메뉴 건너뛰기




Volumn 184, Issue 10, 2010, Pages 5456-5465

Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; LIVER X RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE; ISOPROTEIN; ORPHAN NUCLEAR RECEPTOR;

EID: 77954697899     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902399     Document Type: Article
Times cited : (61)

References (43)
  • 1
    • 0018741501 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro
    • Steinman, R. M., G. Kaplan, M. D. Witmer, and Z. A. Cohn. 1979. Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro. J. Exp. Med. 149: 1-16.
    • (1979) J. Exp. Med. , vol.149 , pp. 1-16
    • Steinman, R.M.1    Kaplan, G.2    Witmer, M.D.3    Cohn, Z.A.4
  • 2
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 3
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: Specialized and regulated antigen processing machines
    • DOI 10.1016/S0092-8674(01)00449-4
    • Mellman, I., and R. M. Steinman. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106: 255-258. (Pubitemid 32772607)
    • (2001) Cell , vol.106 , Issue.3 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 5
    • 0036681640 scopus 로고    scopus 로고
    • Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor gamma
    • Nencioni, A., F. Grünebach, A. Zobywlaski, C. Denzlinger, W. Brugger, and P. Brossart. 2002. Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor gamma. J. Immunol. 169: 1228-1235.
    • (2002) J. Immunol. , vol.169 , pp. 1228-1235
    • Nencioni, A.1    Grünebach, F.2    Zobywlaski, A.3    Denzlinger, C.4    Brugger, W.5    Brossart, P.6
  • 6
    • 0034161714 scopus 로고    scopus 로고
    • 3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna, G., and L. Adorini. 2000. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J. Immunol. 164: 2405-2411. (Pubitemid 30115468)
    • (2000) Journal of Immunology , vol.164 , Issue.5 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 9
    • 3142688053 scopus 로고    scopus 로고
    • Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion
    • Szatmari, I., P. Gogolak, J. S. Im, B. Dezso, E. Rajnavolgyi, and L. Nagy. 2004. Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion. Immunity 21: 95-106.
    • (2004) Immunity , vol.21 , pp. 95-106
    • Szatmari, I.1    Gogolak, P.2    Im, J.S.3    Dezso, B.4    Rajnavolgyi, E.5    Nagy, L.6
  • 10
    • 51949114424 scopus 로고    scopus 로고
    • Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function
    • Szatmari, I., and L. Nagy. 2008. Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function. EMBO J. 27: 2353-2362.
    • (2008) EMBO J. , vol.27 , pp. 2353-2362
    • Szatmari, I.1    Nagy, L.2
  • 11
    • 36148982257 scopus 로고    scopus 로고
    • PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism
    • Szatmari, I., D. Töröcsik, M. Agostini, T. Nagy, M. Gurnell, E. Barta, K. Chatterjee, and L. Nagy. 2007. PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism. Blood 110: 3271-3280.
    • (2007) Blood , vol.110 , pp. 3271-3280
    • Szatmari, I.1    Töröcsik, D.2    Agostini, M.3    Nagy, T.4    Gurnell, M.5    Barta, E.6    Chatterjee, K.7    Nagy, L.8
  • 13
    • 28444455582 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways
    • DOI 10.1182/blood-2004-12-4709
    • Appel, S., V. Mirakaj, A. Bringmann, M. M. Weck, F. Grünebach, and P. Brossart. 2005. PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways. Blood 106: 3888-3894. (Pubitemid 41739028)
    • (2005) Blood , vol.106 , Issue.12 , pp. 3888-3894
    • Appel, S.1    Mirakaj, V.2    Bringmann, A.3    Weck, M.M.4    Grunebach, F.5    Brossart, P.6
  • 14
    • 0028117755 scopus 로고
    • Ubiquitous receptor: A receptor that modulates gene activation by retinoic acid and thyroid hormone receptors
    • Song, C., J. M. Kokontis, R. A. Hiipakka, and S. Liao. 1994. Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors. Proc. Natl. Acad. Sci. USA 91: 10809-10813.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10809-10813
    • Song, C.1    Kokontis, J.M.2    Hiipakka, R.A.3    Liao, S.4
  • 15
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski, B. A., P. J. Willy, T. R. Devi, J. R. Falck, and D. J. Mangelsdorf. 1996. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383: 728-731.
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 17
    • 0029094960 scopus 로고
    • Ubiquitous receptor: Structures, immunocytochemical localization, and modulation of gene activation by receptors for retinoic acids and thyroid hormones
    • Song, C., R. A. Hiipakka, J. M. Kokontis, and S. Liao. 1995. Ubiquitous receptor: structures, immunocytochemical localization, and modulation of gene activation by receptors for retinoic acids and thyroid hormones. Ann. N. Y. Acad. Sci. 761: 38-49.
    • (1995) Ann. N. Y. Acad. Sci. , vol.761 , pp. 38-49
    • Song, C.1    Hiipakka, R.A.2    Kokontis, J.M.3    Liao, S.4
  • 19
    • 34248399632 scopus 로고    scopus 로고
    • Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin
    • Geyeregger, R., M. Zeyda, W. Bauer, E. Kriehuber, M. D. Säemann, G. J. Zlabinger, D. Maurer, and T. M. Stulnig. 2007. Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin. Blood 109: 4288-4295.
    • (2007) Blood , vol.109 , pp. 4288-4295
    • Geyeregger, R.1    Zeyda, M.2    Bauer, W.3    Kriehuber, E.4    Säemann, M.D.5    Zlabinger, G.J.6    Maurer, D.7    Stulnig, T.M.8
  • 22
    • 0038193542 scopus 로고    scopus 로고
    • Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages
