Rycke M., De Vos A., et al. Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis. Humanit Rep 2008, 23(3):481-492.
    • (2008) Humanit Rep , vol.23 , Issue.3 , pp. 481-492
    • Goossens, V.1    De Rycke, M.2    De Vos, A.3
  • 36
    • 0034512073 scopus 로고    scopus 로고
    • Embryo implantation after biopsy of one or two cells from cleavage-stage embryos with a view to preimplantation genetic diagnosis
    • Van de Velde H., De Vos A., Sermon K., et al. Embryo implantation after biopsy of one or two cells from cleavage-stage embryos with a view to preimplantation genetic diagnosis. Prenat Diagn 2000, 20(13):1030-1037.
    • (2000) Prenat Diagn , vol.20 , Issue.13 , pp. 1030-1037
    • Van de Velde, H.1    De Vos, A.2    Sermon, K.3
  • 37
    • 33749544339 scopus 로고    scopus 로고
    • The analysis of one or two blastomeres for PGD using fluorescence in-situ hybridization
    • Michiels A., Van Assche E., Liebaers I., et al. The analysis of one or two blastomeres for PGD using fluorescence in-situ hybridization. Humanit Rep 2006, 21(9):2396-2402.
    • (2006) Humanit Rep , vol.21 , Issue.9 , pp. 2396-2402
    • Michiels, A.1    Van Assche, E.2    Liebaers, I.3
  • 38
    • 0026474734 scopus 로고
    • Human embryo biopsy on the 2nd day after insemination for preimplantation diagnosis: removal of a quarter of embryo retards cleavage
    • Tarin J.J., Conaghan J., Winston R.M., et al. Human embryo biopsy on the 2nd day after insemination for preimplantation diagnosis: removal of a quarter of embryo retards cleavage. Fertil Steril 1992, 58(5):970-976.
    • (1992) Fertil Steril , vol.58 , Issue.5 , pp. 970-976
    • Tarin, J.J.1    Conaghan, J.2    Winston, R.M.3
  • 39
    • 44349116887 scopus 로고    scopus 로고
    • Blastocyst trophectoderm biopsy and preimplantation genetic diagnosis for familial monogenic disorders and chromosomal translocations
    • McArthur S.J., Leigh D., Marshall J.T., et al. Blastocyst trophectoderm biopsy and preimplantation genetic diagnosis for familial monogenic disorders and chromosomal translocations. Prenat Diagn 2008, 28(5):434-442.
    • (2008) Prenat Diagn , vol.28 , Issue.5 , pp. 434-442
    • McArthur, S.J.1    Leigh, D.2    Marshall, J.T.3
  • 40
    • 55449087440 scopus 로고    scopus 로고
    • Practice Committee of Society for Assisted Reproductive Technique, Practice Committee of American Society for Reproductive Medicine Preimplantation genetic testing: a Practice Committee opinion
    • Practice Committee of Society for Assisted Reproductive Technique, Practice Committee of American Society for Reproductive Medicine Preimplantation genetic testing: a Practice Committee opinion. Fertil Steril 2008, 90:S136.
    • (2008) Fertil Steril , vol.90
  • 41
    • 0035935240 scopus 로고    scopus 로고
    • Reliability of preimplantation diagnosis for single gene disorders
    • Rechitsky S., Verlinsky O., Amet T., et al. Reliability of preimplantation diagnosis for single gene disorders. Mol Cell Endocrinol 2001, 183(Suppl 1):S65-S68.
    • (2001) Mol Cell Endocrinol , vol.183 , Issue.SUPPL 1
    • Rechitsky, S.1    Verlinsky, O.2    Amet, T.3
  • 42
    • 28444435859 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis and screening
    • Kearns W.G., Pen R., Graham J., et al. Preimplantation genetic diagnosis and screening. Semin Reprod Med 2005, 23(4):336-347.
