Large scale screening for haemoglobin disorders in southern Vietnam: Implications for avoidance and management

British Journal of Haematology

Volumn 150, Issue 3, 2010, Pages 359-364

  O'Riordan, Sean ^a,b   Hien, Tran Tinh ^c   Miles, Katie ^b   Allen, Angela ^b   Quyen, Nguyen Ngoc ^a   Hung, Nguyen Quoc ^d   Anh, Do Quang ^e   Tuyen, Luc Nguyen ^f   Khoa, Dao Bach ^a   Thai, Cao Quang ^a   Triet, Dao Minh ^a   Phu, Nguyen Hoan ^a,c   Dunstan, Sarah ^a   Peto, Tim ^b,g   Clegg, John ^b   Farrar, Jeremy ^a,g   Weatherall, David ^b  

^a The Hospital for Tropical Diseases   (Viet Nam)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d Inst Malariology Parasitol E   (Viet Nam)

^e Phuoc Long District Health Centre   (Viet Nam)

^f Khanh Hoa Provincial Malaria Control Programme   (Viet Nam)

^g CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

thalassaemia; thalassaemia; glucose 6 phosphate dehydrogenase deficiency; haemoglobin E; population genetics

Indexed keywords

DNA; FORMAZAN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEMOGLOBIN E; METHYLENE BLUE; PRIMAQUINE;

ALPHA THALASSEMIA; ARTICLE; BETA THALASSEMIA; ETHNIC DIFFERENCE; FEMALE; GENE DELETION; GENE FREQUENCY; GENOTYPE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEMOGLOBIN ANALYSIS; HETEROZYGOSITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; MALE; MASS SCREENING; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; PLASMODIUM VIVAX; PLASMODIUM VIVAX MALARIA; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEX DIFFERENCE; VIET NAM;

ALPHA-THALASSEMIA; BETA-THALASSEMIA; BLOOD SPECIMEN COLLECTION; GENE FREQUENCY; GENOTYPE; GLYCOGEN STORAGE DISEASE TYPE I; HEMOGLOBIN E; HEMOGLOBINOPATHIES; HUMANS; MASS SCREENING; MUTATION; NEEDS ASSESSMENT; PREVALENCE; VIETNAM;

EID: 77954607742     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08237.x     Document Type: Article

References (23)