    • Castrillo, A., S. B. Joseph, C. Marathe, D. J. Mangelsdorf, and P. Tontonoz. 2003. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J. Biol. Chem. 278: 10443-10449.
    • (2003) J. Biol. Chem. , vol.278 , pp. 10443-10449
    • Castrillo, A.1    Joseph, S.B.2    Marathe, C.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 24
    • 0242361567 scopus 로고    scopus 로고
    • Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism
    • Castrillo, A., S. B. Joseph, S. A. Vaidya, M. Haberland, A. M. Fogelman, G. Cheng, and P. Tontonoz. 2003. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Mol. Cell 12: 805-816.
    • (2003) Mol. Cell , vol.12 , pp. 805-816
    • Castrillo, A.1    Joseph, S.B.2    Vaidya, S.A.3    Haberland, M.4    Fogelman, A.M.5    Cheng, G.6    Tontonoz, P.7
  • 26
    • 67349215164 scopus 로고    scopus 로고
    • Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages
    • Torocsik, D., A. Szanto, and L. Nagy. 2009. Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages. Mol. Aspects Med. 30: 134-152.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 134-152
    • Torocsik, D.1    Szanto, A.2    Nagy, L.3
  • 30
    • 0034623288 scopus 로고    scopus 로고
    • Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
    • Costet, P., Y. Luo, N. Wang, and A. R. Tall. 2000. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J. Biol. Chem. 275: 28240-28245.
    • (2000) J. Biol. Chem. , vol.275 , pp. 28240-28245
    • Costet, P.1    Luo, Y.2    Wang, N.3    Tall, A.R.4
  • 31
    • 0034637128 scopus 로고    scopus 로고
    • ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR
    • Schwartz, K., R. M. Lawn, and D. P. Wade. 2000. ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR. Biochem. Biophys. Res. Commun. 274: 794-802.
    • (2000) Biochem. Biophys. Res. Commun. , vol.274 , pp. 794-802
    • Schwartz, K.1    Lawn, R.M.2    Wade, D.P.3
  • 33
    • 0034640288 scopus 로고    scopus 로고
    • Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols
    • Venkateswaran, A., J. J. Repa, J. M. Lobaccaro, A. Bronson, D. J. Mangelsdorf, and P. A. Edwards. 2000. Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols. J. Biol. Chem. 275: 14700-14707.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14700-14707
    • Venkateswaran, A.1    Repa, J.J.2    Lobaccaro, J.M.3    Bronson, A.4    Mangelsdorf, D.J.5    Edwards, P.A.6
  • 34
    • 0347034082 scopus 로고    scopus 로고
    • Characterization of the human ABCG1 gene: Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein
    • Kennedy, M. A., A. Venkateswaran, P. T. Tarr, I. Xenarios, J. Kudoh, N. Shimizu, and P. A. Edwards. 2001. Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. J. Biol. Chem. 276: 39438-39447.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39438-39447
    • Kennedy, M.A.1    Venkateswaran, A.2    Tarr, P.T.3    Xenarios, I.4    Kudoh, J.5    Shimizu, N.6    Edwards, P.A.7
  • 35
    • 25444529284 scopus 로고    scopus 로고
    • The human ABCG1 gene: Identification of LXR response elements that modulate expression in macrophages and liver
    • Sabol, S. L., H. B. Brewer, Jr., and S. Santamarina-Fojo. 2005. The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver. J. Lipid Res. 46: 2151-2167.
    • (2005) J. Lipid Res. , vol.46 , pp. 2151-2167
    • Sabol, S.L.1    Brewer Jr., H.B.2    Santamarina-Fojo, S.3
  • 36
    • 0037324340 scopus 로고    scopus 로고
    • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
    • Joseph, S. B., A. Castrillo, B. A. Laffitte, D. J. Mangelsdorf, and P. Tontonoz. 2003. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 9: 213-219.
    • (2003) Nat. Med. , vol.9 , pp. 213-219
    • Joseph, S.B.1    Castrillo, A.2    Laffitte, B.A.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 39
    • 73849096869 scopus 로고    scopus 로고
    • Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
    • Villablanca, E. J., L. Raccosta, D. Zhou, R. Fontana, D. Maggioni, A. Negro, F. Sanvito, M. Ponzoni, B. Valentinis, M. Bregni, et al. 2010. Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses. Nat. Med. 16: 98-105.
    • (2010) Nat. Med. , vol.16 , pp. 98-105
    • Villablanca, E.J.1    Raccosta, L.2    Zhou, D.3    Fontana, R.4    Maggioni, D.5    Negro, A.6    Sanvito, F.7    Ponzoni, M.8    Valentinis, B.9    Bregni, M.10
  • 40
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki, A., and R. Medzhitov. 2004. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5: 987-995.
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 41
    • 0742272509 scopus 로고    scopus 로고
    • Toll-like receptors and dendritic cells: For whom the bug tolls
    • Reis e Sousa, C. 2004. Toll-like receptors and dendritic cells: for whom the bug tolls. Semin. Immunol. 16: 27-34.
    • (2004) Semin. Immunol. , vol.16 , pp. 27-34
    • Reis E Sousa, C.1
  • 42
    • 0028978032 scopus 로고
    • Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli
    • Traenckner, E. B., H. L. Pahl, T. Henkel, K. N. Schmidt, S. Wilk, and P. A. Baeuerle. 1995. Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J. 14: 2876-2883.
    • (1995) EMBO J. , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 43
    • 44849141405 scopus 로고    scopus 로고
    • Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men
    • Rigamonti, E., G. Chinetti-Gbaguidi, and B. Staels. 2008. Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men. Arterioscler. Thromb. Vasc. Biol. 28: 1050-1059.
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 1050-1059
    • Rigamonti, E.1    Chinetti-Gbaguidi, G.2    Staels, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.