Interference between two modulators of N-type (CaV2.2) calcium channel gating demonstrates that ω-conotoxin GVIA disrupts open state gating

Biochimica et Biophysica Acta - Biomembranes

Volumn 1798, Issue 9, 2010, Pages 1821-1828

  Yarotskyy, Viktor ^a,c   Elmslie, Keith S ^a,b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b A T STILL UNIVERSITY   (United States)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

conopeptide; Gating current; Markov model; Modulation; Roscovitine

Indexed keywords

CALCIUM CHANNEL N TYPE; OMEGA CONOTOXIN GVIA; ROSCOVITINE; CACNA1B PROTEIN, HUMAN; CALCIUM CHANNEL BLOCKING AGENT; PURINE DERIVATIVE;

ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; COMPUTER SIMULATION; CONTROLLED STUDY; DRUG MECHANISM; GENETIC TRANSFECTION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NEUROMODULATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROBABILITY; REGULATORY MECHANISM; STATISTICAL MODEL; SURFACE CHARGE; CELL CULTURE; DRUG EFFECTS; HUMAN; PHYSIOLOGY;

CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, N-TYPE; CELLS, CULTURED; HUMANS; ION CHANNEL GATING; OMEGA-CONOTOXIN GVIA; PURINES;

EID: 77954657659     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.05.004     Document Type: Article

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