Tumor growth suppression in vivo by overexpression of the circadian component, PER2

Genes to Cells

Volumn 15, Issue 4, 2010, Pages 351-358

  Miyazaki, Koyomi ^a   Wakabayashi, Miyuki ^a   Hara, Yasuhiro ^a,b   Ishida, Norio ^a,b  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; INTEGRIN RECEPTOR; PER2 PROTEIN; VASCULOTROPIN; CIRCADIAN RHYTHM SIGNALING PROTEIN; PER2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL ADHESION; CELL CYCLE; CELL MOTILITY; CONTROLLED STUDY; GENE OVEREXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE MYC; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOMA; SARCOMA CELL; TUMOR GROWTH; ANIMAL; BIOCHEMISTRY; GENETICS; GROWTH; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; NEOPLASM; PATHOLOGY;

MURINAE;

ANIMALS; BIOCHEMICAL PROCESSES; CELL CYCLE; GROWTH; KILLER CELLS, NATURAL; MICE; MICE, INBRED ICR; NEOPLASMS; PERIOD CIRCADIAN PROTEINS;

EID: 77954684532     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2010.01384.x     Document Type: Article

References (29)

1. Akamatsu, H., Ichihara-Tanaka, K., Ozono, K., Kamiike, W., Matsuda, H. & Sekiguchi, K. (1996) Suppression of transformed phenotypes of human fibrosarcoma cells by overexpression of recombinant fibronectin. Cancer Res. 56, 4541-4546.
2. Akiyama, S.K., Olden, K. & Yamada, K.M. (1995) Fibronectin and integrins in invasion and metastasis. Cancer Metastasis Rev. 14, 173-189.
3. Beier, U.H., Holtmeier, C., Weise, J.B. & Gorogh, T. (2007) Fibronectin suppression in head and neck cancers, inflammatory tissues and the molecular mechanisms potentially involved. Int. J. Oncol. 30, 621-629.
4. Belvin, M.P., Zhou, H. & Yin, J.C. (1999) The Drosophila dCREB2 gene affects the circadian clock. Neuron 22, 777-787.
5. Dean, D.C., Blakeley, M.S., Newby, R.F., Ghazal, P., Hennighausen, L. & Bourgeois, S. (1989) Forskolin inducibility and tissue-specific expression of the fibronectin promoter. Mol. Cell. Biol. 9, 1498-1506.
6. Filipski, E., Delaunay, F., King, V.M., Wu, M.W., Claustrat, B., Grechez-Cassiau, A., Guettier, C., Hastings, M.H. & Francis, L. (2004) Effects of chronic jet lag on tumor progression in mice. Cancer Res. 64, 7879-7885.
7. Filipski, E., King, V.M., Li, X., Granda, T.G., Mormont, M.C., Liu, X., Claustrat, B., Hastings, M.H. & Levi, F. (2002) Host circadian clock as a control point in tumor progression. J. Natl Cancer Inst. 94, 690-697.
8. Fu, L., Pelicano, H., Liu, J., Huang, P. & Lee, C. (2002) The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell 111, 41-50.
9. Gery, S., Komatsu, N., Baldjyan, L., Yu, A., Koo, D. & Koeffler, H.P. (2006) The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells. Mol. Cell 22, 375-382.
10. Gery, S., Virk, R.K., Chumakov, K., Yu, A. & Koeffler, H.P. (2007) The clock gene Per2 links the circadian system to the estrogen receptor. Oncogene 26, 7916-7920.
11. Hara, Y., Onishi, Y., Oishi, K., Miyazaki, K., Fukamizu, A. & Ishida, N. (2009) Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter. Nucleic Acids Res. 37, 1115-1126.
12. Hiserodt, J.C., Laybourn, K.A. & Varani, J. (1985) Laminin inhibits the recognition of tumor target cells by murine natural killer (NK) and natural cytotoxic (NC) lymphocytes. Am. J. Pathol. 121, 148-155.
13. Hocevar, B.A., Brown, T.L. & Howe, P.H. (1999) TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J. 18, 1345-1356.
14. Hua, H., Wang, Y., Wan, C., Liu, Y., Zhu, B., Yang, C., Wang, X., Wang, Z., Cornelissen-Guillaume, G. & Halberg, F. (2006) Circadian gene mPer2 overexpression induces cancer cell apoptosis. Cancer Sci. 97, 589-596.
15. Hynes, R.O. (1973) Alteration of cell-surface proteins by viral transformation and by proteolysis. Proc. Natl Acad. Sci. USA 70, 3170-3174.
16. Ishida, N. (2007) Circadian clock, cancer and lipid metabolism. Neurosci. Res. 57, 483-490.
17. Iurisci, I., Filipski, E., Reinhardt, J., Bach, S., Gianella-Borra-dori, A., Iacobelli, S., Meijer, L. & Levi, F. (2006) Improved tumor control through circadian clock induction by Seliciclib, a cyclin-dependent kinase inhibitor. Cancer Res. 66, 10720-10728.
18. Koyanagi, S., Kuramoto, Y., Nakagawa, H., Aramaki, H., Ohdo, S., Soeda, S. & Shimeno, H. (2003) A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells. Cancer Res. 63, 7277-7283.
19. Kuznetsov, V.A. (1996) "Harpoon" model for cell-cell adhesion and recognition of target cells by the natural killer cells. J. Theor. Biol. 180, 321-342.
20. Matsuo, T., Yamaguchi, S., Mitsui, S., Emi, A., Shimoda, F. & Okamura, H. (2003) Control mechanism of the circadian clock for timing of cell division in vivo. Science 302, 255-259.
21. Nishio, N., Oishi, K. & Machida, K. (2003) SST-2 tumor inoculation is a useful model for studying the antitumor immune response in SHR rat. Environ. Health Prev. Med. 8, 1-5.
22. Oishi, K., Miyazaki, K., Kadota, K., et al. (2003) Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes. J. Biol. Chem. 278, 41519-41527.
23. Reppert, S.M. & Weaver, D.R. (2001) Molecular analysis of mammalian circadian rhythms. Annu. Rev. Physiol. 63, 647-676.
24. Shimao, Y., Nabeshima, K., Inoue, T. & Koono, M. (1999) Role of fibroblasts in HGF / SF-induced cohort migration of human colorectal carcinoma cells: fibroblasts stimulate migration associated with increased fibronectin production via upregulated TGF-beta1. Int. J. Cancer 82, 449-458.
25. Unsal-Kacmaz, K., Mullen, T.E., Kaufmann, W.K. & Sancar, A. (2005) Coupling of human circadian and cell cycles by the timeless protein. Mol. Cell. Biol. 25, 3109-3116.
26. Weaver, D.R. (1998) The suprachiasmatic nucleus: a 25-year retrospective. J. Biol. Rhythms 13, 100-112.
27. Yamamoto, Y., Yagita, K. & Okamura, H. (2005) Role of cyclic mPer2 expression in the mammalian cellular clock. Mol. Cell. Biol. 25, 1912-1921.
28. Yang, X., Wood, P.A., Oh, E.Y., Du-Quiton, J., Ansell, C.M. & Hrushesky, W.J. (2009) Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm. Breast Cancer Res. Treat. 117, 423-431.
29. Young, M.W. & Kay, S.A. (2001) Time zones: a comparative genetics of circadian clocks. Nat. Rev. Genet. 2, 702-715.