In vivo bioluminescent imaging of irradiated orthotopic pancreatic cancer xenografts in nonobese diabetic-severe combined immunodeficient mice: A novel method for targeting and assaying efficacy of ionizing radiation

Translational Oncology

Volumn 3, Issue 3, 2010, Pages 153-159

  Lee, Cheong J ^a   Spalding, Aaron C ^b   Ben Josef, Edgar ^b   Wang, Lidong ^a   Simeone, Diane M ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; LUCIFERASE; TUMOR PROMOTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CONTROLLED STUDY; DIABETES MELLITUS; HUMAN; HUMAN CELL; IN VIVO STUDY; IONIZING RADIATION; MOUSE; NONHUMAN; PANCREAS CANCER; PHOTON EMISSION TOMOGRAPHY; RADIATION DOSE; RADIATION INJURY; SCID MOUSE; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT;

EID: 77954687615     PISSN: None     EISSN: 19365233     Source Type: Journal    
DOI: 10.1593/tlo.09184     Document Type: Article

References (16)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, and Thun MJ (2008). Cancer statistics, 2008. CA Cancer J Clin 58, 71-96.
2. Fidler IJ (1995). Modulation of the organ microenvironment for treatment of cancer metastasis.] Natl Cancer Inst 87, 1588-1592.
3. Dumont N and Arteaga CL (2002). The tumor microenvironment: a potential arbitrator of the tumor suppressive and promoting actions of TGFp1. Differentiation 70, 574-582.
4. Dalton WS (1999). The tumor microenvironment as a determinant of drug response and resistance. Drug Resist Updatl, 285-288.
5. Jung YD, Ahmad SA, Akagi Y, Takahashi Y, Liu W, Reinmuth N, Shaheen RM, Fan F, and Ellis LM (2000). Role of the tumor microenvironment in mediating response to anti-angiogenic therapy. Cancer Metastasis Rev 19, 147-157.
6. Mohammad RM, Al-Katib A, Pettit GR, Vaitkevicius VK, Joshi U, Adsay V, Majumdar AP, and Sarkar FH (1998). An orthotopic model of human pancreatic cancer in severe combined immunodeficient mice: potential application for preclinical studies. Clin Cancer Res 4, 887-894.
7. Capella G, Farre L, Villanueva A, Reyes G, Garcia C, Tarafa G, and Lluis F (1999). Orthotopic models of human pancreatic cancer. Ann N Y Acad Sci 880, 103-109.
8. Schwarz RE, McCarty TM, Peralta EA, Diamond DJ, and Ellenhorn JD (1999). An orthotopic in vivo model of human pancreatic cancer. Surgery 126, 562-567.
9. Ziske C, Tiemann K, Schmidt T, Nagaraj S, Marten A, Schmitz V, Clarenbach R, Sauerbruch T, and Schmidt-Wolf IG (2008). Real-time high-resolution compound imaging allows percutaneous initiation and surveillance in an orthotopic murine pancreatic cancer model. Pancreas 36, 146-152.
10. Bouvet M, Wang J, Nardin SR, Nassirpour R, Yang M, Baranov E, Jiang P, Moossa AR, and Hoffman RM (2002). Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Res 62, 1534-1540.
11. Caceres G, Zhu XY, Jiao JA, Zankina R, Aller A, and Andreotti P (2003). Imaging of luciferase and GFP-transfected human tumours in nude mice. Luminescence 18, 218-223.
12. Olivo C, Alblas J, Verweij V, Van Zonneveld AJ, Dhert WJ, and Martens AC (2008). In vivo bioluminescence imaging study to monitor ectopic bone formation by luciferase gene marked mesenchymal stem cells. J Orthop Res 26, 901-909.
13. El Hilali N, Rubio N, Martinez-Villacampa M, and Blanco J (2002). Combined noninvasive imaging and luminometric quantification of luciferase-labeled human prostate tumors and metastases. Lab Invest, 1563-1571.
14. Camphausen K, Purow B, Sproull M, Scott T, Ozawa T, Deen DF, and Tofilon PJ (2005). Orthotopic growth of human glioma cells quantitatively and qualitatively influences radiation-induced changes in gene expression. Cancer Res 65, 10389-10393.
15. Sarkaria JN, Carlson BL, Schroeder MA, Grogan P, Brown PD, Giannini C, Ballman KV, Kitange GJ, Guha A, Pandita A, et al. (2006). Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response. Clin Cancer Res 12, 2264-2271.
16. Freytag SO, Paielli D, Wing M, Rogulski K, Brown S, Kolozsvary A, Seely J, Barton K, Dragovic A, and Kim JH (2002). Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model. IntJ Radiat Oncol BiolPhys54, 873-885.