Cholinergic regulation of striatal Nova mRNAs

Neuroscience

Volumn 169, Issue 2, 2010, Pages 619-627

  Jelen, N ^a   Ule, J ^b   Zivin, M ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Alternative splicing; Kainate; Nova; Pilocarpine; Seizures; Striatum

Indexed keywords

BRAIN PROTEIN; CHOLINERGIC RECEPTOR; KAINIC ACID; LITHIUM CHLORIDE; MESSENGER RNA; NOVA PROTEIN; NOVA1 PROTEIN; NOVA2 PROTEIN; PILOCARPINE; SCOPOLAMINE; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; MALE; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; SEIZURE; UPREGULATION;

ANIMALS; ANTIGENS, NEOPLASM; CORPUS STRIATUM; EXCITATORY AMINO ACID AGONISTS; KAINIC ACID; LITHIUM CHLORIDE; MALE; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; NERVE TISSUE PROTEINS; PILOCARPINE; RATS; RATS, WISTAR; RNA, MESSENGER; RNA-BINDING PROTEINS; SCOPOLAMINE HYDROBROMIDE; SEIZURES;

EID: 77954624100     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.05.013     Document Type: Article

References (39)

1. Al-Tajir G., Starr M.S. Disordered dopamine neurotransmission in the striatum of rats undergoing pilocarpine-induced generalized seizures, as revealed by microdialysis. J Neural Transm Park Dis Dement Sect 1993, 5:89-100.
2. Ben-Ari Y., Cossart R. Kainate, a double agent that generates seizures: two decades of progress. Trends Neurosci 2000, 23:580-587.
3. Bernard V., Normand E., Bloch B. Phenotypical characterization of the rat striatal neurons expressing muscarinic receptor genes. J Neurosci 1992, 9:3591-3600.
4. Bonhaus D.W., Walters J.R., McNamara J.O. Activation of substantia nigra neurons: role in the propagation of seizures in kindled rats. J Neurosci 1986, 6:3024-3030.
5. Bourne J.A., Fosbraey P., Halliday J. Changes in striatal electroencephalography and neurochemistry induced by kainic acid seizures are modified by dopamine receptor antagonists. Eur J Pharmacol 2001, 413:189-198.
6. Buckanovich R.J., Posner J.B., Darnell R.B. Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system. Neuron 1993, 11:657-672.
7. Buckanovich R.J., Yang Y.Y., Darnell R.B. The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies. J Neurosci 1996, 16:1114-1122.
8. Cacheaux L.P., Ivens S., David Y., Lakhter A.J., Bar-Klein G., Shapira M., Heinemann U., Friedman A., Kaufer D. Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis. J Neurosci 2009, 28:8927-8935.
9. Clifford D.B., Olney J.W., Maniotis A., Collins R.C., Zorumski C.F. The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures. Neuroscience 1987, 3:953-968.
10. Danzer S.C., He X., Loepke A.W., McNamara J.O. Structural plasticity of dentate granule cell mossy fibers during the development of limbic epilepsy. Hippocampus 2010, 20:113-124.
11. Dredge B.K., Stefani G., Engelhard C.C., Darnell R.B. Nova autoregulation reveals dual functions in neuronal splicing. EMBO J 2005, 24:1608-1620.
12. Gale K. Role of GABA in the genesis of chemoconvulsant seizures. Toxicol Lett 64/ 1992, 65:417-428.
13. Galvan A., Kuwajima M., Smith Y. Glutamate and GABA receptors and transporters in the basal ganglia: what does their subsynaptic localization reveal about their function?. Neuroscience 2006, 143:351-375.
14. Huang C.S., Shi S.H., Ule J., Ruggiu M., Barker L.A., Darnell R.B., Jan Y.N., Jan L.Y. Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell 2005, 123:105-118.
15. Jacobsson S.O., Sellström A., Persson S.A., Cassel G.E. Correlation between cortical EEG and striatal microdialysis in soman-intoxicated rats. Neurosci Lett 1997, 231:155-158.
16. Jelen N., Ule J., Zivin M., Darnell R.B. Evolution of Nova-dependent splicing regulation in the brain. PLoS Genet 2007, 3:1838-1847.
17. Jensen K.B., Dredge B.K., Stefani G., Zhong R., Buckanovich R.J., Okano H.J., Yang Y.Y., Darnell R.B. Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron 2000, 25:359-371.