    • (2005) Semin Reprod Med , vol.23 , Issue.4 , pp. 336-347
    • Kearns, W.G.1    Pen, R.2    Graham, J.3
  • 43
    • 2442505031 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis
    • Sermon K., Van Steirteghem A., Liebaers I. Preimplantation genetic diagnosis. Lancet 2004, 363(9421):1633-1641.
    • (2004) Lancet , vol.363 , Issue.9421 , pp. 1633-1641
    • Sermon, K.1    Van Steirteghem, A.2    Liebaers, I.3
  • 44
    • 0026768976 scopus 로고
    • High-sensitive fluorescent DNA sequencing and its application for detection and mass-screening of point mutations
    • Hattori M., Yoshioka K., Sakaki Y. High-sensitive fluorescent DNA sequencing and its application for detection and mass-screening of point mutations. Electrophoresis 1992, 13(8):560-565.
    • (1992) Electrophoresis , vol.13 , Issue.8 , pp. 560-565
    • Hattori, M.1    Yoshioka, K.2    Sakaki, Y.3
  • 45
    • 67449116488 scopus 로고    scopus 로고
    • The causes of misdiagnosis and adverse outcomes in PGD
    • Wilton L., Thornhill A., Traeger-Synodinos J., et al. The causes of misdiagnosis and adverse outcomes in PGD. Humanit Rep 2009, 24(5):1221-1228.
    • (2009) Humanit Rep , vol.24 , Issue.5 , pp. 1221-1228
    • Wilton, L.1    Thornhill, A.2    Traeger-Synodinos, J.3
  • 46
    • 19944432386 scopus 로고    scopus 로고
    • ESHRE PGD Consortium 'Best practice guidelines for clinical preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS)'
    • Thornhill A.R., deDie-Smulders C.E., Geraedts J.P., et al. ESHRE PGD Consortium 'Best practice guidelines for clinical preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS)'. Humanit Rep 2005, 20(1):35-48.
    • (2005) Humanit Rep , vol.20 , Issue.1 , pp. 35-48
    • Thornhill, A.R.1    deDie-Smulders, C.E.2    Geraedts, J.P.3
  • 47
    • 33745935434 scopus 로고    scopus 로고
    • Proof of principle and first cases using preimplantation genetic haplotyping-a paradigm shift for embryo diagnosis
    • Renwick P.J., Trussler J., Ostad-Saffari E., et al. Proof of principle and first cases using preimplantation genetic haplotyping-a paradigm shift for embryo diagnosis. Reprod Biomed Online 2006, 13(1):110-119.
    • (2006) Reprod Biomed Online , vol.13 , Issue.1 , pp. 110-119
    • Renwick, P.J.1    Trussler, J.2    Ostad-Saffari, E.3
  • 48
    • 0031823425 scopus 로고    scopus 로고
    • Assessment of diagnostic quantitative fluorescent multiplex polymerase chain reaction assays performed on single cells
    • Sherlock J., Cirigliano V., Petrou M., et al. Assessment of diagnostic quantitative fluorescent multiplex polymerase chain reaction assays performed on single cells. Ann Hum Genet 1998, 62(Pt 1):9-23.
    • (1998) Ann Hum Genet , vol.62 , Issue.PART 1 , pp. 9-23
    • Sherlock, J.1    Cirigliano, V.2    Petrou, M.3
  • 49
    • 0038825355 scopus 로고    scopus 로고
    • The minisequencing method: an alternative strategy for preimplantation genetic diagnosis of single gene disorders
    • Fiorentino F., Magli M.C., Podini D., et al. The minisequencing method: an alternative strategy for preimplantation genetic diagnosis of single gene disorders. Mol Hum Reprod 2003, 9(7):399-410.
