Exploration of the lysis mechanisms of leukaemic blasts by chimaeric T-cells

Journal of Biomedicine and Biotechnology

Volumn 2010, Issue , 2010, Pages

  Laurin, David ^a,b,c   Marin, Virna ^d   Biagi, Ettore ^d   Pizzitola, Irene ^d   Agostoni, Valentina ^d   Gallot, Géraldine ^b,e   Vié, Henri ^e   Jacob, Marie Christine ^b,c,f   Chaperot, Laurence ^d   Aspord, Caroline ^a,b,c   Plumas, Jol ^e  

^a Etablissement Franais du Sang   (France)

^b INSERM   (France)

^c UNIV GRENOBLE ALPES   (France)

^d SAN GERARDO HOSPITAL   (Italy)

^e HÔTEL DIEU   (France)

^f GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIBODY; CHIMERIC ANTIBODY; CONCANAMYCIN A; DEATH RECEPTOR; EGTAZIC ACID; FAS ANTIBODY; GAMMA INTERFERON; GRANZYME; PERFORIN; T CELL RECEPTOR ZETA; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CD19 ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOPTIVE TRANSFER; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BONE MARROW CELL; CANCER CELL CULTURE; CELL DEATH; CYTOKINE INDUCED KILLER CELL; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; GENETIC ENGINEERING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOTHERAPY; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMID; TARGET CELL; ADOPTIVE IMMUNOTHERAPY; CELL LINE; CELL TRANSFORMATION; FLOW CYTOMETRY; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION;

ANTIGENS, CD19; APOPTOSIS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CYTOKINE-INDUCED KILLER CELLS; FLOW CYTOMETRY; GRANZYMES; HUMANS; IMMUNOTHERAPY, ADOPTIVE; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; PERFORIN; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 77954562380     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2010/234540     Document Type: Article

References (22)

1. Pui C. H., Schrappe M., Ribeiro R. C., Niemeyer C. M., Childhood and adolescent lymphoid and myeloid leukemia Hematology 2004 118 145
2. Loren A. W., Porter D. L., Donor leukocyte infusions for the treatment of relapsed acute leukemia after allogeneic stem cell transplantation Bone Marrow Transplantation 2008 41 5 483 493
3. Biagi E., Marin V., Attianese G. M. P. G., Dander E., D'Amico G., Biondi A., Chimeric T-cell receptors: new challenges for targeted immunotherapy in hematologic malignancies Haematologica 2007 92 3 381 388
4. Pule M. A., Straathof K. C., Dotti G., Heslop H. E., Rooney C. M., Brenner M. K., A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells Molecular Therapy 2005 12 5 933 941
5. Brentjens R. J., Santos E., Nikhamin Y., Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts Clinical Cancer Research 2007 13 18 5426 5435
6. Roessig C., Scherer S. P., Baer A., Targeting CD19 with genetically modified EBV-specific human T lymphocytes Annals of Hematology 2002 81 supplement 2 S42 S43
7. Cooper L. J. N., Al-Kadhimi Z., Serrano L. M., Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1 Blood 2005 105 4 1622 1631
8. Cooper L. J. N., Topp M. S., Serrano L. M., T-cell clones can be rendered specific for CD19: toward the selective augmentation of the graft-versus-B-lineage leukemia effect Blood 2003 101 4 1637 1644
9. Imai C., Iwamoto S., Campana D., Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells Blood 2005 106 1 376 383
10. Marin V., Dander E., Biagi E., Characterization of in vitro migratory properties of anti-CD19 chimeric receptor-redirected CIK cells for their potential use in B-ALL immunotherapy Experimental Hematology 2006 34 9 1219 1229
11. Barry M., Bleackley R. C., Cytotoxic T lymphocytes: all roads lead to death Nature Reviews Immunology 2002 2 6 401 409
12. Kaufmann S. H., Steensma D. P., On the TRAIL of a new therapy for leukemia Leukemia 2005 19 12 2195 2202
13. Igney F. H., Krammer P. H., Death and anti-death: tumour resistance to apoptosis Nature Reviews Cancer 2002 2 4 277 288
14. Chowdhury D., Lieberman J., Death by a thousand cuts: granzyme pathways of programmed cell death Annual Review of Immunology 2008 26 389 420
15. Kagi D., Ledermann B., Burki K., Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice Nature 1994 369 6475 31 37
16. Otten H. G., van Ginkel W. G. J., Hagenbeek A., Petersen E. J., Prevalence and clinical significance of resistance to perforin- and FAS-mediated cell death in leukemia Leukemia 2004 18 8 1401 1405
17. Uno K., Inukai T., Kayagaki N., TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells Blood 2003 101 9 3658 3667
18. Clodi K., Wimmer D., Li Y., Expression of tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors and sensitivity to TRAIL-induced apoptosis in primary B-cell acute lymphoblastic leukaemia cells British Journal of Haematology 2000 111 2 580 586
19. Hombach A., Kohler H., Rappl G., Abken H., Human CD4+ T cells lyse target cells via granzyme/perforin upon circumvention of MHC class II restriction by an antibody-like immunoreceptor Journal of Immunology 2006 177 8 5668 5675
20. Betts M. R., Brenchley J. M., Price D. A., Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation Journal of Immunological Methods 2003 281 1-2 65 78
21. Lowin B., Mattman C., Hahne M., Tschopp J., Comparison of Fas(Apo-1/CD95)- and perforin-mediated cytotoxicity in primary T lymphocytes International Immunology 1996 8 1 57 63
22. Schmaltz C., Alpdogan O., Horndasch K. J., Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect Blood 2001 97 9 2886 2895