18. Kusske J.A. Corticocaudatothalamic interactions in experimental focal epilepsy in the cat. Exp Neurol 1979, 65:616-624.
19. Leite J.P., Garcia-Cairasco N., Cavalheiro E.A. New insights from the use of pilocarpine and kainate models. Epilepsy Res 2002, 50:93-103.
20. Levey A.I., Kitt C.A., Simonds W.F., Price D.L., Brann M.R. Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. J Neurosci 1991, 10:3218-3226.
21. Licatalosi D.D., Mele A., Fak J.J., Ule J., Kayikci M., Chi S.W., Clark T.A., Schweitzer A.C., Blume J.E., Wang X., Darnell J.C., Darnell R.B. HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature 2008, 456:464-469.
22. Lukasiuk K., Dabrowski M., Adach A., Pitkänen A. Epileptogenesis-related genes revisited. Prog Brain Res 2006, 158:223-241.
23. Racine R.J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol 1972, 32:281-294.
24. Ruggiu M., Herbst R., Kim N., Jevsek M., Fak J.J., Mann M.A., Fischbach G., Burden S.J., Darnell R.B. Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing. Proc Natl Acad Sci U S A 2009, 106:3513-3518.
25. Scharfman H.E. The neurobiology of epilepsy. Curr Neurol Neurosci Rep 2007, 7:348-354.
26. Smolders I., Bogaert L., Ebinger G., Michotte Y. Muscarinic modulation of striatal dopamine, glutamate, and GABA release, as measured with in vivo microdialysis. J Neurochem 1997, 68:1942-1948.
27. Sperk G., Lassmann H., Baran H., Kish S.J., Seitelberger F., Hornykiewicz O. Kainic acid induced seizures: neurochemical and histopathological changes. Neuroscience 1983, 4:1301-1315.
28. Tayebati S.K., Di Tullio M.A., Amenta F. Age-related changes of muscarinic cholinergic receptor subtypes in the striatum of Fisher 344 rats. Exp Gerontol 2004, 39:217-223.
29. Turski W.A., Cavalheiro E.A., Schwarz M., Czuczwar S.J., Kleinrok Z., Turski L. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav Brain Res 1983, 9:315-335.
30. Turski L., Ikonomidou C., Turski W.A., Bortolotto Z.A., Cavalheiro E.A. Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse 1989, 3:154-171.
31. Ule J., Jensen K.B., Ruggiu M., Mele A., Ule A., Darnell R.B. CLIP identifies Nova-regulated RNA networks in the brain. Science 2003, 302:1212-1215.
32. Ule J., Ule A., Spencer J., Williams A., Hu J.S., Cline M., Wang H., Clark T., Fraser C., Ruggiu M., Zeeberg B.R., Kane D., Weinstein J.N., Blume J., Darnell R.B. Nova regulates brain-specific splicing to shape the synapse. Nat Genet 2005, 37:844-852.
33. Ule J., Stefani G., Mele A., Ruggiu M., Wang X., Taneri B., Gaasterland T., Blencowe B.J., Darnell R.B. An RNA map predicting Nova-dependent splicing regulation. Nature 2006, 444:580-586.
34. Whiting P.J., Bonnert T.P., McKernan R.M., Farrar S., Le Bourdellès B., Heavens R.P., Smith D.W., Hewson L., Rigby M.R., Sirinathsinghji D.J., Thompson S.A., Wafford K.A. Molecular and functional diversity of the expanding GABA-A receptor gene family. Ann NY Acad Sci 1999, 868:645-653.
35. Yan Z., Flores-Hernandez J., Surmeier D.J. Coordinated expression of muscarinic receptor messenger RNAs in striatal medium spiny neurons. Neuroscience 2001, 103:1017-1024.
36. Yang Y.Y., Yin G.L., Darnell R.B. The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proc Natl Acad Sci U S A 1998, 95:13254-13259.
37. Zaczek R., Nelson M., Coyle J.T. Kainic acid neurotoxicity and seizures. Neuropharmacology 1981, 20:183-189.
38. Zagulska-Szymczak S., Filipkowski R.K., Kaczmarek L. Kainate-induced genes in the hippocampus: lessons from expression patterns. Neurochem Int 2001, 38:485-501.
39. Zivin M., Sprah L., Sket D. The D1 receptor-mediated effects of the ergoline derivative LEK-8829 in rats with unilateral 6-hydroxydopamine lesions. Br J Pharmacol 1996, 119:1187-1196.