    • (2003) Mol Hum Reprod , vol.9 , Issue.7 , pp. 399-410
    • Fiorentino, F.1    Magli, M.C.2    Podini, D.3
  • 50
    • 0026755807 scopus 로고
    • Whole genome amplification from a single cell: implications for genetic analysis
    • Zhang L., Cui X., Schmitt K., et al. Whole genome amplification from a single cell: implications for genetic analysis. Proc Natl Acad Sci U S A 1992, 89(13):5847-5851.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.13 , pp. 5847-5851
    • Zhang, L.1    Cui, X.2    Schmitt, K.3
  • 51
    • 13444280505 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis and chromosome analysis of blastomeres using comparative genomic hybridization
    • Wilton L. Preimplantation genetic diagnosis and chromosome analysis of blastomeres using comparative genomic hybridization. Hum Reprod Update 2005, 11(1):33-41.
    • (2005) Hum Reprod Update , vol.11 , Issue.1 , pp. 33-41
    • Wilton, L.1
  • 52
    • 33751194901 scopus 로고    scopus 로고
    • Application of array-based comparative genomic hybridization to clinical diagnostics
    • Bejjani B.A., Shaffer L.G. Application of array-based comparative genomic hybridization to clinical diagnostics. J Mol Diagn 2006, 8(5):528-533.
    • (2006) J Mol Diagn , vol.8 , Issue.5 , pp. 528-533
    • Bejjani, B.A.1    Shaffer, L.G.2
  • 53
    • 0033557235 scopus 로고    scopus 로고
    • Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridisation
    • Wells D., Sherlock J.K., Handyside A.H., et al. Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridisation. Nucleic Acids Res 1999, 27(4):1214-1218.
    • (1999) Nucleic Acids Res , vol.27 , Issue.4 , pp. 1214-1218
    • Wells, D.1    Sherlock, J.K.2    Handyside, A.H.3
  • 54
    • 1842532539 scopus 로고    scopus 로고
    • Aneuploidy detection in single cells using DNA array-based comparative genomic hybridization
    • Hu D.G., Webb G., Hussey N. Aneuploidy detection in single cells using DNA array-based comparative genomic hybridization. Mol Hum Reprod 2004, 10(4):283-289.
    • (2004) Mol Hum Reprod , vol.10 , Issue.4 , pp. 283-289
    • Hu, D.G.1    Webb, G.2    Hussey, N.3
  • 55
    • 33646916059 scopus 로고    scopus 로고
    • Single-cell chromosomal imbalances detection by array CGH
    • Le Caignec C., Spits C., Sermon K., et al. Single-cell chromosomal imbalances detection by array CGH. Nucleic Acids Res 2006, 34(9):e68.
    • (2006) Nucleic Acids Res , vol.34 , Issue.9
    • Le Caignec, C.1    Spits, C.2    Sermon, K.3
  • 56
    • 34248678989 scopus 로고    scopus 로고
    • Whole-genome multiple displacement amplification from single cells
    • Spits C., Le Caignec C., De Rycke M., et al. Whole-genome multiple displacement amplification from single cells. Nat Protoc 2006, 1(4):1965-1970.
    • (2006) Nat Protoc , vol.1 , Issue.4 , pp. 1965-1970
    • Spits, C.1    Le Caignec, C.2    De Rycke, M.3
  • 57
    • 33646372472 scopus 로고    scopus 로고
    • Optimization and evaluation of single-cell whole-genome multiple displacement amplification
    • Spits C., Le Caignec C., De Rycke M., et al. Optimization and evaluation of single-cell whole-genome multiple displacement amplification. Hum Mutat 2006, 27(5):496-503.
    • (2006) Hum Mutat , vol.27 , Issue.5 , pp. 496-503
    • Spits, C.1    Le Caignec, C.2    De Rycke, M.3
  • 58
    • 47749092841 scopus 로고    scopus 로고
    • Ethical Issues in Genetic Testing ACOG Committee Opinion No. 410. American College of Obstetricians and Gynecologists
    • Ethical Issues in Genetic Testing ACOG Committee Opinion No. 410. American College of Obstetricians and Gynecologists. Obstet Gynecol 2008, 111:1495-1502.
    • (2008) Obstet Gynecol , vol.111 , pp. 1495-1502
  • 59
    • 66249085561 scopus 로고    scopus 로고
    • The moral obligation to create children with the best chance of the best life
    • Savulescu J., Kahane G. The moral obligation to create children with the best chance of the best life. Bioethics 2009, 23(5):274-290.
