1-Desoxy analog of 2MD: Synthesis and biological activity of (20S)-25-hydroxy-2-methylene-19-norvitamin D3

Journal of Steroid Biochemistry and Molecular Biology

Volumn 121, Issue 1-2, 2010, Pages 51-55

  Sibilska, Izabela ^a,b   Barycka, Katarzyna M ^a   Sicinski, Rafal R ^a,b   Plum, Lori A ^a   DeLuca, Hector F ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WARSAW   (Poland)

Author keywords

19 Norvitamin D; 2MD; Vitamin D analogs; Vitamin D receptor

Indexed keywords

(20) 1ALPHA,25 DIHYDROXY 2 METHYLENE 19 NORVITAMIN D3; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR; 2-METHYLENE-19-NOR-(20S)-1ALPHA,25-DIHYDROXYVITAMIN D3; 25-HYDROXY-2-METHYLENE-19-NORVITAMIN D3; CALCITRIOL; CALCITRIOL RECEPTOR; OXIDE; PHOSPHINE DERIVATIVE; RECOMBINANT PROTEIN;

ALLYLIC REARRANGEMENT; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL DIFFERENTIATION; DRUG ACTIVITY; DRUG SYNTHESIS; HORNER REACTION; HYDROXYLATION; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; RAT; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; ANALOGS AND DERIVATIVES; ANIMAL; BINDING COMPETITION; CHEMISTRY; DRUG DESIGN; DRUG SCREENING; GENETIC TRANSCRIPTION; HL 60 CELL LINE; HUMAN; PROCEDURES; SPRAGUE DAWLEY RAT; SYNTHESIS;

ANIMALS; BINDING, COMPETITIVE; CALCITRIOL; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HL-60 CELLS; HUMANS; MALE; OXIDES; PHOSPHINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCITRIOL; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC;

EID: 77954759653     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.03.063     Document Type: Article

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