1. Allison, A.C. (1960) Glucose-6-phosphate dehydrogenase deficiency in red blood cells of East Africans. Nature, 186, 531 532.
2. Ashmun, R.A., Hultquist, D.E. Schultz, J.S. (1986) Kinetic analysis in single, intact cells by microspectrophotometry: evidence for two populations of erythrocytes in an individual heterozygous for glucose-6-phosphate dehydrogenase deficiency. American Journal of Hematology, 23, 311 316.
3. Beutler, E. Baluda, M.C. (1964) The separation of glucose-6-phosphate- dehydrogenase-deficient erythrocytes from the blood of heterozygotes for glucose-6-phosphate-dehydrogenase deficiency. Lancet, 1, 189 192.
4. Christianson, A., Howson, C.P. Modell, B. (2006) March of Dimes Global Report on Birth Defects. March of Dimes Birth Defects Foundation
5. De Silva, S., Fisher, C.A., Premawardhena, A., Lamabadusuriya, S.P., Peto, T.E.A., Perera, G., Old, J.M., Clegg, J.B., Olivieri, N.F. Weatherall, D.J. Sri Lanka Thalassaemia Study Group 2000) Thalassaemia in Sri Lanka: implications for the future health burden of Asian populations. Lancet, 355, 786 791.
6. Flatz, G., Sanguansermsri, T., Sengchanh, S., Horst, D. Horst, J. (2004) The 'hot-spot' of Hb E [beta26(B8)Glu - >Lys] in Southeast Asia: beta-globin anomalies in the Lao Theung population of southern Laos. Hemoglobin, 28, 197 204.
7. Fucharoen, S. Winichagoon, P. (1987) Hemoglobinopathies in Southeast Asia. Hemoglobin, 11, 65 88.
8. Fucharoen, S. Winichagoon, P. (1992) Thalassemia in Southeast Asia: problems and strategy for prevention and control. Southeast Asian Journal of Tropical Medicine and Public Health, 23, 647 655.
9. Fucharoen, S. Winichagoon, P. (1997) Hemoglobinopathies in Southeast Asia: molecular biology and clinical medicine. Hemoglobin, 21, 299 319.
10. Hirono, A., Fujii, H. Miwa, S. (1998) An improved single-step screening method for glucose-6-phosphate dehydrogenase deficiency. Japanese Journal of Tropical Medicine and Hygiene, 26, 1 4.
11. Liu, Y.T., Old, J.M., Miles, K., Fisher, C.A., Weatherall, D.J. Clegg, J.B. (2000) Rapid detection of alpha-thalassaemia deletions and alpha-globin gene triplication by multiplex polymerase chain reactions. British Journal Haematology, 108, 295 299.
12. Livingstone, F.B. (1985) Frequencies of Hemoglobin Variants. Oxford University Press
13. Luzzatto, L., Usanga, E.A., Bienzle, U., Esan, G.F. Fusuan, F.A. (1979) Imbalance in X-chromosome expression: evidence for a human X-linked gene affecting growth of hemopoietic cells. Science, 205, 1418 1420.
14. Mendis, K., Sina, B.J., Marchesini, P. Carter, R. (2001) The neglected burden of Plasmodium vivax malaria. American Journal of Tropical Medicine and Hygiene, 64, 97 106.
15. Modell, B. Darlison, M. (2008) Global epidemiology of haemoglobin disorders and derived service indicators. Bulletin of the World Health Organization, 86, 480 487.
16. Penman, B.S., Pybus, O.G., Weatherall, D.J. Gupta, S. (2009) Why is the sickle cell gene uncommon in the Mediterranean? Proceedings of the National Academy of Sciences of the United States of America, 106, 21242 21246.
17. Singh, H. (1986) Glucose-6-phosphate dehydrogenase deficiency: a preventable cause of mental retardation. British Medical Journal (Clinical research ed.), 292, 397 398.
18. Viprakasit, V., Tanphaichitr, V.S., Pung-Amritt, P., Petrarat, S., Suwantol, L., Fisher, C. Higgs, D.R. (2002) Clinical phenotypes and molecular characterization of Hb H-Pakse disease. Haematologica, 87, 117 125.
19. Wasi, P. (1983) Hemoglobinopathies in Southeast Asia. In : Distribution and Evolution of the Hemoglobin and Globin Loci (ed. by J.E. Bowman pp. 179 209. Elsevier
20. Weatherall, D.J. Clegg, J.B. (2001) The Thalassaemia Syndromes. Blackwell Science
21. Weatherall, D.J., Akinyanju, O., Fucharoen, S., Olivieri, N.F. Musgrove, P. (2006) Inherited Disorders of Hemoglobin. In : Disease Control Priorities in Developing Countries (ed. by D.T. Jamison, J.G. Breman, A.R. Measham, G. Alleyne, M. Claeson, D.B. Evans, P. Jha, A. Mills P. Musgrove pp. 663 680. Oxford University Press and the World Bank
22. White, J.M., Christie, B.S., Nain, D., Daar, S. Higgs, D.R. (1993) Frequency and clinical significance of erythrocyte genetic abnormalities in Omanis. Journal of Medical Genetics, 30, 396 400.
23. Williams, T.N., Mwangi, T.W., Wambua, S., Peto, T.E., Weatherall, D.J., Gupta, S., Recker, M., Penman, B.S., Uyoga, S., Macharia, A., Mwacharo, J.K., Snow, R.W. Marsh, K. (2005) Negative epistasis between the malaria-protective effects of alpha+-thalassemia and the sickle cell trait. Nature Genetics, 37, 1253 1257.