    • (2009) Bioethics , vol.23 , Issue.5 , pp. 274-290
    • Savulescu, J.1    Kahane, G.2
  • 60
    • 69149084388 scopus 로고    scopus 로고
    • Providing preimplantation genetic diagnosis in the United Kingdom, The Netherlands and Germany: a comparative in-depth analysis of health-care access
    • Aarden E., Van Hoyweghen I., Vos R., et al. Providing preimplantation genetic diagnosis in the United Kingdom, The Netherlands and Germany: a comparative in-depth analysis of health-care access. Humanit Rep 2009, 24(7):1542-1547.
    • (2009) Humanit Rep , vol.24 , Issue.7 , pp. 1542-1547
    • Aarden, E.1    Van Hoyweghen, I.2    Vos, R.3
  • 61
    • 0038202943 scopus 로고    scopus 로고
    • In focus. Has patient autonomy gone too far? Geneticists' views in 36 nations
    • Wertz D.C., Fletcher J.C., Nippert I., et al. In focus. Has patient autonomy gone too far? Geneticists' views in 36 nations. Am J Bioeth 2002, 2(4):W21.
    • (2002) Am J Bioeth , vol.2 , Issue.4
    • Wertz, D.C.1    Fletcher, J.C.2    Nippert, I.3
  • 62
    • 74449085018 scopus 로고    scopus 로고
    • Fertility patients' views about frozen embryo disposition: results of a multi-institutional U.S. survey
    • Lyerly A.D., Steinhauser K., Voils C., et al. Fertility patients' views about frozen embryo disposition: results of a multi-institutional U.S. survey. Fertil Steril 2010, 93(2):499-509.
    • (2010) Fertil Steril , vol.93 , Issue.2 , pp. 499-509
    • Lyerly, A.D.1    Steinhauser, K.2    Voils, C.3
  • 63
    • 34347375082 scopus 로고    scopus 로고
    • In vitro fertilization with preimplantation genetic screening
    • Mastenbroek S., Twisk M., van Echten-Arends J., et al. In vitro fertilization with preimplantation genetic screening. N Engl J Med 2007, 357(1):9-17.
    • (2007) N Engl J Med , vol.357 , Issue.1 , pp. 9-17
    • Mastenbroek, S.1    Twisk, M.2    van Echten-Arends, J.3
  • 64
    • 56749158460 scopus 로고    scopus 로고
    • Preimplantation genetic screening in women of advanced maternal age caused a decrease in clinical pregnancy rate: a randomized controlled trial
    • Hardarson T., Hanson C., Lundin K., et al. Preimplantation genetic screening in women of advanced maternal age caused a decrease in clinical pregnancy rate: a randomized controlled trial. Humanit Rep 2008, 23(12):2806-2812.
    • (2008) Humanit Rep , vol.23 , Issue.12 , pp. 2806-2812
    • Hardarson, T.1    Hanson, C.2    Lundin, K.3
  • 65
    • 67349224675 scopus 로고    scopus 로고
    • A prospective randomized controlled trial of preimplantation genetic screening in the " good prognosis" patient
    • Meyer L.R., Klipstein S., Hazlett W.D., et al. A prospective randomized controlled trial of preimplantation genetic screening in the " good prognosis" patient. Fertil Steril 2009, 91(5):1731-1738.
    • (2009) Fertil Steril , vol.91 , Issue.5 , pp. 1731-1738
    • Meyer, L.R.1    Klipstein, S.2    Hazlett, W.D.3
  • 66
    • 53749108255 scopus 로고    scopus 로고
    • Prenatal genome testing sparks debate
    • Kuehn B.M. Prenatal genome testing sparks debate. JAMA 2008, 300(14):1637-1639.
    • (2008) JAMA , vol.300 , Issue.14 , pp. 1637-1639
    • Kuehn, B.M.1
  • 67
    • 0018091794 scopus 로고
    • Birth after the reimplantation of a human embryo
    • Steptoe P.C., Edwards R.G. Birth after the reimplantation of a human embryo. Lancet 1978, 2(8085):366.
