(-)-Epigallocatechin-3-gallate induces apoptosis and suppresses proliferation by inhibiting the human Indian Hedgehog pathway in human chondrosarcoma cells

Journal of Cancer Research and Clinical Oncology

Volumn 136, Issue 8, 2010, Pages 1179-1185

  Tang, Guo Qing ^a   Yan, Tai Qiang ^a   Guo, Wei ^a   Ren, Ting Ting ^a   Peng, Chang Liang ^a   Zhao, Hui ^a   Lu, Xin Chang ^a   Zhao, Fu Long ^a   Han, Xiaoguang ^b  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

Apoptosis; Chondrosarcoma; EGCG; Indian Hedgehog pathway

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; CASPASE 3; EPIGALLOCATECHIN GALLATE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; ANTINEOPLASTIC AGENT; CATECHIN; CELL SURFACE RECEPTOR; DRUG DERIVATIVE; PATCHED RECEPTORS; PRIMER DNA;

APOPTOSIS; ARTICLE; BIOASSAY; CANCER CELL CULTURE; CANCER INHIBITION; CHONDROSARCOMA; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BONE TUMOR; CELL DEATH; CELL DIVISION; CELL SURVIVAL; DRUG EFFECT; GENE AMPLIFICATION; GENETICS; PATHOLOGY;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BONE NEOPLASMS; CATECHIN; CELL DEATH; CELL DIVISION; CELL SURVIVAL; CHONDROSARCOMA; DNA PRIMERS; FLOW CYTOMETRY; GENE AMPLIFICATION; HUMANS; RECEPTORS, CELL SURFACE;

EID: 77954587919     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-010-0765-3     Document Type: Article

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