Antimalarial therapies in children from papua new guinea

New England Journal of Medicine

Volumn 360, Issue 12, 2009, Pages 1254-1255

  Price, Ric N ^a   Dorsey, Grant ^b   Nosten, Francois ^c  

^a MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SHOKLO MALARIA RESEARCH UNIT   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER PLUS BENFLUMETOL; DIHYDROARTEMISININ PLUS PIPERAQUINE; MILK FAT; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ DERIVATIVE; BENFLUMETOL; DIHYDROQUINGHAOSU; ETHANOLAMINE DERIVATIVE; FAT; FLUORENE DERIVATIVE; PIPERAQUINE; QUINOLINE DERIVATIVE;

BISCUIT; BREAD; CHILD; CLINICAL TRIAL; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG EFFICACY; DRUG TREATMENT FAILURE; FAT INTAKE; FOOD DRUG INTERACTION; HUMAN; LETTER; MALARIA; MALARIA FALCIPARUM; MILK; PAPUA NEW GUINEA; PRIORITY JOURNAL; BIOAVAILABILITY; DRUG COMBINATION; NOTE; TREATMENT FAILURE;

ANTIMALARIALS; ARTEMISININS; BIOLOGICAL AVAILABILITY; DRUG THERAPY, COMBINATION; ETHANOLAMINES; FATS; FLUORENES; HUMANS; MALARIA; QUINOLINES; TREATMENT FAILURE;

EID: 62749161438     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc090023     Document Type: Letter

References (5)

1. Karunajeewa HA, Mueller I, Senn M, et al. A trial of combination antimalarial therapies in children from Papua New Guinea. N Engl J Med 2008;359:2545-57.
2. Ratcliff A, Siswantoro H, Kenangalem E, et al. Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison. Lancet 2007;369:757-65.
3. Yeka A, Dorsey G, Kamya MR, et al. Artemether-lumefan-trine versus dihydroartemisinin-piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda. PLoS ONE 2008;3(6):e2390.
4. Ashley EA, McGready R, Hutagalung R, et al. A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, mul-tidrug-resistant falciparum malaria. Clin Infect Dis 2005;41:425-32.
5. Sim IK, Davis TM, Ilett KR Effects of a high-fat meal on the relative oral bioavailability of piperaquine. Antimicrob Agents Chemother 2005;49:2407-11.