Dihydroartemisinin-piperaquine versus artemether-lumefantrine, in the treatment of uncomplicated Plasmodium falciparum malaria in central Sudan

Annals of Tropical Medicine and Parasitology

Volumn 104, Issue 4, 2010, Pages 319-326

  Adam, I ^a   Salah, M T ^b   Eltahir, H G ^c   Elhassan, A H ^d   Elmardi, K A ^d   Malik, E M ^d  

^a UNIVERSITY OF KHARTOUM   (Sudan)

^b NATIONAL RIBAT UNIVERSITY   (Sudan)

^c Singa Hospital   (Sudan)

^d FEDERAL MINISTRY OF HEALTH   (Sudan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER PLUS BENFLUMETOL; DIHYDROARTEMISININ PLUS PIPERAQUINE; QUININE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; BENFLUMETOL; DIHYDROARTEMISININ; ETHANOLAMINE DERIVATIVE; FLUORENE DERIVATIVE; PIPERAQUINE; QUINOLINE DERIVATIVE;

ABDOMINAL PAIN; ADULT; ARTICLE; CALCULATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; NAUSEA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; SUDAN; TREATMENT FAILURE; TREATMENT RESPONSE; VOMITING; CHILD; DRUG COMBINATION; MALARIA, FALCIPARUM; PRESCHOOL CHILD; PROCEDURES; TREATMENT OUTCOME;

PLASMODIUM FALCIPARUM;

ANTIMALARIALS; ARTEMISININS; CHILD; CHILD, PRESCHOOL; DRUG THERAPY, COMBINATION; ETHANOLAMINES; FLUORENES; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; QUINOLINES; SUDAN; TREATMENT OUTCOME;

EID: 77954702591     PISSN: 00034983     EISSN: 13648594     Source Type: Journal    
DOI: 10.1179/136485910X12743554760144     Document Type: Article

References (22)

1. Adam, I., Ibrahim, M. H., A/Elbasit, I. & Elbashir, M. I. (2004a). Efficacy of sulphadoxine-pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria in a small sample of Sudanese children. East Mediterranean Health Journal, 10, 309-314.
2. Adam, I., Osman, M. E., Elghazali, G., Ahmed, G. I., Gustafson, L. L. & Elbashir, M. I., (2004b). Efficacies of chloroquine, sulphadoxine- pyrimethamine and quinine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan. Annals of Tropical Medicine and Parasitology, 98, 661-666. (Pubitemid 39390069)
3. Adam, I., A/Elbasit, I. E., Idris, S. M., Malik, E. M. & Elbashir, M. I. (2005a). A comparison of the efficacy of artesunate plus sulfadoxine-pyrimethamine with that of sulfadoxine-pyrimethamine alone, in the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan. Annals of Tropical Medicine and Parasitology, 99, 449-455. (Pubitemid 40992389)
4. Adam, I., Salih, I. & Elbashir, M. I. (2005b). Quinine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene, 90, 736-738. (Pubitemid 41150669)
5. Adjuik,M., Babiker, A.,Garner, P.,Olliaro, P., Taylor,W. & White, N. (2004). Artesunate combinations for treatment of malaria: meta-analysis. Lancet, 363, 9-17.
6. Bassat, Q., Mulenga, M., Tinto, H., Piola, P., Borrmann, S., Menéndezm C., Nambozi, M., Valéa, I., Nabasumba, C., Sasi, P., Bacchieri, A., Corsi, M., Ubben, D., Talisuna, A. & D'Alessandro, U. (2009). Dihydroartemisinin-piperaquine and artemether- lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial. PLoS One, 17, e7871.
7. Ezzet, F., van Vugt, M., Nosten, F., Looareesuwan, S. & White, N. J. (2000) Pharmacokinetics and pharmacodynamics of lumefantrine (benflumetol) in acute falciparum malaria. Antimicrobial Agents and Chemotherapy, 44, 697-704.
8. Giha, H. A. (2010). Artemisinin derivatives for treatment of uncomplicated Plasmodium falciparum malaria in Sudan: too early for too much hope. Parasitology Research, 106, 549-552.
9. Malik, E. M., Atta, H. Y., Weis, M., Lang, A., Puta, C. & Lettenmaier, C. (2004). Sudan Roll Back Malaria Consultative Mission: essential actions to support the attainment of the Abuja Targets. Sudan RBM Country Consultative Mission Final Report. 2004. Geneva: Roll Back Malaria Partnership.
10. Nosten, F. & White, N. J. (2007). Artemisinin-based combination treatment of falciparum malaria. American Journal of Tropical Medicine and Hygiene, 7 (Suppl. 6), 181-192.
11. Plowe, C. V., Djimdé, A., Bouare, M., Doumbo, O. & Wellems, T. E. (1995). Pyrimethamine and proguanil resistance conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. American Journal of Tropical Medicine and Hygiene, 5, 565-568.
12. Price, R. N., Dorsey, G. & Nosten, F. (2009). Antimalarial therapies in children from Papua New Guinea. New England Journal of Medicine, 360, 1254.
13. Sagara, I.,Rulisa, S.,Mbacham,W.,Adam, I., Sissoko,K., Maiga, H., Traore, O., Dara, N., Dicko, Y. T., Dicko, A., Djimdé, A., Jansen, F. H. & Doumbo, O. K. (2009). Efficacy and safety of a fixed dose artesunate- sulfamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial. Malaria Journal, 8, 63.
14. Sinclair, D., Zani, B., Donegan, S., Olliaro, P. & Garner, P. (2009). Artemisinin-based Combination Therapy for Treating Uncomplicated Malaria. Cochrane Database of Systematic Reviews 2009. Art. No. CD007483. Chichester, U.K.: John Wiley & Sons
15. Somé, A. F., Séré, Y. Y., Dokomajilar, C., Zongo, I., Rouamba, N., Greenhouse, B., Ouédraogo, J. B. & Rosenthal, P. J. (2010). Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine/ sulfadoxine- pyrimethamine, but not by dihydroartemisinin-piperaquine in Burkina Faso. Antimicrobial Agents and Chemotherapy, 54, 1949- 1954.
16. White, N. J. (2002). The assessment of antimalarial drug efficacy. Trends in Parasitology, 18, 458-464.
17. World Health Organization (1993). A Global Strategy for Malaria Control. Geneva: WHO.
18. World Health Organization (2000). Severe falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 94 (Suppl.), S1-S90.
19. World Health Organization (2003). Assessment and Monitoring of Antimalarial Drug Efficacy for the Treatment of Uncomplicated Falciparum Malaria. Document WHO/HTM/RBM/2003.50. Geneva: WHO.
20. World Health Organization (2010). Guidelines for the Treatment of Malaria, 2nd Edn. Geneva: WHO.
21. Yeka, A., Dorsey, G., Kamya, M. R., Talisuna, A., Lugemwa, M., Rwakimari, J. B., Staedke, S. G., Rosenthal, P. J., Wabwire-Mangen, F. & Bukirwa, H. (2008). Artemether-lumefantrine versus dihydroartemisinin- piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda. PLoS One, 3, e2390.
22. Zwang, J., Ashley, E. A., Karema, C., D'Alessandro, U., Smithuis, F., Dorsey, G., Janssens, B., Mayxay, M., Newton, P., Singhasivanon, P., Stepniewska, K., White, N. J. & Nosten, F. (2009). Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis. PLoS One, 4, e6358.