    • (1978) Lancet , vol.2 , Issue.8085 , pp. 366
    • Steptoe, P.C.1    Edwards, R.G.2
  • 68
    • 34147139883 scopus 로고    scopus 로고
    • Infertility, assisted reproductive technology, and adverse pregnancy outcomes: executive summary of a National Institute of Child Health and Human Development workshop
    • Reddy U.M., Wapner R.J., Rebar R.W., et al. Infertility, assisted reproductive technology, and adverse pregnancy outcomes: executive summary of a National Institute of Child Health and Human Development workshop. Obstet Gynecol 2007, 109(4):967-977.
    • (2007) Obstet Gynecol , vol.109 , Issue.4 , pp. 967-977
    • Reddy, U.M.1    Wapner, R.J.2    Rebar, R.W.3
  • 69
    • 33744542981 scopus 로고    scopus 로고
    • Professional self-regulation for preimplantation genetic diagnosis: experience of the American Society for Reproductive Medicine and other professional societies
    • Simpson J.L., Rebar R.W., Carson S.A. Professional self-regulation for preimplantation genetic diagnosis: experience of the American Society for Reproductive Medicine and other professional societies. Fertil Steril 2006, 85(6):1653-1660.
    • (2006) Fertil Steril , vol.85 , Issue.6 , pp. 1653-1660
    • Simpson, J.L.1    Rebar, R.W.2    Carson, S.A.3
  • 70
    • 34250174541 scopus 로고    scopus 로고
    • IFFS surveillance 07
    • Jones H.W., Cohen J. IFFS surveillance 07. Fertil Steril 2007, 87(4 Suppl 1):S1-67.
    • (2007) Fertil Steril , vol.87 , Issue.4 SUPPL 1
    • Jones, H.W.1    Cohen, J.2
  • 71
    • 13744256716 scopus 로고    scopus 로고
    • Reproductive tourism and the regulatory map
    • Spar D. Reproductive tourism and the regulatory map. N Engl J Med 2005, 352(6):531-533.
    • (2005) N Engl J Med , vol.352 , Issue.6 , pp. 531-533
    • Spar, D.1
  • 72
    • 0037194714 scopus 로고    scopus 로고
    • Insurance coverage and outcomes of in vitro fertilization
    • Jain T., Harlow B.L., Hornstein M.D. Insurance coverage and outcomes of in vitro fertilization. N Engl J Med 2002, 347(9):661-666.
    • (2002) N Engl J Med , vol.347 , Issue.9 , pp. 661-666
    • Jain, T.1    Harlow, B.L.2    Hornstein, M.D.3
  • 73
    • 33748580104 scopus 로고    scopus 로고
    • Human embryonic stem cell lines derived from single blastomeres
    • Klimanskaya I., Chung Y., Becker S., et al. Human embryonic stem cell lines derived from single blastomeres. Nature 2006, 444(7118):481-485.
    • (2006) Nature , vol.444 , Issue.7118 , pp. 481-485
    • Klimanskaya, I.1    Chung, Y.2    Becker, S.3
  • 74
    • 31544441632 scopus 로고    scopus 로고
    • Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders
    • Mateizel I., De Temmerman N., Ullmann U., et al. Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders. Humanit Rep 2006, 21(2):503-511.
    • (2006) Humanit Rep , vol.21 , Issue.2 , pp. 503-511
    • Mateizel, I.1    De Temmerman, N.2    Ullmann, U.3
  • 75
    • 84925563269 scopus 로고    scopus 로고
    • Adam Nash: legally speaking, a happy ending or slippery slope?
    • Crockin S. Adam Nash: legally speaking, a happy ending or slippery slope?. Reprod Biomed Online 2001, 2(1):6-7.
    • (2001) Reprod Biomed Online , vol.2 , Issue.1 , pp. 6-7
    • Crockin, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.