메뉴 건너뛰기




Volumn 79, Issue 5-6, 2009, Pages 308-318

Influence of a complex micronutrient supplement on the immune status of elderly individuals

Author keywords

Elderly individuals; Immunity; Immunosenescence; Micronutrients; Na ve T cells

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BIOTIN; BMI1 PROTEIN; C REACTIVE PROTEIN; CALCIUM; CARBONIC ACID; CD45RA ANTIGEN; CD45RO ANTIGEN; CHLORIDE; CHROMIUM; COBALT; CYANOCOBALAMIN; FATTY ACID; FLUORINE; FOLIC ACID; IRON; LINOLENIC ACID; LOW DENSITY LIPOPROTEIN; NICOTINIC ACID; OMEGA 6 FATTY ACID; PANTOTHENIC ACID; PHOSPHOLIPID; PHYTOMENADIONE; PLACEBO; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TRACE ELEMENT; UNINDEXED DRUG; CD45 ANTIGEN; INFLUENZA VACCINE; INTERLEUKIN 2; MESSENGER RNA; PTPRC PROTEIN, HUMAN; VIRUS ANTIBODY;

EID: 77954706977     PISSN: 03009831     EISSN: None     Source Type: Journal    
DOI: 10.1024/0300-9831.79.5.308     Document Type: Article
Times cited : (14)

