Repeated siRNA application is a precondition for successful mRNA γENaC knockdown in the murine airways

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 75, Issue 3, 2010, Pages 305-310

  Yueksekdag, Guelnihal ^a   Drechsel, Marei ^a   Rößner, Michaela ^a   Schmidt, Christa ^a   Kormann, Michael ^a   Illenyi, Marta C ^a   Rudolph, Carsten ^a,b   Rosenecker, Joseph ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Airways; Cystic fibrosis; ENaC; Gene silencing; In vivo; SiRNA

Indexed keywords

AMILORIDE; CHLORIDE ION; EPITHELIAL SODIUM CHANNEL; EPITHELIAL SODIUM CHANNEL GAMMA SUBUNIT; MESSENGER RNA; SMALL INTERFERING RNA; SODIUM ION; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYSTIC FIBROSIS; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REPEATED DRUG DOSE; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; DNA PRIMERS; EPITHELIAL SODIUM CHANNEL; GENE KNOCKDOWN TECHNIQUES; MICE; POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRACHEA;

EID: 77954540389     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.04.005     Document Type: Article

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