Association between genetic variants in the 8q24 cancer risk regions and circulating levels of androgens and sex hormone-binding globulin

Cancer Epidemiology Biomarkers and Prevention

Volumn 19, Issue 7, 2010, Pages 1848-1854

  Chu, Lisa W ^a   Meyer, Tamra E ^a   Li, Qizhai ^b   Menashe, Idan ^a   Yu, Kai ^a   Rosenberg, Philip S ^a   Huang, Wen Yi ^a   Quraishi, Sabah M ^a   Kaaks, Rudolf ^c   Weiss, Jocelyn M ^a   Hayes, Richard B ^a   Chanock, Stephen J ^a   Hsing, Ann W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b CHINESE ACADEMY OF SCIENCES   (China)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTENEDIONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CANCER RISK; CAUCASIAN; CENTROMERE; CHROMOSOME 8Q; CHROMOSOME 8Q24; CONTROLLED STUDY; GENETIC VARIABILITY; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; BLOOD; CHROMOSOME 8; COLORECTAL TUMOR; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; LUNG TUMOR; METABOLISM; MIDDLE AGED; NEOPLASM; OVARY TUMOR; PATHOLOGY; PROSTATE TUMOR; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR;

AGED; ANDROGENS; CHROMOSOMES, HUMAN, PAIR 8; COLORECTAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASMS; OVARIAN NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; RISK FACTORS; SEX HORMONE-BINDING GLOBULIN;

EID: 77954526096     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-10-0101     Document Type: Article

References (29)

1. Amundadottir LT, Sulem P, Gudmundsson J, et al. A common variant associated with prostate cancer in European and African populations. Nat Genet 2006;38:652-8.
2. Gudmundsson J, Sulem P, Manolescu A, et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet 2007;39:631-7.
3. Haiman CA, Patterson N, Freedman ML, et al. Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet 2007;39:638-44.
4. Yeager M, Orr N, Hayes RB, et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 2007;39:645-9. (Pubitemid 46676108)
5. Thomas G, Jacobs KB, Yeager M, et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet 2008;40:310-5.
6. Eeles RA, Kote-Jarai Z, Giles GG, et al. Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet 2008;40:316-21.
7. Yeager M, Chatterjee N, Ciampa J, et al. Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet 2009;41:1055-7.
8. Easton DF, Pooley KA, Dunning AM, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007;447:1087-93.
9. Haiman CA, Le Marchand L, Yamamato J, et al. A common genetic risk factor for colorectal and prostate cancer. Nat Genet 2007;39:954-6.
10. Tomlinson I, Webb E, Carvajal-Carmona L, et al. A genomewide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet 2007;39:984-8. (Pubitemid 47185182)
11. Zanke BW, Greenwood CM, Rangrej J, et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 2007;39:989-94.
12. Kiemeney LA, Thorlacius S, Sulem P, et al. Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet 2008;40:1307-12.
13. Panagopoulos I, Moller E, Collin A, Mertens F. The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1. Oncol Rep 2008;20:1029-33.
14. Sole X, Hernandez P, de Heredia M, et al. Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility. BMC Genomics 2008;9:12. (Pubitemid 351256329)
15. Pomerantz MM, Beckwith CA, Regan MM, et al. Evaluation of the 8q24 prostate cancer risk locus and MYC expression. Cancer Res 2009;69:5568-74.
16. Tuupanen S, Turunen M, Lehtonen R, et al. The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nat Genet 2009;41:885-90.
17. Prorok PC, Andriole GL, Bresalier RS, et al. Design of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Control Clin Trials 2000;21:273-309S.
18. Hayes RB, Reding D, Kopp W, et al. Etiologic and early marker studies in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Control Clin Trials 2000;21:349-55S.
19. Weiss JM, Huang WY, Rinaldi S, et al. Endogenous sex hormones and the risk of prostate cancer: a prospective study. Int J Cancer 2008;122:2345-50.
20. Morris PD, Malkin CJ, Channer KS, Jones TH. A mathematical comparison of techniques to predict biologically available testosterone in a cohort of 1072 men. Eur J Endocrinol 2004;151:241-9.
21. Efron B, Tibshirani RJ. An introduction to the bootstrap. Chapman & Hall/CRC; 1993.
22. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21:263-5. (Pubitemid 40202029)
23. Lejeune-Lenain C, Van Cauter E, Desir D, Beyloos M, Franckson JR. Control of circadian and episodic variations of adrenal androgens secretion in man. J Endocrinol Invest 1987;10:267-76. (Pubitemid 17097631)
24. Plymate SR, Tenover JS, Bremner WJ. Circadian variation in testosterone, sex hormone-binding globulin, and calculated non-sex hormone-binding globulin bound testosterone in healthy young and elderly men. J Androl 1989;10:366-71.
25. Zheng SL, Sun J, Cheng Y, et al. Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans. J Natl Cancer Inst 2007;99:1525-33.
26. Salinas CA, Kwon E, Carlson CS, et al. Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2008;17:1203-13.
27. Al Olama AA, Kote-Jarai Z, Giles GG, et al. Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat Genet 2009;41:1058-60.
28. Jia L, Landan G, Pomerantz M, et al. Functional enhancers at the gene-poor 8q24 cancer-linked locus. PLoS Genet 2009;5:e1000597.
29. Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O'Donnell CJ, de Bakker PIW. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 2008;24:2938-9.