Exploring the mechanism of endothelial involvement in acidosis-induced vasodilatation of aortic tissues from normal and diabetic rats

European Journal of Pharmacology

Volumn 642, Issue 1-3, 2010, Pages 99-106

  Yeo, Jian Loong ^a   Tan, Boris Teng Chuan ^a   Achike, Francis I ^a  

^a INTERNATIONAL MEDICAL UNIVERSITY   (Malaysia)

Author keywords

Acidosis; Diabetes mellitus; EDRF; Potassium channels

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CYCLIC GMP; INWARDLY RECTIFYING POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; 4 AMINOPYRIDINE; BARIUM CHLORIDE; BARIUM DERIVATIVE; CHLORIDE; GLIBENCLAMIDE; IBERIOTOXIN; INDOMETACIN; METHYLENE BLUE; N(G) NITROARGININE METHYL ESTER; PEPTIDE; TETRYLAMMONIUM;

ACIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIAL DYSFUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; VASCULAR RING; ANIMAL; AORTA; DRUG EFFECTS; GLUCOSE CLAMP TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM; VASODILATATION;

4-AMINOPYRIDINE; ACIDOSIS; ANIMALS; AORTA; BARIUM COMPOUNDS; CHLORIDES; DIABETES MELLITUS; ENDOTHELIUM, VASCULAR; GLUCOSE CLAMP TECHNIQUE; GLYBURIDE; INDOMETHACIN; MALE; METHYLENE BLUE; NG-NITROARGININE METHYL ESTER; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; TETRAETHYLAMMONIUM; VASODILATION;

EID: 77954621603     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.05.040     Document Type: Article

References (31)

1. Achike F.I., Dai S. Effects of blood gas/pH abnormalities on the cardiovascular actions of verapamil in rats. Clin. Exp. Pharmacol. Physiol. 1990, 17:653-663.
2. Achike F.I., Dai S. Cardiovascular responses to nifedipine in anaesthetised rats with abnormal blood gas/pH levels. Clin. Exp. Pharmacol. Physiol. 1991, 18:223-230.
3. Achike F.I., Dai S., Ogle C.W. Blood pH and the actions of nifedipine on cardiac excitation-contraction coupling. Eur. J. Pharmacol. 1992, 219:369-376.
4. Achike F.I., Dai S., Ogle C.W. Influence of pH changes on the actions of verapamil on vascular excitation-contraction coupling. Environ. Toxicol. Pharmacol. 1996, 1:207-212.
5. Candia S., Garcia M., Latorre R. Mode of action of iberiotoxin, a potent blocker of the large conductance Ca(2+)-activated K+ channel. Biophys. J. 1992, 63:583-590.
6. Feletou M., Vanhoutte P.M. Endothelium-derived hyperpolarising factor. Where are we now?. Arterioscler. Thromb. Vasc. Biol. 2006, 26:1215-1225.
7. Furchgott R.F., Vanhoutte P.M. Endothelium-derived relaxing and contracting factors. FASEB J. 1989, 3:2007-2018.
8. Gaskell W.H. On the tonicity of the heart and blood vessels. J. Physiol. 1880, 3:48-92.
9. Huang A., Sun D., Carroll M.A., Jiang H., Smith C.J., Connetta J.A., Falck J., Shesel E.G., Koller A., Kaley G. EDHF mediates flow-induced dilation in skeletal muscle arterioles of female eNOS-KO mice. Am. J. Physiol. 2001, 280:H2462-H2469.
10. + channels on afferent arteriolar diameter in diabetes mellitus. J. Am. Soc. Neprol. 2000, 11:1199-1207.
11. Ishizaka H., Kuo L. Acidosis-induced coronary arteriolar dilation is mediated by ATP-sensitive potassium channels in vascular smooth muscle. Circ. Res. 1996, 78:50-57.
12. Jackson W.F. Ion channels and vascular tone. Hypertension 2000, 35:173-178.
13. Kersten J.R., Brooks L.A., Dellsperger K.C. Impaired microvascular response to graded coronary occlusion in diabetic and hyperglycaemic dogs. Am. J. Physiol. 1995, 268:H1667-H1674.
14. 2+-activated potassium channels. J. Cereb. Blood Flow Metab. 2003, 23:1227-1238.
15. McKinnon W., Aaronson P.I., Knock G., Graves J., Poston L. Mechanism of lactate-induced relaxation of isolated rat mesenteric resistance arteries. J. Physiol. 1996, 490:783-792.
16. Moncada S., Gryglewski R., Bunting S., Vane J.R. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 1976, 263:663-665.
17. Nelson M.T., Quayle J.M. Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 1995, 268:C799-C822.
18. Nilius B., Droogmans G. Ion channels and their functional role in vascular endothelium. Physiol. Rev. 2001, 81:1415-1459.
19. Niu L.G., Zhang M.S., Liu Y., Xue W.X., Liu D.B., Zhang J., Liang Y.Q. Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries. Eur. J. Pharmacol. 2008, 580:169-174.
20. Palmer R.M.J., Ferrigo A.G., Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987, 327:524-525.
21. Petersson J., Zygmunt P.M., Hogestatt E.D. Characterisation of the potassium channels involved in EDHF-mediated relaxation in cerebral arteries. Br. J. Pharmacol. 1997, 120:1344-1350.
22. Pollock J.S., Fostermann U., Mitchell J.A., Warner T.D., Schmidt H.H., Nakane M., Murad F. Purification and characterisation of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc. Natl. Acad. Sci. U.S.A. 1991, 88:10,480-10,484.
23. Ralevic V., Belai A., Burnstock G. Effects of streptozotocin-diabetes on sympathetic nerve, endothelial and smooth muscle function in the rat mesenteric arterial bed. Eur. J. Pharmacol. 1995, 286:193-199.
24. Rohra D.K., Sharif H.M., Zubairi H.S., Sarfraz K., Ghayur M.N., Gilani A.H. Acidosis-induces relaxation of human internal mammary artery is due to activation of ATP-sensitive potassium channels. Eur. J. Pharmacol. 2005, 514:175-181.
25. Sheetz M.J., King G.L. Molecular understanding of hyperglycaemia's adverse effects for diabetic complications. JAMA 2002, 288:2579-2588.
26. + channel. Circ. Res. 2006, 99:537.
27. Sobey C.G. Potassium channel function in vascular disease. Arterioscler. Thromb. Vasc. Biol. 2001, 21:28-38.
28. Subramaniam G., Achike F.I., Mustafa M.R. Effect of acidosis on the mechanism(s) of insulin-induced vasorelaxation in normal Wistar-Kyoto (WKY) rat aorta. Regul. Pept. 2009, 155:70-75.
29. Tesfamariam B. Free radicals in diabetic endothelial cell dysfunction. Free Radic. Biol. Med. 1994, 16:383-391.
30. Wray S., Smith R.D. Mechanism of action of pH-induced effects on vascular smooth muscle. Mol. Cell. Biochem. 2004, 263:163-172.
31. Ye C.L., Shen B., Ren X.D., Luo R.J., Ding S.Y., Yan F.M., Jiang J.H. An increase in opening of BK(Ca) channels in smooth muscle cells in streptozotocin-induced diabetic mice. Acta Pharmacol. Sin. 2004, 25:744-750.