References (36)
  • 1
    • 0021129720 scopus 로고
    • Immunologic basis for susceptibility to infection in the aged
    • Makinodan, T., James, S.J., Inamizu, T. and Chang, M.P. (1984) Immunologic basis for susceptibility to infection in the aged. Gerontology 30, 279-289. (Pubitemid 14000536)
    • (1984) Gerontology , vol.30 , Issue.5 , pp. 279-289
    • Makinodan, T.1    James, S.J.2    Inamizu, T.3    Chang, M.-P.4
  • 2
    • 0033954496 scopus 로고    scopus 로고
    • Immunity to influenza in the elderly
    • Webster, R.G. (2000) Immunity to influenza in the elderly. Vaccine 18, 1686-1689.
    • (2000) Vaccine , vol.18 , pp. 1686-1689
    • Webster, R.G.1
  • 3
    • 0027973478 scopus 로고
    • The efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trial
    • Govaert, T.M., Thijs, C.T., Masurel, N., Sprenger, M.J., Dinant, G.J. and Knottnerus, J.A. (1994) The efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trial. JAMA 272, 1661-1665.
    • (1994) JAMA , vol.272 , pp. 1661-1665
    • Govaert, T.M.1    Thijs, C.T.2    Masurel, N.3    Sprenger, M.J.4    Dinant, G.J.5    Knottnerus, J.A.6
  • 5
    • 0030035583 scopus 로고    scopus 로고
    • The aging immune system: Primer and prospectus
    • Miller, R.A. (1996) The aging immune system: primer and prospectus. Science 73, 70-74.
    • (1996) Science , vol.73 , pp. 70-74
    • Miller, R.A.1
  • 8
    • 0023039241 scopus 로고
    • Immunologic response in an elderly population with a mean age of 85
    • Murasko, D.M., Nelson, B.J., Silver, R., Matour, D. and Kaye, D. (1986) Immunologic response in an elderly population with a mean age of 85. Am. J. Med. 81, 612-618.
    • (1986) Am. J. Med. , vol.81 , pp. 612-618
    • Murasko, D.M.1    Nelson, B.J.2    Silver, R.3    Matour, D.4    Kaye, D.5
  • 9
    • 0028837645 scopus 로고
    • Reference intervals for human peripheral blood lymphocyte subpopulations from 'healthy' young and aged subjects
    • Stulnig, T., Maczek, C., Bock, G., Majdic, O. and Wick, G. (1995) Reference intervals for human peripheral blood lymphocyte subpopulations from 'healthy' young and aged subjects. Int. Arch. Allergy Immunol. 108, 205-210.
    • (1995) Int. Arch. Allergy Immunol. , vol.108 , pp. 205-210
    • Stulnig, T.1    Maczek, C.2    Bock, G.3    Majdic, O.4    Wick, G.5
  • 10
    • 0028043586 scopus 로고
    • Decline in CD28+ T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenescence
    • Effros, R.B., Boucher, N., Porter, V., Zhu, X., Spaulding, C., Walford, R.L., Kronenberg, M., Cohen, D. and Schächter, F. (1994) Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence. Exp. Gerontol. 29, 601-609.
    • (1994) Exp. Gerontol. , vol.29 , pp. 601-609
    • Effros, R.B.1    Boucher, N.2    Porter, V.3    Zhu, X.4    Spaulding, C.5    Walford, R.L.6    Kronenberg, M.7    Cohen, D.8    Schächter, F.9
  • 11
    • 0026527127 scopus 로고
    • Isoforms of the CD45 common leukocyte antigen family: Markers for human T-cell differentiation
    • Clement, L.T. (1992) Isoforms of the CD45 common leukocyte antigen family: markers for human T-cell differentiation. J. Clin. Immunol. 12, 1-10.
    • (1992) J. Clin. Immunol. , vol.12 , pp. 1-10
    • Clement, L.T.1
  • 13
    • 0019434273 scopus 로고
    • Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans
    • Gillis, S., Kozak, R., Durante, M., and Weksler, M.E. (1981) Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans. J. Clin. Invest. 67, 937-942.
    • (1981) J. Clin. Invest. , vol.67 , pp. 937-942
    • Gillis, S.1    Kozak, R.2    Durante, M.3    Weksler, M.E.4
  • 14
    • 0030860733 scopus 로고    scopus 로고
    • The aging immune system: Primary and secondary alterations of immune reactivity in the elderly
    • Wick, G. and Grubeck-Loebenstein, B. (1997) The aging immune system: primary and secondary alterations of immune reactivity in the elderly. Exp. Gerontol. 32, 401-413.
    • (1997) Exp. Gerontol. , vol.32 , pp. 401-413
    • Wick, G.1    Grubeck-Loebenstein, B.2
  • 15
    • 0020658869 scopus 로고
    • Nutrition, immunity, and infection: Present knowledge and future directions
    • Chandra, R.K. (1983) Nutrition, immunity, and infection: present knowledge and future directions. Lancet 1, 688-691.
    • (1983) Lancet , vol.1 , pp. 688-691
    • Chandra, R.K.1
  • 16
    • 0028789676 scopus 로고
    • Antioxidants and immune response in aged persons: Overview of present evidence
    • Meydani, S.N., Wu, D., Santos, M.S. and Hayek, M.G. (1995) Antioxidants and immune response in aged persons: overview of present evidence. Am. J. Clin. Nutr. 62, S1462-S1476.
    • (1995) Am. J. Clin. Nutr. , vol.62
    • Meydani, S.N.1    Wu, D.2    Santos, M.S.3    Hayek, M.G.4
  • 17
    • 0026487750 scopus 로고
    • Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjects
    • Chandra, R.K. (1992) Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjects. Lancet 340, 1124-1127.
    • (1992) Lancet , vol.340 , pp. 1124-1127
    • Chandra, R.K.1
  • 18
    • 0029061145 scopus 로고
    • Protein undernutrition as the major cause of decreased immune function in the elderly: Clinical and functional implications
    • Lesourd, B. (1995) Protein undernutrition as the major cause of decreased immune function in the elderly: clinical and functional implications. Nutr. Rev. 53, 86-91.
    • (1995) Nutr. Rev. , vol.53 , pp. 86-91
    • Lesourd, B.1
  • 19
    • 0021257034 scopus 로고
    • Antibody affinity and immune complexes after immunization with tetanus toxoid in protein-energy malnutrition
    • Chandra, R.K., Chandra, S. and Gupta, S. (1984) Antibody affinity and immune complexes after immunization with tetanus toxoid in protein-energy malnutrition. Am. J. Clin. Nutr. 40, 131-134.
    • (1984) Am. J. Clin. Nutr. , vol.40 , pp. 131-134
    • Chandra, R.K.1    Chandra, S.2    Gupta, S.3
  • 21
    • 0029801898 scopus 로고    scopus 로고
    • Results of an open study for evaluating the effectiveness and tolerance of adjuvant administration of the ISF nutrient program in HIV positive patients
    • Fuchs, N., Markolin, G., Kuklinski, B., Jäger, R., Zelch, N., Guth, I., Schicka, G. and Neumann, K. (1996) Results of an open study for evaluating the effectiveness and tolerance of adjuvant administration of the ISF nutrient program in HIV positive patients. Wien. Med. Wochenschr. 146, 483-493.
    • (1996) Wien. Med. Wochenschr. , vol.146 , pp. 483-493
    • Fuchs, N.1    Markolin, G.2    Kuklinski, B.3    Jäger, R.4    Zelch, N.5    Guth, I.6    Schicka, G.7    Neumann, K.8
  • 22
    • 0031890443 scopus 로고    scopus 로고
    • The Role of Nutrition in Immunity in the Aged
    • Lesourd, B., Mazari, L. and Ferry, M. (1998) The Role of Nutrition in Immunity in the Aged. Nutr. Rev. 56, 113-125.
    • (1998) Nutr. Rev. , vol.56 , pp. 113-125
    • Lesourd, B.1    Mazari, L.2    Ferry, M.3
  • 23
    • 0029895686 scopus 로고    scopus 로고
    • Thymic involution with ageing
    • George, A.J. and Ritter, M.A. (1996) Thymic involution with ageing. Immunol. Today 17, 267-272.
    • (1996) Immunol. Today , vol.17 , pp. 267-272
    • George, A.J.1    Ritter, M.A.2
  • 24
    • 0031011169 scopus 로고    scopus 로고
    • Increased apoptosis of CD45RO- T cells with aging
    • Herndon, F.J., Hsu, H.C. and Mountz, J.D. (1997) Increased apoptosis of CD45RO- T cells with aging. Mech. Ageing Dev. 94, 123-134.
    • (1997) Mech. Ageing Dev. , vol.94 , pp. 123-134
    • Herndon, F.J.1    Hsu, H.C.2    Mountz, J.D.3
  • 25
    • 0023950743 scopus 로고
    • Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors
    • Nagel, J.E., Chopra, R.K., Chrest, F.J., McCoy, M.T., Schneider, E.L., Holbrook, N.J. and Adler, W.H. (1988) Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors. J. Clin. Invest. 81, 1096-1102.
    • (1988) J. Clin. Invest. , vol.81 , pp. 1096-1102
    • Nagel, J.E.1    Chopra, R.K.2    Chrest, F.J.3    McCoy, M.T.4    Schneider, E.L.5    Holbrook, N.J.6    Adler, W.H.7
  • 26
    • 0029925555 scopus 로고    scopus 로고
    • Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age
    • Rea, I.M., Stewart, M., Campbell, P., Alexander, H.D., Crockard, A.D. and Morris, T.C. (1996) Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age. Gerontology 42, 69-78. (Pubitemid 26110374)
    • (1996) Gerontology , vol.42 , Issue.2 , pp. 69-78
    • Rea, I.M.1    Stewart, M.2    Campbell, P.3    Alexander, H.D.4    Crockard, A.D.5    Morris, T.C.M.6
  • 27
    • 0028522839 scopus 로고
    • Vaccinating elderly people. Protecting from avoidable disease
    • Stein, B.E. (1994) Vaccinating elderly people. Protecting from avoidable disease. Drugs Aging 5, 242-253.
    • (1994) Drugs Aging , vol.5 , pp. 242-253
    • Stein, B.E.1
  • 28
    • 2442640517 scopus 로고    scopus 로고
    • Three journals raise doubt on validity of Canadian studies
    • White, C. (2004)Three journals raise doubt on validity of Canadian studies. BMJ 328, 67.
    • (2004) BMJ , vol.328 , pp. 67
    • White, C.1
  • 29
    • 0036174472 scopus 로고    scopus 로고
    • The humoral response to live and inactivated influenza vaccines administered alone and in combination to young adults and elderly
    • DOI 10.1016/S1386-6532(01)00246-3, PII S1386653201002463
    • Stepanova, L., Naykhin, A., Kolmskog, C., Jonson, G., Barantceva, I., Bichurina, M. and Kubar, O. (2002) The humoral response to live and inactivated influenza vaccines administered alone and in combination to young adults and elderly. J. Clin.Virol. 24, 193-201. (Pubitemid 34154866)
    • (2002) Journal of Clinical Virology , vol.24 , Issue.3 , pp. 193-201
    • Stepanova, L.1    Naykhin, A.2    Kolmskog, C.3    Jonson, G.4    Barantceva, I.5    Bichurina, M.6    Kubar, O.7    Linde, A.8
  • 30
    • 0030581408 scopus 로고    scopus 로고
    • Kinetics of humoral antibody response to trivalent inactivated split influenza vaccine in subjects previously vaccinated or vaccinated for the first time
    • Kunzel, W., Glathe, H., Engelmann, H. and Van Hoecke, C. (1996) Kinetics of humoral antibody response to trivalent inactivated split influenza vaccine in subjects previously vaccinated or vaccinated for the first time. Vaccine 14, 1108-1110.
    • (1996) Vaccine , vol.14 , pp. 1108-1110
    • Kunzel, W.1    Glathe, H.2    Engelmann, H.3    Van Hoecke, C.4
  • 32
    • 0030044473 scopus 로고    scopus 로고
    • Correlation between the antibody response to influenza vaccine and helper T cell subsets in healthy aging
    • Remarque, E.J., Nijhuis, E.W., Hinloopen, B., Nagelkerken, L., van der Velde, E.A. and Ligthart, G.J. (1996) Correlation between the antibody response to influenza vaccine and helper T cell subsets in healthy aging. Vaccine 14, 127-130.
    • (1996) Vaccine , vol.14 , pp. 127-130
    • Remarque, E.J.1    Nijhuis, E.W.2    Hinloopen, B.3    Nagelkerken, L.4    Van Der Velde, E.A.5    Ligthart, G.J.6
  • 35
    • 0034916594 scopus 로고    scopus 로고
    • Diet and cardiovascular diseases
    • Kromhout, D. (2001) Diet and cardiovascular diseases. J. Nutr. Health Aging 5, 144-149.
    • (2001) J. Nutr. Health Aging , vol.5 , pp. 144-149
    • Kromhout, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.